Results 101 to 110 of about 308,666 (390)

Impact of different anesthetic protocols during anesthesia for the establishment of a porcine model of acute kidney injury

open access: yesAnimal Models and Experimental Medicine, EarlyView.
This study details the adaptations required to establish a long‐term anesthetic protocol in pigs. Three protocols were evaluated, with some causing malignant hyperthermia, hypoglycemia, or hemoynamic instability. The final protocol proved effective for developing a porcine AKI model requiring adequate arterial pressure maintenance.
Axel Guilpin   +9 more
wiley   +1 more source

Postural Orthostatic Tachycardia Syndrome Is Associated With Elevated G‐Protein Coupled Receptor Autoantibodies

open access: yesJournal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2019
Background The etiology of postural orthostatic tachycardia syndrome (POTS) is yet to be established. The disorder is often misdiagnosed as chronic anxiety or a panic disorder because the autonomic failure in these patients is not severe.
William T. Gunning   +4 more
doaj   +1 more source

Techniques for preventing hypotension during spinal anaesthesia for caesarean section.

open access: yesCochrane Database of Systematic Reviews, 2017
BACKGROUND Maternal hypotension is the most frequent complication of a spinal anaesthetic for caesarean section with an incidence approaching 100%. Most workers define hypotension as a maternal systolic blood pressure below 70-80% of baseline recordings ...
C. Chooi   +8 more
semanticscholar   +1 more source

Efficacy, Safety, Pharmacokinetics, and Immunogenicity of ABBV‐154 in Adults With Glucocorticoid‐Dependent Polymyalgia Rheumatica: A Phase 2, Randomized, Double‐Blind, Placebo‐Controlled Trial

open access: yesArthritis &Rheumatology, EarlyView.
Objective An unmet need exists for glucocorticoid‐sparing treatments for patients with polymyalgia rheumatica (PMR). The antibody‐drug conjugate ABBV‐154 comprises adalimumab conjugated to a glucocorticoid receptor modulator. We evaluated ABBV‐154 versus placebo in patients with glucocorticoid‐dependent PMR.
Robert F. Spiera   +14 more
wiley   +1 more source

BLITZ‐HF: a nationwide initiative to evaluate and improve adherence to acute and chronic heart failure guidelines

open access: yesEuropean Journal of Heart Failure, Volume 24, Issue 11, Page 2078-2089, November 2022., 2022
Aims To assess adherence to guideline recommendations among a large network of Italian cardiology sites in the management of acute and chronic heart failure (HF) and to evaluate if an ad‐hoc educational intervention can improve their performance on several pharmacological and non‐pharmacological indicators.
Michele Massimo Gulizia   +197 more
wiley   +1 more source

Vasorelaxing Action of the Kynurenine Metabolite, Xanthurenic Acid: The Missing Link in Endotoxin-Induced Hypotension?

open access: yesFrontiers in Pharmacology, 2017
The kynurenine pathway of tryptophan metabolism is activated by pro-inflammatory cytokines. L-kynurenine, an upstream metabolite of the pathway, acts as a putative endothelium-derived relaxing factor, and has been hypothesized to play a causative role in
Carmine Vecchione   +14 more
doaj   +1 more source

Effect of interscalene brachial plexus block on heart rate variability [PDF]

open access: yesKorean Journal of Anesthesiology, 2013
BackgroundInterscalene brachial plexus block (ISB) may be followed by cardiovascular instability. Until date, there is no clear picture available about the underlying mechanisms of ISB.
Marina Simeoforidou   +6 more
doaj   +1 more source

Guideline‐directed medical therapy in patients undergoing transcatheter edge‐to‐edge repair for secondary mitral regurgitation

open access: yesEuropean Journal of Heart Failure, Volume 24, Issue 11, Page 2152-2161, November 2022., 2022
Triple guideline‐directed medical therapy (GDMT) prescription was associated with a lower 2‐year mortality compared to non‐triple GDMT prescription (A). Such association was observed in patients with concomitant comorbidities (B). CI, confidence interval; CKD, chronic kidney disease; CMP, cardiomyopathy; HR, hazard ratio; MRA, mineralocorticoid ...
Satoshi Higuchi   +36 more
wiley   +1 more source

Brain and heart connections: The trigeminocardiac reflex!

open access: yesJournal of Neuroanaesthesiology and Critical Care, 2017
Trigeminocardiac reflex (TCR) is a well-established neurogenic reflex although its exact mechanism and clinical significance remain unclear. This reflex may be incited by stimulation of the trigeminal nerve anywhere along its course starting from the ...
Gyaninder P. Singh, Tumul Chowdhury
doaj   +1 more source

Hypotension in patients administered indigo carmine containing impurities -A case report- [PDF]

open access: yesKorean Journal of Anesthesiology, 2011
Indigo carmine has been used for eight decades with few adverse effects. Several of our patients, however, experienced severe hypotensive episodes after indigo carmine administration within a period of one month.
Sung-Hoon Kim   +4 more
doaj   +1 more source

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