Results 41 to 50 of about 27,108 (253)

‘Transient immediate orthostatic hypotension’ is preferable to ‘initial’ orthostatic hypotension

Autonomic Neuroscience
A drop of systemic blood pressure (BP) occurring shortly after individuals move from supine or seated position to upright posture with subsequent prompt spontaneous resolution is a common physiological occurrence in humans. If the induced hypotension is severe, lightheadedness or postural instability leading to falls and injury may occur. By consensus,
Benditt DG, Fedorowski A, Sutton R, van Dijk JG, Baron-Esquivas G, Biaggioni I, Brignole M, De Jong JSY, De Lange FJ, Freeman R, Furlan R, Grubb B, Hamdan MH, Kenny RA, Lim PB, Angel MM, Olshansky B, Rafanelli M, Raj SR, Reyes J, Rivasi G, Russo V, Sheldon R, Stewart JM, Thijs R, Ungar A, Van Rossum IA.   +26 more
openaire   +5 more sources

Safety and pharmacokinetics of mosliciguat, a new, inhaled soluble guanylate cyclase activator, in healthy adult subjects

British Journal of Clinical Pharmacology, EarlyView.
Abstract Aim Mosliciguat (BAY 1237592), the first soluble guanylate cyclase (sGC) activator in a dry powder inhaler (DPI), could potentially treat pulmonary hypertension with a more targeted delivery than systemic sGC stimulators. We report safety and tolerability of mosliciguat in healthy men.
Johannes Nagelschmitz, Soundos Saleh, Sandra Ligges, Melanie Seidel‐Greven, Eva Becker‐Pelster, Sylvia M. Nikkho, Stefanie Boxnick, Wolfgang Timmer   +7 more
wiley   +1 more source

The Proportion of Orthostatic Hypotension and Its Relationship with HbA1c Levels in Elderly Patients with Diabetes

Acta Medica Indonesiana, 2016
Aim: to obtain information on the proportion of orthostatic hypotension in elderly patients with diabetes and its relationship with HbA1c levels. Methods: this is a cross-sectional study on 350 patients with diabetes mellitus (DM) aged ≥60 years old who ...
Catarina Budyono, Siti Setiati, Dyah Purnamasari, Cleopas M Rumende   +3 more
doaj   +2 more sources

Severe orthostatic hypotension due to unilateral carotid artery dissection

Neurology International, 2014
A 46-year-old woman was admitted to our hospital with mild right-sided hemiparesis and orthostatic hypotension. Magnetic resonance angiography of the neck showed stenosis of the left distal carotid sinus surrounded by intraluminal hyperintensities on ...
Nobuyuki Ishii, Hitoshi Mochizuki, Akitoshi Taniguchi, Kazutaka Shiomi, Masamitsu Nakazato   +4 more
doaj   +1 more source

The Global, Regional, and National Burden of Young‐Onset Dementia: An Updated Analysis of the Global Burden of Disease Study 2021

Brain Health, EarlyView.
ABSTRACT Young‐onset dementia (YOD), defined as dementia with onset between 40 and 65 years of age, is an emerging global health concern associated with substantial healthcare and socioeconomic burdens. Using data from the Global Burden of Disease Study 2021, this population‐based study analyzed trends in the prevalence, death rates, and disability ...
Yang Zhao, Tai‐Yi Sun, Rui Zhang, Yu‐Hui Liu, Yan‐Jiang Wang   +4 more
wiley   +1 more source

EVALUATION OF ORTHOSTATIC HYPOTENSION BY USING HUTT

Pakistan Armed Forces Medical Journal, 2020
Objective: To determine the prevalence of orthostatic hypotension in our patient population by using Head Up Tilt Test (HUTT). Study Design: Descriptive cross-sectional study.
Qurban Hussain Khan, Muhammad Asad, Waqas Baloch, Mian Muhammad Amer Naseem, Muhammad Shabbir, Azmat Hayat   +5 more
doaj   +1 more source

Antidepressant Misuse in Esports: A Review of Pharmacology, Adverse Effects, Pharmacokinetics and Biomatrix‐Based Detection for Anti‐Doping Applications

Drug Testing and Analysis, EarlyView.
This review highlights the misuse of antidepressants as potential cognitive‐enhancing agents in Esports. Despite pharmacological effects that overlap with those of psychostimulants, antidepressants remain an under‐recognised source of doping in Esports.
Kassim Ali Salum, Shao‐Hsin Hung, Meng‐Tsang Hsieh, Mei‐Chich Hsu, William Chih‐Wei Chang   +4 more
wiley   +1 more source

Treatment strategies for clozapine-induced hypotension: a systematic review

Therapeutic Advances in Psychopharmacology, 2022
Background: Clozapine is the most effective medication for treatment–refractory schizophrenia but is associated with significant adverse drug effects, including hypotension and dizziness, which have a negative impact on quality of life and treatment ...
Timothy David Tanzer, Thomas Brouard, Samuel Dal Pra, Nicola Warren, Michael Barras, Steve Kisely, Emily Brooks, Dan Siskind   +7 more
doaj   +1 more source

Lower Urinary Tract Symptoms as Diagnostic Clues in Parkinsonism: A Practical Framework for Neurologists. [PDF]

Mov Disord Clin Pract
Abstract Background Lower urinary tract symptoms (LUTS) are among the most prevalent nonmotor complaints across the parkinsonian spectrum, yet they remain underutilized as diagnostic and management signals in neurology practice. Although prior reviews have characterized disease‐specific patterns of urinary dysfunction, and recent guidelines address ...
Anis S, Anis O, Lenka A, Siddiqui JH.
europepmc   +2 more sources

A phenomap of TTR amyloidosis to aid diagnostic screening

ESC Heart Failure, Volume 12, Issue 2, Page 1113-1118, April 2025.
Abstract Cardiac amyloidosis due to transthyretin (ATTR) remains an underdiagnosed cause of cardiomyopathy. As awareness of the disease grows and referrals for ATTR increase, clinicians are likely to encounter more atypical forms of the condition in clinical practice.
Alexios S. Antonopoulos, Theodoros Tsampras, George Lazaros, Konstantinos Tsioufis, Charalambos Vlachopoulos   +4 more
wiley   +1 more source