Results 131 to 140 of about 308,666 (390)

Diagnosis and treatment of orthostatic hypotension

Lancet Neurology, 2022
W. Wieling, H. Kaufmann, V. Claydon, V. K. Wijnen, M. Harms, Stephen P. Juraschek, R. Thijs   +6 more
semanticscholar   +1 more source

A companion to the preclinical common data elements and case report forms for in vivo rodent neuroimaging: A report of the TASK3‐WG3 Neuroimaging Working Group of the ILAE/AES Joint Translational Task Force

Epilepsia Open, EarlyView., 2022
Abstract The International League Against Epilepsy/American Epilepsy Society (ILAE/AES) Joint Translational Task Force established the TASK3 working groups to create common data elements (CDEs) for various aspects of preclinical epilepsy research studies, which could help improve the standardization of experimental designs.
Erwin A. van Vliet, Riikka Immonen, Ofer Prager, Alon Friedman, Jens P. Bankstahl, David K. Wright, Terence J. O'Brien, Heidrun Potschka, Olli Gröhn, Neil G. Harris   +9 more
wiley   +1 more source

Recurrent episodes of life-threatening vasodilatory shock following unintentional intoxication with amlodipine

Hellenic Journal of Cardiology, 2017
Calcium channel blockers (CCBs) have a narrow therapeutic index, and their intake in excess is associated with a critical clinical presentation of sustained hypotension and non-cardiogenic pulmonary edema, which are difficult to treat. Unfortunately, the
Chris J. Kapelios, MD, George Karamanakos, MD, Stavros Liatis, MD, Ph.D., Magda Sarafadi, MD, Marios Polizois, MD, Ioannis Papoutsis, MD, Ph.D., Alexander D. Kokkinos, MD, Ph.D.   +6 more
doaj   +1 more source

Relationship between Perioperative Hypotension and Perioperative Cardiovascular Events in Patients with Coronary Artery Disease Undergoing Major Noncardiac Surgery

Anesthesiology, 2019
What We Already Know about This TopicPerioperative hypotension is associated with cardiovascular events in patients having noncardiac surgery, but it is unknown if the severity of preexisting coronary artery disease determines susceptibility to the ...
P. Roshanov, T. Sheth, E. Duceppe, V. Tandon, A. Bessissow, M. Chan, C. Butler, B. Chow, J. Khan, P. Devereaux   +9 more
semanticscholar   +1 more source

A Phase 1C, Open Label, Single Ascending Dose Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of DM199 Administered Intravenously with a Polyvinyl Chloride Bag in Adult Healthy Subjects and Adults Recently Taking Angiotensin‐Converting Enzyme Inhibitors

Clinical Pharmacology in Drug Development, EarlyView.
Abstract This small phase 1C, open‐label, single ascending dose study evaluated the safety, tolerability, and pharmacokinetics (PKs) of DM199, a recombinant form of human tissue kallikrein‐1 (KLK1). A small sample size of both healthy subjects and hypertensive adults recently taking angiotensin‐converting enzyme inhibitors was studied. KLK1 has a known
Michael Giuffre, Annette D. Lista, Nick Paulson, Lorianne Masuoka   +3 more
wiley   +1 more source

Contemporary management of pain in cirrhosis: Toward precision therapy for pain

Hepatology, EarlyView., 2022
Abstract Chronic pain is highly prevalent in patients with cirrhosis and is associated with poor health‐related quality of life and poor functional status. However, there is limited guidance on appropriate pain management in this population, and pharmacologic treatment can be harmful, leading to adverse outcomes, such as gastrointestinal bleeding ...
Alexis Holman, Neehar Parikh, Dan J. Clauw, David A. Williams, Elliot B. Tapper   +4 more
wiley   +1 more source

POSTURAL HYPOTENSION [PDF]

Heart, 1946
T, East, W, Brigden
openaire   +3 more sources

Female With Hypotension [PDF]

Annals of Emergency Medicine, 2021
Gordon Chien, Shilpa Kolli, Maninder Singh   +2 more
openaire   +3 more sources

Comparison of Metaraminol, Phenylephrine, and Norepinephrine Infusion for Prevention of Hypotension During Combined Spinal-Epidural Anaesthesia for Elective Caesarean Section: A Three-Arm, Randomized, Double-Blind, Non-Inferiority Trial

Drug Design, Development and Therapy, 2022
Youfa Zhou,1,* Yunyun Yu,1,2,* Miaofei Chu,1,3 Yanting Zhang,1 Xin Yu,1 Gang Chen1 1Department of Anesthesiology, Sir Run Run Shaw Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang, People’s Republic of China; 2Department of ...
Zhou Y, Yu Y, Chu M, Zhang Y, Yu X, Chen G   +5 more
doaj  

A Novel Two‐Part Mixture Model for the Incidence and Time Course of Cytokine Release Syndrome After Elranatamab Dosing in Multiple Myeloma Patients

Clinical Pharmacology &Therapeutics, EarlyView.
Cytokine release syndrome (CRS) is a common, acute adverse event associated with T‐cell redirecting therapies such as bispecific antibodies (BsAbs). The nature of CRS events data makes it challenging to capture an unbiased exposure–response relationship with commonly used models.
Donald Irby, Jennifer Hibma, Mohamed Elmeliegy, Diane Wang, Erik Vandendries, Kamrine Poels, Blerta Shtylla, Jason H. Williams   +7 more
wiley   +1 more source