Results 41 to 50 of about 24,867 (235)

Circulating αKlotho influences phosphate handling by controlling FGF23 production [PDF]

, 2012
The FGF23 coreceptor αKlotho (αKL) is expressed as a membrane-bound protein (mKL) that forms heteromeric complexes with FGF receptors (FGFRs) to initiate intracellular signaling.
Allen, Matthew R., Breyer, Matthew D, Broderick, Carol, Burr, David B., Cass, Taryn A, Clinkenbeard, Erica L., Farrow, Emily G, Guo, Qianxu, Kharitonenkov, Alexei, Ma, Y Linda, O'Bryan, Linda M, Roberts, Jessica L, Saha, Joy, Smith, Rosamund C, Summers, Lelia J, Sun, Haijun, White, Kenneth E, Wilson, Jonathan M, Zeng, Qing Qiang   +18 more
core   +1 more source

Vascular Calcification: Mechanisms, Models, and Therapies

iNew Medicine, EarlyView.
ABSTRACT Vascular calcification represents an active multifactorial process that mirrors several key features of skeletal bone mineralization. Clinically, it is characterized by diminished arterial compliance and increased arterial wall stiffness, both of which serve as independent predictors of significant adverse cardiovascular events.
Wenya Zhu, Shu Yang, Ziyi Chen, Xiaoxiao Yang, Zhen Liang, Yuanli Chen   +5 more
wiley   +1 more source

FGF23-related hypophosphatemia in a patient with small cell lung cancer: a case report and literature review

Endocrine Journal, 2023
Although there are a few case reports of patients with small cell lung cancer developing hypophosphatemia, detailed information on this condition is scarce.
Hajime Kato, Soichiro Kimura, Maho Taguchi, Takashi Sunouchi, Yoshitomo Hoshino, Naoko Hidaka, Nadia Edvige Foligno, Minae Koga, Katsunori Manaka, Hiroyuki Tamiya, Masanori Kawakami, Hidenori Kage, Yoichi Yasunaga, Masaomi Nangaku, Noriko Makita, Nobuaki Ito   +15 more
doaj   +1 more source

Long-term Observation of Osteomalacia Caused by Adefovir-Induced Fanconi’s Syndrome [PDF]

, 2014
A 64-year-old man suffering polyarthralgia and bone pain was referred to our hospital. Renal dysfunction, hypophosphatemia and increased levels of bone alkaline phosphatase were found.
Ebara, Hirotaka, Hanayama, Yoshihisa, Hidan, Ko, Kawabata, Tomoko, Otsuka, Fumio, Sugiyama, Hitoshi, Takaki, Akinobu, Terasaka, Tomohiro, Ueta, Eijiro, Waseda, Koichi   +9 more
core   +1 more source

Mineral‐targeted alkaline phosphatase improves bone graft‐mediated alveolar bone defect healing in mice

Journal of Periodontology, EarlyView.
Abstract Background Alveolar bone loss challenges tooth retention and implant placement. Freeze‐dried bone allograft (FDBA) is widely used for alveolar ridge preservation but has limitations in resorption rate and healing time. In this proof‐of‐concept study, we tested whether pro‐mineralization enzyme, tissue‐nonspecific alkaline phosphatase (TNAP ...
Kedith Sawangsri, Aonjittra Phanrungsuwan, Binnaz Leblebicioglu, José Luis Millán, Brian L. Foster   +4 more
wiley   +1 more source

Yield of diagnostic tests in unexplained renal hypophosphatemia: a case series

BMC Nephrology, 2018
Background Isolated renal hypophosphatemia may be inherited or acquired. An increasing number of patients with unexplained renal hypophosphatemia is being referred to our clinics, but the optimal diagnostic work-up is not known.
A. P. Bech, E. J. Hoorn, R. Zietse, J. F. M. Wetzels, T. Nijenhuis   +4 more
doaj   +1 more source

Outpatient preoperative parenteral nutrition in malnourished surgical patients: A feasibility study (the OPPORTUNITY study)

Nutrition in Clinical Practice, EarlyView.
Abstract Preoperative parenteral nutrition (PN) improves outcomes in malnourished surgical patients. Traditionally, this requires hospital admission, increasing length of stay and costs—challenges worsened by limited hospital bed availability. Outpatient PN may offer a feasible alternative.
Narisorn Lakananurak, Leah Gramlich
wiley   +1 more source

Increased Metabolic Rate in X-linked Hypophosphatemic Mice [PDF]

, 1986
Hyp mice are a model for human X-linked hypophosphatemia, the most common form of vitamin D-resistant rickets. It has previously been observed that Hyp mice have a greater food consumption per gram body weight than do normal mice.
Meyer, M. H., Meyer, Ralph A., Vaughn, Linda K.   +2 more
core   +1 more source

Feeding Management of African Rhinos (Ceratotherium simum, Diceros bicornis) in European Zoos

Zoo Biology, EarlyView.
The average estimated diets (in % dry matter) of white rhinos (C. simum) and black rhinos (D. bicornis) in European zoos differ in the proportion of (pelleted) compound feed and other non‐forage items. The reason for this difference is elusive but possibly related to creating more complicated diets for browsers. ABSTRACT White rhinos (WR, Ceratotherium
Gila Sauspeter, Marcus Clauss, Sylvia Ortmann, Andrew J. Abraham, Rebecca Biddle, Lars Versteege, Marcin Przybyło   +6 more
wiley   +1 more source

Sorafenib dose escalation is not uniformly associated with blood pressure elevations in normotensive patients with advanced malignancies. [PDF]

, 2014
Hypertension after treatment with vascular endothelial growth factor (VEGF) receptor inhibitors is associated with superior treatment outcomes for advanced cancer patients.
Bakris, GL, Cohen, EEW, Fleming, GF, House, LK, Karovic, S, Karrison, TG, Levine, MR, Maitland, ML, Ratain, MJ, Rudek, MA, Thomeas, V, Wen, Y, Wright, JJ, Wu, K   +13 more
core   +2 more sources