Results 21 to 30 of about 47,634 (314)
The spectrum of phenotypes associated with mutations in steroidogenic factor 1 (SF-1, NR5A1, Ad4BP) includes severe penoscrotal hypospadias in 46,XY males without adrenal insufficiency [PDF]
, 2009 OBJECTIVE. Hypospadias is a frequent congenital anomaly but in most cases an underlying cause is not found. Steroidogenic factor 1 (SF-1, NR5A1, Ad4BP) is a key regulator of human sex development and an increasing number of SF-1 (NR5A1) mutations are ...
Achermann, J.C. +9 more
core +2 more sources
Springer Surgery Atlas Series, 2019 Hypospadias is a congenital (present at birth) anomaly of the penis, with the opening of the urethra located anywhere on the underside of the penis instead of the tip (Pic. 1).
M. Renaux-petel +3 more
semanticscholar +1 more source
Renal Subcapsular xenografing of human fetal external genital tissue - A new model for investigating urethral development. [PDF]
, 2017 In this paper, we introduce our novel renal subcapsular xenograft model for the study of human penile urethral and clitoral development. We grafted fifteen intact fetal penes and clitorides 8-11 weeks fetal age under the renal capsules of gonadectomized ...
Baskin, Laurence +6 more
core +2 more sources
Frontiers in Pediatrics, 2020 Purpose: The aim of this study was to systematically review the literature on the complications and postoperative outcomes of children with non-proximal hypospadias.
Yuhao Wu +8 more
semanticscholar +1 more source
Synergistic disruption of external male sex organ development by a mixture of four antiandrogens [PDF]
, 2009 Reproduced with permission from Environmental Health Perspectives.Background: By disrupting the action of androgens during gestation, certain chemicals present in food, consumer products, and the environment can induce irreversible demasculinization and ...
Andreas Kortenkamp +14 more
core +3 more sources
Parental risk factors associated with hypospadias
Archives of Medicine and Health Sciences, 2013 Introduction: Hypospadias is one of the most common congenital anomalies of male external genitalia. It occurs in approximately 1 in 250 newborn. Hypospadias can be defined as an abnormal urethral orifice under surface of the penis with or without ...
Bindhu Suma Shekar, Ramakrishna Avadhani
doaj +1 more source
Severity-Dependent Profile of the Metabolome in Hypospadias
Frontiers in Pediatrics, 2020 Background & Objective: Hypospadias, characterized by the displacement of the opening of the urethra at any point in the medial-ventral side of the penis, is classified upon severity as mild (Type I) and severe (Type II and Type III) hypospadias ...
Coriness Piñeyro-Ruiz +3 more
doaj +1 more source
Fire in the Operating Room During Hypospadias Repair [PDF]
, 2017 Fire in the operating room (OR) is a very distressful and shocking occurrence with potential dramatic consequences. Despite safety rules and rigorous recommendations, such unintentional events do occur every so often.
Boscarelli, Alessandro +5 more
core +2 more sources
Can Testosterone Alter the Degree of Hypospadias? A Comprehensive Study
Journal of Indian Association of Pediatric Surgeons, 2021 Context: In this study, we observed using serial injections of parenteral testosterone whether we can alter the degree of hypospadias. Aims: The aim was to study the effect of testosterone on different parts of the phallus in hypospadias and to see if we
Dasmit Singh Khokar, Ravi Vadilal Patel
doaj +1 more source
L-configuration re-attachment of distal biceps tendon rupture [PDF]
, 2009 In distal biceps tendon ruptures, re-attachment to the radial tuberosity should ensure adequate tendon to bone contact for optimal ...
Charalambous, CP +4 more
core +2 more sources