Results 81 to 90 of about 13,203 (228)

Olfactory dysfunction as a diagnostic and prognostic marker for movement disorders

Annals of Movement Disorders
Olfactory dysfunction (OD) is a common nonmotor symptom observed in several movement disorders. The severity and pattern of olfactory impairment vary among these conditions.
Aliasghar Peyvandi, Shahrokh Khoshsirat, Narges Bazgir, Amirreza Zaker, Azin Tahvildari, Somayeh Niknazar, Sara Mohammadi, Mehri Salari   +7 more
doaj   +1 more source

Comparison of cognitive scores between normosmia and hyposmia.

, 2015
1p-value includes Simes’ correction procedure for multiple comparisons. SD: standard deviation. Bold: significant comparison (.05 level).*Moderate to high effect size (|d|≥0.50).Comparison of cognitive scores between normosmia and hyposmia.
Rosa Baños (310770), Francisco J. Tinahones (141606), Cristina Giner-Bartolomé (591673), Rafael de la Torre (125317), Antoni Pastor (423963), Gema Frühbeck (161466), Ana B. Fagundo (310764), Roser Granero (310767), Javier Gómez-Ambrosi (260192), Fernando Fernández-Aranda (310776), Felipe F. Casanueva (130305), Ana B. Crujeiras (489783), Mohammed Anisul Islam (756205), Cristina Botella (310769), José M. Menchón (211928), Jose M. Fernández-Real (2139958), Susana Jiménez-Murcia (310765)   +16 more
core   +1 more source

JAK2 Variant and Parkinsonian Syndromes: Coincidence or Pathophysiological Link?

Movement Disorders Clinical Practice, EarlyView.
Abstract Background JAK2 variants are a hallmark of myeloproliferative neoplasms (MPNs), including polycythemia vera and essential thrombocythemia. These disorders are often associated with thrombotic and inflammatory complications. From a movement disorder perspective, chorea is a rare but well‐recognized neurological occurrence in this context ...
Elena Ardila Jurado, Koustubh Bavdhankar, Divyani Garg, Francesca Magrinelli, Huw R. Morris, Kailash P. Bhatia   +5 more
wiley   +1 more source

The Global Parkinson's Disease Genetics (GP2) Genome Browser

Movement Disorders, EarlyView.
Abstract Background Large‐scale sequencing initiatives have generated extensive genomic resources essential for variant interpretation, yet their effective use often requires bioinformatics expertise. To support identification of Parkinson's disease (PD) risk and disease‐causing variants, we developed an open‐access, summary‐level genomic data browser.
Zih‐Hua Fang, Riley H. Grant, Dan Vitale, Carlos F. Hernandez, Samantha Hong, Hampton L. Leonard, Mary B. Makarious, Lara M. Lange, Matthew Solomonson, Peter Heutink, Allison A. Dilliott, Kamalini Ghosh Galvelis, Mike A. Nalls, Andrew B. Singleton, Cornelis Blauwendraat, the Global Parkinson's Genetics Program (GP2)   +15 more
wiley   +1 more source

Neural Basis of Hyposmia in Alzheimer’s Disease

, 2011
At the beginning of twenty century Alois Alzheimer described the pathology that now bears his name (Alzheimer, 1907). Over a hundred years later, Alzheimer’s disease (AD) is the most common cause of dementia in developed countries. Here eighteen million people are currently affected and the number of patients is expected to increase dramatically with ...
Saiz Sánchez, Daniel, Rosa Prieto, Carlos de la, Úbeda Bañón, Isabel María, Martínez Marcos, Alino José   +3 more
openaire   +3 more sources

Greater Motor and Nonmotor Burden at Diagnosis Is Associated With Amyloid Copathology in Parkinson's Disease

Movement Disorders, EarlyView.
Abstract Background Concurrent Alzheimer's disease pathology is increasingly recognized as a poor prognostic factor in Parkinson's disease (PD), yet reliable clinical indicators for early identification of AD copathology remain poorly established.
Han Kyu Na, Yeeun Sun, Chan Wook Park, Jung Hyun Lee, Yun Young Choi, Quynh Phuong Vo, Seok Jong Chung, Han Soo Yoo, Chul Hyoung Lyoo, Young H. Sohn, Jin Yong Hong, Phil Hyu Lee   +11 more
wiley   +1 more source

The Hidden Epidemic of Smell Loss (Hyposmia) in the United States

, 2015
There is a hidden epidemic of hyposmia in the United States. While most otolaryngologists may see one or two patients with hyposmia yearly there are as many as 21 million people in the United States with hyposmia.
Robert Henkin
core  

Apathy in Lewy Body Disorders: A Position Paper

Movement Disorders, EarlyView.
Abstract Apathy is one of the most prevalent and disabling non‐motor symptoms in Parkinson's disease (PD) and dementia with Lewy bodies (DLB), collectively referred to as Lewy body disorders (LBDs). It is associated with reduced quality of life, accelerated cognitive decline, increased caregiver burden, and poorer functional outcomes, yet remains ...
Jaime Kulisevsky, Lidia Bojtos, Milica G. Kramberger, Elisa Mantovani, Iulia Murasan, Jose‐Alberto Palma, Karolina Poplawska‐Domaszewicz, Anna Sauerbier, Kallol Ray Chaudhuri, Per Odin, Daniel Weintraub, Anette Schrag, Cristian Falup‐Pecorariu   +12 more
wiley   +1 more source

Comparative analysis of GSTM1/GSTT1 null alleles and Ile105Val GSTP1 variant in patients with Nasal Polyposis and hyposmia in a Romanian population group

Romanian Journal of Laboratory Medicine, 2013
Introducere. Polimorfisme genelor care codifică glutation S-transferazele (GSTM1/GSTT1/GSTP1) ar putea fi unul dintre factorii care pot influenţa variabilitatea susceptibilităţii pentru polipoză nazală şi hiposmie la indivizii sănătoşi sau pacienţii cu ...
Cătană Iuliu Vlad, Popp Radu Anghel, Pop Ioan Victor, Cătană Andreea, Rădeanu Doinel, Maniu Alma, Cosgarea Marcel   +6 more
doaj   +1 more source

Dopamine‐Deficiency‐Related Reorganization of the Somatomotor Network in Prodromal and Early Parkinson's Disease

Movement Disorders, EarlyView.
Abstract Introduction Network attack tolerance (NAT) measures the brain's ability to sustain information flow despite the loss of critical brain regions. In Parkinson's disease (PD), NAT has been linked to cognitive and motor function. However, it remains unclear how dopaminergic degeneration shapes NAT, and whether it relates to motor symptom ...
Adrian L. Asendorf, Verena Dzialas, Thilo van Eimeren, Merle C. Hoenig   +3 more
wiley   +1 more source