Results 41 to 50 of about 3,363 (211)

Gelastic Epilepsy and Hypothalamic Hamartoma

Pediatric Neurology Briefs, 1999
The causes, clinical manifestations, and evolution of gelastic seizures (GS) were studied, using video-EEG and MRI, in 9 patients observed between 1986 and 1997 at the Epilepsy Center, Federico II University, Naples, Italy.
J Gordon Millichap
doaj   +1 more source

SV2A expression in blood cells as a possible biomarker candidate for levetiracetam treatment response

Epilepsia, EarlyView.
Abstract Objective This study was undertaken to evaluate whether synaptic vesicle protein 2A (SV2A) expression on peripheral immune cells predicts treatment response to levetiracetam in epilepsy. Methods High‐dimensional flow cytometry was used to prospectively assess SV2A expression on immune cells from levetiracetam responders, nonresponders, and ...
Johannes Lang, Mathias Linnerbauer, Jeanne Cuny, Veit Rothhammer, Hajo Hamer   +4 more
wiley   +1 more source

Hypothalamic Hamartoma and Sexual Precocity

Pediatric Neurology Briefs, 1990
Four boys with hypothalamic hamartomas associated with sexual precocity are reported from the Departments of Pediatrics and Neurosurgery, University of Pittsburgh, and the Department of Pediatrics, Johns Hopkins University School of Medicine, Baltimore ...
J Gordon Millichap
doaj   +1 more source

Central precocious puberty: From genetics to treatment [PDF]

, 2018
Central precocious puberty (CPP) results from early activation of the hypothalamic - pituitary -gonadal (HPG) axis and follows the same sequence as normal puberty.
Eugster, Erica A., Schneider Aguirre, Rebecca   +1 more
core   +1 more source

Mental health impacts experienced by caregivers of people with Dravet syndrome: A systematic literature review

Epilepsia, EarlyView.
Graphical abstract for the systematic literature review. Abstract Objective Dravet syndrome (DS) places tremendous burden on caregivers owing to the extent of required assistance and impact on daily living, as well as the risk to the individual with DS of premature mortality from sudden unexpected death in epilepsy and morbidity associated with ...
Adam Strzelczyk, Mary Anne Meskis, Galia Wilson, Bobby Jacob, Christoph Helmstaedter, Jane von Gaudecker, Veronica Hood, Ceri Hughes, Michael Scott Perry   +8 more
wiley   +1 more source

Gelastic Epilepsy and Hypothalamic Hamartoma

Pediatric Neurology Briefs, 2000
Three patients with small hypothalamic hamartomas and a recurrent “pressure to laugh,” often without actual laughter, are reported from the University of Melbourne, Australia, and McGill University, Canada.
J Gordon Millichap
doaj   +1 more source

Bird's-eye view of GnRH analog use in a pediatric endocrinology referral center [PDF]

, 2015
OBJECTIVE: Gonadotropin-releasing hormone analogs (GnRHa) are standard of care for the treatment of central precocious puberty (CPP). GnRHa have also been prescribed in other clinical settings with the hope of increasing adult stature, although ...
Eugster, Erica A., Greene, Ariana, Lewis, Katherine, Watson, Sara E.   +3 more
core   +1 more source

Epilepsy in emerging adulthood: Clinical, psychosocial, and surgical challenges

Epilepsia, EarlyView.
Abstract Objective Emerging adulthood (EAs; ages 19–29 years) is a unique developmental stage marked by major psychological, social, and occupational transitions. We sought to characterize the clinical, psychosocial, and surgical features of epilepsy in emerging adulthood, considering both current age and age at epilepsy onset.
Graham A. McLeod, Colin B. Josephson, Samuel Wiebe, The Calgary Comprehensive Epilepsy Program Collaborators, Felippe Borlot, Guillermo Delgado‐García, Paolo Federico, Nathalie Jette, Karl Martin Klein, William Murphy, Neelan Pillay, Andrea Salmon, Shaily Singh, The Epilepsy Surgery Satisfaction Questionnaire Study Group, Mark J. Atkinson, Walter J. Hader, Mark R. Keezer, Oluwaseyi A. Lawal, Sophia Macrodimitris, Kristina Malmgren, Dang K. Nguyen, Scott B. Patten, Tolulope T. Sajobi, Ruby Sharma, Yves Starreveld, José Tellez‐Zenteno, Sandra Wahby   +26 more
wiley   +1 more source

Direct resection is a safe and effective strategy to control seizures in patients with hypothalamic hamartoma

Scientific Reports
Achieving favorable seizure outcomes is challenging in patients with seizures resulting from hypothalamic hamartoma. Although minimally invasive and non-invasive surgical procedures are used to treat this population, these procedures have limitations ...
Yunwei Ou, Jingzhe Yuan, Chunde Li
doaj   +1 more source

Gelastic Epilepsy and Hypothalamic Hamartoma

Pediatric Neurology Briefs, 1997
Three patients with hypothalamic hamartoma and gelastic seizures were studied using ictal single-photon emission computed tomography and EEG recordings with depth electrodes at the University of Alabama at Birmingham Epilepsy Center.
J Gordon Millichap
doaj   +1 more source