Results 71 to 80 of about 13,942 (231)

Development of skin hypopigmentation in a patient with metastatic papillary carcinoma thyroid treated with Sorafenib.

open access: yes, 2013
Background: Sorafenib can be considered as the effective option of treatment in patients with metastatic radioiodine refractory differentiated thyroid cancers. The cutaneous manifestations of Sorafenib include rash, desquamation, hand foot skin reactions,
Hussain, Syed Zubair   +7 more
core   +1 more source

Extensive Extragenital Lichen Sclerosus-Like Lesions in a Patient with Junctional Epidermolysis Bullosa

open access: yesIndian Dermatology Online Journal
Epidermolysis bullosa (EB) is a heterogeneous group of genetic disorders characterized by the formation of blisters either spontaneously or at the sites of trauma. These heal with post-inflammatory hypopigmentation, scarring, or milia formation.
Smriti Gupta   +4 more
doaj   +1 more source

Vitiligo Vitiligo

open access: yesAnais Brasileiros de Dermatologia, 2004
O vitiligo é doença de pele de causa desconhecida que acomete cerca de 1% da população, comprometendo de modo semelhante homens e mulheres, preferencialmente entre 10 e 30 anos de idade.
Denise Steiner   +4 more
doaj   +1 more source

Age‐related dermatoscopic features of excised melanomas versus nevi in 832 high risk patients

open access: yesJDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Summary Background and objectives Melanocytic nevi show distinct age‐related dermoscopic patterns. However, data on age‐related patterns of melanomas are lacking. This study aimed to identify age‐related static and dynamic dermoscopic patterns of melanomas. Patients and methods Explorative cross‐sectional cohort study between October 1996 and May 2012,
Jana Burghaus‐Zhang   +6 more
wiley   +1 more source

Human Skin Lightening Efficacy of Resveratrol and Its Analogs: From in Vitro Studies to Cosmetic Applications

open access: yesAntioxidants, 2019
Antioxidants are deemed useful in controlling oxidative stress associated with extrinsic skin aging and pigmentation disorders. Resveratrol is a polyphenol compound found in many edible plants such as Vitis vinifera, and its inhibitory effects on the ...
Yong Chool Boo
doaj   +1 more source

PDE4 Inhibition in Dermatologic Disease: Impacts Beyond Inflammation

open access: yesInternational Journal of Dermatology, EarlyView.
This graphical abstract demonstrates the comprehensive mechanism of PDE4 inhibition in skin physiology. By increasing intracellular cAMP and activating PKA, PDE4 inhibitors exert pleiotropic effects, including immune modulation, pigmentation regulation, barrier enhancement, sensory neuron modulation, and improved wound healing with reduced fibrosis ...
Keana Khodadad   +2 more
wiley   +1 more source

Home-based narrowband UVB, topical corticosteroid or combination for children and adults with vitiligo: HI-Light Vitiligo three-arm RCT

open access: yesHealth Technology Assessment, 2020
Background: Systematic reviews suggest that narrowband ultraviolet B light combined with treatments such as topical corticosteroids may be more effective than monotherapy for vitiligo.
Jonathan M Batchelor   +34 more
doaj   +1 more source

Epidermal necrolysis sequelae: A cohort study on prevalence and risk factors

open access: yesJournal of the European Academy of Dermatology and Venereology, EarlyView.
Long‐term sequelae after epidermal necrolysis are frequent, multiple and often severe. Cutaneous, ocular and psychological complications are more frequent, with significant socioeconomic impact. Cluster analysis identifies distinct patient profiles, highlighting the need for personalized multidisciplinary follow‐up.
Thanh Vy Nguyen   +9 more
wiley   +1 more source

Regional Nerve Blocks and OnabotulinumtoxinA in the Management of Trigeminal Trophic Syndrome: A Case Report of a Novel Multimodal Approach

open access: yesOral Surgery, EarlyView.
ABSTRACT Objective Trigeminal trophic syndrome (TTS) is a rare condition caused by trigeminal nerve injury, classically characterized by anaesthesia, paresthesia and facial ulceration. We present two cases of TTS successfully managed with regional nerve blocks and onabotulinumtoxinA. Methods Two patients—a 54‐year‐old woman and a 65‐year‐old man—with a
Shamin Masrour, Rhea Sudhakaran
wiley   +1 more source

Setmelanotide in Bardet‐Biedl Syndrome: A Case Report

open access: yesPediatric Dermatology, EarlyView.
ABSTRACT Setmelanotide is a melanocortin‐4‐receptor agonist used for the treatment of hyperphagia in the genetic obesity syndrome Bardet‐Biedl. Presented is a case of diffuse hyperpigmentation in a patient treated with setmelanotide, which represents the most common side effect of this medication.
Shelby Smith   +2 more
wiley   +1 more source

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