Results 51 to 60 of about 13,203 (228)

Microbial‐Metabolite Signatures Are Associated With Glucocorticoid Responsiveness in Chronic Rhinosinusitis With Nasal Polyps

International Forum of Allergy &Rhinology, EarlyView.
ABSTRACT Background Patients with chronic rhinosinusitis with nasal polyps (CRSwNP) exhibit heterogeneous responses to oral glucocorticoids (GCs), but the biological basis of this variability remains unclear. Objective To identify gut microbiome‒plasma metabolomic signatures associated with GC responsiveness in CRSwNP patients and to compare their ...
Ying‐Ying Zhang, Xin‐Yu Ding, Mei‐Ping Lu, Yan‐Bing Chen, Ye Yuan, Lin Jiang, Min Zhang, Lei Cheng   +7 more
wiley   +1 more source

Management of Post-Infectious Anosmia and Hyposmia: A Systematic Review.

, 2022
BACKGROUND: Anosmia and hyposmia significantly affect patients\u27 quality of life and have many etiologies, including trauma, inflammatory conditions including chronic rhinosinusitis, neoplasm, and viral infections, such as rhinovirus and SARS-CoV-2 ...
Knisely, Anna, Illing, Elisa A, Saltagi, Mohamad Z, Saltagi, Abdul K, Higgins, Thomas S, Nag, Amit K, Ting, Jonathan Y, Wu, Arthur W   +7 more
core   +1 more source

Association between hyposmia and cognitive decline in patients with Parkinson's disease

, 2021
Cilj: Utvrditi zastupljenost i povezanost hiposmije s prisutnošću kognitivnih promjena u osoba oboljelih od Parkinsonove bolesti, istražiti zastupljenost i povezanost hiposmije s kognitivnim promjenama u zdravih ispitanika te utvrditi koliki je udio ...
Puhanić, Josip
core   +1 more source

Biologics Adoption in CRSwNP and the Associated Decline in Endoscopic Sinus Surgery: A Longitudinal Claims Database Study

International Forum of Allergy &Rhinology, EarlyView.
ABSTRACT Background Biologic treatments were introduced for chronic rhinosinusitis with nasal polyps (CRSwNP) in 2019. Treatment algorithms for medically refractory CRSwNP remain open, with patients choosing among surgery, biologics, or both. Real‐world utilization of surgery and biologics remains incompletely characterized.
Stephanie Shintani Smith, Sam L. Kaefer, Harsh Duvvuru, Robert C. Kern, Brent A. Senior, Vijay R. Ramakrishnan   +5 more
wiley   +1 more source

Psychophysical Evaluation of the Olfactory Function: European Multicenter Study on 774 COVID-19 Patients

Pathogens, 2021
Background: The objective evaluation of the olfactory function of coronavirus disease 2019 patients is difficult because of logistical and operator-safety problems.
Luigi Angelo Vaira, Jerome R. Lechien, Mohamad Khalife, Marzia Petrocelli, Stephane Hans, Lea Distinguin, Giovanni Salzano, Marco Cucurullo, Piero Doneddu, Francesco Antonio Salzano, Federico Biglioli, Fabrice Journe, Andrea Fausto Piana, Giacomo De Riu, Sven Saussez   +14 more
doaj   +1 more source

Unawareness of Hyposmia in Elderly People With and Without Parkinson\u27s Disease

, 2016
Background: Hyposmia is common in Parkinson\u27s disease (PD) and is also observed with normal aging. It can be ascertained through objective testing, but it is unclear whether patients are aware of deficits and whether this has implications for ...
Shill, Holly A., Caviness, John N., Driver-Dunckley, Erika, Belden, Christine, Beach, Thomas G., Jacobson, Sandra, Sabbagh, Marwan N., Hentz, Joseph G., Adler, Charles H.   +8 more
core   +1 more source

Clinical and Dopamine Depletion Patterns in Hyposmia- and Dysautonomia-Dominant Parkinson's Disease

, 2021
Background: Olfactory or autonomic dysfunction is one of the earliest prodromal symptoms of Parkinson's disease (PD). It has not been investigated whether PD patients have different phenotypes depending on the presence of these prodromal symptoms ...
윤미진, 이필휴, 손영호, 유한수, 예병석   +4 more
core   +1 more source

Cognitive Dysfunction in Chronic Rhinosinusitis: A Scoping Review

International Forum of Allergy &Rhinology, EarlyView.
ABSTRACT Background Cognitive dysfunction is increasingly recognized as an extra‐nasal manifestation of chronic rhinosinusitis (CRS). This scoping review characterizes the primary evidence on cognition in adult CRS, covering measures, treatment response, and incident dementia.
Luke M. O'Neil, Hannan A Qureshi, Logan Lindemann, David J. Cvancara, Ashton E. Lehmann, Aria Jafari   +5 more
wiley   +1 more source

Efficacy and Predictors of Response to Biologic Therapy and Endoscopic Sinus Surgery in Patients With Nasal Polyps: A Systematic Review

International Forum of Allergy &Rhinology, EarlyView.
ABSTRACT Background Biologics and endoscopic sinus surgery (ESS) treat refractory chronic rhinosinusitis with nasal polyposis (CRSwNP), but direct comparisons are lacking. We synthesized efficacy and subgroup data across randomized controlled trials (RCTs) of biologics and ESS.
Arun Chakravorty, Matthew E. Lin, Rory Lubner, Jess C. Mace, Jeffrey Suh, Jivianne Lee, Marilene Wang, Sarah Wise, Naweed Chowdhury, Zachary M. Soler, Justin Turner, Timothy L. Smith, Myung Sim, Daniel M. Beswick   +13 more
wiley   +1 more source

Behavioral Phenotype in the TgF344-AD Rat Model of Alzheimer’s Disease

Frontiers in Neuroscience, 2020
Alzheimer’s disease (AD) is a progressive neurodegenerative disease resulting in cognitive decline. A unique rat model, TgF344-AD, recapitulates pathological hallmarks of AD. We used a longitudinal design to address the timing of expression of behavioral
Rachel Michelle Saré, Spencer K. Cooke, Leland Krych, Patricia M. Zerfas, Robert M. Cohen, Carolyn Beebe Smith   +5 more
doaj   +1 more source