Lupus anticoagulant hypoprothrombinemia syndrome: A case report [PDF]
Abstract Lupus anticoagulant hypoprothrombinemia syndrome (LAHPS) is a rare entity associated with an increased risk of hemorrhage. Corticosteroids have been used in its treatment with favorable results. We present the case of a 54‐year‐old female patient with a personal history of Lupus diagnosed with LAHPS following an episode of cerebellar ...
Natalia Acedo +5 more
openalex +2 more sources
Therapeutic Plasma Exchange After Spontaneous Intracranial Hemorrhage for a Patient With Antiphospholipid Syndrome and Lupus Anticoagulant Hypoprothrombinemia. [PDF]
ABSTRACT Antiphospholipid syndrome (APS) is characterized by the presence of antiphospholipid antibodies (aPL), macro‐ and micro‐vascular thromboembolic complications. Lupus anticoagulant‐hypoprothrombinemia (LAHPS) may confound the diagnosis and management of bleeding. Catastrophic APS has a category 1 indication for therapeutic plasma exchange (TPE).
Nicholas J +4 more
europepmc +2 more sources
Lupus anticoagulant hypoprothrombinemia syndrome in Bence-Jones protein κ-type multiple myeloma patient with phosphatidylserine-dependent antiprothrombin antibody. [PDF]
Hara Y +7 more
europepmc +3 more sources
Key Clinical Message Lupus anticoagulant caused aPTT prolongation in rare case can cause bleeding tendency especially when combined with other hemostasis abnormalities. In such cases, aPTT value can be corrected by immunosuppressants within several days of treatment.
Marlena Frydrysiak +3 more
wiley +1 more source
Systemic lupus erythematosus (SLE) is a chronic autoimmune disease with unpredictable course and flares. The clinical manifestation can vary from mild to severe and life‐threatening disease. Infection is the primary cause of mortality in hospitalized SLE patients.
Mohamed M. Cheikh +7 more
wiley +1 more source
A case of congenital prothrombin deficiency with two concurrent mutations in the prothrombin gene
Abstract Congenital prothrombin deficiency is an extremely rare, autosomal recessive bleeding disorder with a prevalence of 1 in 2 million individuals. Here, we report a case of congenital prothrombin deficiency with two concurrent mutations in the prothrombin gene (F2), affecting the heavy B chain.
Eman M. Mansory +5 more
wiley +1 more source
Monitoring of anticoagulation in thrombotic antiphospholipid syndrome
Abstract Anticoagulation is central to the management of thrombotic antiphospholipid syndrome (APS). The standard anticoagulant treatment for thrombotic APS is life‐long warfarin or an alternative vitamin K antagonist. The role of direct oral anticoagulants for thrombotic APS is not established due to the lack of definitive evidence and has recently ...
Hannah Cohen +2 more
wiley +1 more source
Pathophysiology of coronavirus disease 2019 for wound care professionals
Abstract There is pressing urgency to understand the pathogenesis of the severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) which causes Coronavirus disease 2019 (COVID‐19). The tissue tropism of SARS‐CoV‐2 includes not only the lung but also the vascular and integumentary systems.
Sammy Al‐Benna
wiley +1 more source
We report a case of acquired factor XI deficiency with lupus anticoagulant (LA) in a 28‐year‐old primigravida who presented with finger pain and eruptions on her palms and fingers during the 3rd trimester of pregnancy. The patient complained of pain and reddening of the fingers at 30 weeks of gestation.
Rie Nakajima +6 more
wiley +1 more source
Síndrome de anticoagulante lúpico-hipoprotrombinemia (SAL-HPT): la paradoja fisiopatológica entre el sangrado y la trombosis en el perfil triple positivo de anticuerpos antifosfolípidos y el lupus eritematoso sistémico [PDF]
The lupus anticoagulant–hypoprothrombinemia syndrome (LAHPS) is a rare entity associated with autoimmune diseases. It may present hemorrhage without a concomitant reduction in thrombotic risk.
Domínguez-Quintero, Giovanni Francisco +1 more
core +2 more sources

