Results 71 to 80 of about 3,363 (211)

Epilepsy: Molecular Pathogenesis and Emerging Therapies

MedComm, Volume 7, Issue 4, April 2026.
Progress has been made in the molecular pathogenesis of epilepsy, revealing multiple therapeutic targets. Recent advances in pharmacology, materials science, and surgical technique, coupled with progress in targeted therapy and disruptive epilepsy network technology, have led to the emergence of innovative strategies for epilepsy treatment.
Wanbin Huang, Jiabin Zong, Yu Zhang, Ming Li, Songqing Pan, Zheman Xiao   +5 more
wiley   +1 more source

Paediatric Epilepsy Surgery Programme in Hong Kong: experience in Queen Mary Hospital / Duchess of Kent Children's Hospital [PDF]

, 2009
Poster: no. P6BACKGROUND: Surgery is a well-established treatment for adults with intractable seizures. Increasingly, infants and children are being considered for epilepsy surgery.
Chan, PH, Fan, YW, Ho, WY, Hung, KN, Khong, PL, Mak, H, Wong, VCN, Yung, AWY   +7 more
core   +3 more sources

Hypothalamic hamartoma in adults

Chinese Journal of Contemporary Neurology and Neurosurgery, 2010
Objective To study the clinical features of hypothalamic hamartoma (HH) in adults. Methods A retrospective review of 27 cases of hypothalamic hamartoma in adults was performed, which account for 12.62% in all 214 hypothalamic hamartoma patients diagnosed
Chun⁃de LI, Shi⁃qi LUO, Zhen⁃yu MA, Yu⁃qi ZHANG, Ge JIA   +4 more
doaj  

Hypothalamic hamartoma in paediatric patients: Clinical characteristics, outcomes and review of the literature

Neurología (English Edition), 2012
Objective: To describe the epidemiological and clinical-electroencephalographic characteristics, and associated morbidity of patients with hypothalamic hamartoma, as well as the treatment followed and outcomes.
C. Castaño De La Mota, F. Martín Del Valle, A. Pérez Villena, M.L. Calleja Gero, R. Losada Del Pozo, M.L. Ruiz-Falcó Rojas   +5 more
doaj   +1 more source

Neural correlates of laughter and humour [PDF]

, 2017
Although laughter and humour have been constituents of humanity for thousands if not millions of years, their systematic study has begun only recently.
Grodd, Wolfgang, Rodden, Frank A., Ruch, Willibald, Wild, Barbara   +3 more
core  

Glomerulopathy in patients with distal duplication of chromosome 6p [PDF]

, 2016
Background: Duplication of the distal part of chromosome 6p is a rare genetic syndrome. Renal involvement has been reported in the majority of patients, including a wide range of congenital abnormalities of kidney and urinary tract and, occasionally, a ...
Bernaciak, Joanna, Bjerre, Anna, Jankauskienė, Augustina, Koczkowska, Magdalena, Lipska-Ziętkiewicz, Beata S., Schaefer, Franz   +5 more
core   +1 more source

Pathogenesis and potential therapeutic targets of trichorhinophalangeal syndrome; lessons obtained from animal studies

Developmental Dynamics, Volume 255, Issue 3, Page 228-245, March 2026.
Abstract Trichorhinophalangeal syndrome (TRPS) is a rare genetic disease inherited in an autosomal dominant manner. It occurs in 1 in 100,000 people globally and is caused by several types of mutations of the TRPS1 gene. Since the first human patient was reported in 1966, typical and atypical pathologies, disease courses, and treatment case ...
Naoya Saeki, Rinna Kanai, Sayuri Tatsuta, Shinichi Kawaguchi, Masatsune Itoh, Shinsuke Ohba, Makoto Abe   +6 more
wiley   +1 more source

Disabling amnestic syndrome following stereotactic laser ablation of a hypothalamic hamartoma in a patient with a prior temporal lobectomy

Epilepsy and Behavior Case Reports, 2015
A 19-year-old man with cortical dysplasia and intractable focal seizures underwent a right temporal lobectomy. A hypothalamic hamartoma was subsequently recognized, and he then underwent MRI-guided stereotactic laser ablation. Unfortunately, he sustained
Sarah Zubkov, Victor A. Del Bene, William S. MacAllister, Timothy M. Shepherd, Orrin Devinsky   +4 more
doaj   +1 more source

A implantação de eletrodos de profundidade na era da cirurgia guiada por imagem [PDF]

, 2011
The advent of modern image-guided surgery has revolutionized depth electrode implantation techniques. Stereoelectroencephalography (SEEG), introduced by Talairach in the 1950s, is an invasive method for three-dimensional analysis on the epileptogenic ...
Caboclo, Luís Otávio Sales Ferreira, Carrete Junior, Henrique, Cavalheiro, Sergio, Centeno, Ricardo Silva, Yacubian, Elza Márcia Targas   +4 more
core   +3 more sources

Areas of research priorities in epilepsy: A position paper of the European Reference Network for Rare and Complex Epilepsies, EpiCARE

Epilepsia Open, Volume 11, Issue 1, Page 291-321, February 2026.
Abstract Objective To define and articulate research priorities in epilepsy identified by the European Reference Network for Rare and Complex Epilepsies (ERN EpiCARE), addressing key unmet needs across the spectrum of rare and complex epilepsies. Methods This position paper was developed through a structured collaborative process involving patient ...
Sébile Tchaicha, Stéphane Auvin, Sándor Beniczky, Andreas Brunklaus, Lieven Lagae, Emilio Perucca, Rainer Surges, Sophie Adler, Christoph Helmstaedter, Floor Jansen, Guido Rubboli, Philippe Ryvlin, Nicola Specchio, Eugen Trinka, Ingmar Blümcke, Valentina de Giorgis, Katarzyna Kotulska, Gaetan Lesca, Masa Malenica, Amy McTague, Rima Nabbout, Rikke Steensbjerre Møller, Sandra Silva Arrieta, Isabella Brambilla, Małgorzata Kosla, Kees Braun, J. Helen Cross, Alexis Arzimanoglou   +27 more
wiley   +1 more source