Results 1 to 10 of about 68,919 (120)

The hypothalamic-pituitary-adrenal axis and the central monoaminergic systems: a pathophysiological link to insomnia with clinical implications [PDF]

Sleep Science, 2022
The authors present a theoretical overview of the hypothalamic-pituitary-adrenal axis and the central monoaminergic systems, focusing on a putative pathophysiological relationship to insomnia complaints.
Marcio Luciano de Souza Bezerra, Raimundo Nonato Delgado Rodrigues, Ricardo Oliveira Souza   +2 more
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Hypothalamic Perineuronal Nets Are Regulated by Sex and Dietary Interventions

Frontiers in Physiology, 2021
Perineuronal nets (PNNs) are widely present in the hypothalamus, and are thought to provide physical protection and ion buffering for neurons and regulate their synaptic plasticity and intracellular signaling.
Nan Zhang, Nan Zhang, Nan Zhang, Zili Yan, Hailan Liu, Meng Yu, Yang He, Hesong Liu, Chen Liang, Longlong Tu, Lina Wang, Na Yin, Junying Han, Nikolas Scarcelli, Yongjie Yang, Chunmei Wang, Tianshu Zeng, Tianshu Zeng, Lu-Lu Chen, Lu-Lu Chen, Yong Xu, Yong Xu   +21 more
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Arginine vasopressin in the medial amygdala causes greater post-stress recruitment of hypothalamic vasopressin neurons

Molecular Brain, 2021
Arginine vasopressin (AVP) is expressed in both hypothalamic and extra-hypothalamic neurons. The expression and role of AVP exhibit remarkable divergence between these two neuronal populations.
Wen Han Tong, Samira Abdulai-Saiku, Ajai Vyas   +2 more
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Heat Stress during Summer Attenuates Expression of the Hypothalamic Kisspeptin, an Upstream Regulator of the Hypothalamic–Pituitary–Gonadal Axis, in Domestic Sows

Animals, 2022
The release of reproductive hormones in the hypothalamic–pituitary–gonadal (HPG) axis is regulated by its upstream regulator, kisspeptin, and influenced by external stresses, including heat stress.
Hwan-Deuk Kim, Young-Jong Kim, Min Jang, Seul-Gi Bae, Sung-Ho Yun, Mi-Ree Lee, Yong-Ryul Seo, Jae-Keun Cho, Seung-Joon Kim, Won-Jae Lee   +9 more
doaj   +1 more source

Hypothalamic Contribution to Pituitary Functions Is Recapitulated In Vitro Using 3D-Cultured Human iPS Cells

Cell Reports, 2020
Summary: The pituitary is a major hormone center that secretes systemic hormones responding to hypothalamus-derived-releasing hormones. Previously, we reported the independent pituitary induction and hypothalamic differentiation of human embryonic stem ...
Takatoshi Kasai, Hidetaka Suga, Mayu Sakakibara, Chikafumi Ozone, Ryusaku Matsumoto, Mayuko Kano, Kazuki Mitsumoto, Koichiro Ogawa, Yu Kodani, Hiroshi Nagasaki, Naoko Inoshita, Mariko Sugiyama, Takeshi Onoue, Taku Tsunekawa, Yoshihiro Ito, Hiroshi Takagi, Daisuke Hagiwara, Shintaro Iwama, Motomitsu Goto, Ryoichi Banno, Jun Takahashi, Hiroshi Arima   +21 more
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Thyroid and Corticosteroid Signaling in Amphibian Metamorphosis

Cells, 2022
In multicellular organisms, development is based in part on the integration of communication systems. Two neuroendocrine axes, the hypothalamic–pituitary–thyroid and the hypothalamic–pituitary–adrenal/interrenal axes, are central players in orchestrating
Bidisha Paul, Zachary R. Sterner, Daniel R. Buchholz, Yun-Bo Shi, Laurent M. Sachs   +4 more
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Altered hypothalamic protein expression in a rat model of Huntington's disease. [PDF]

PLoS ONE, 2012
Huntington's disease (HD) is a neurodegenerative disorder, which is characterized by progressive motor impairment and cognitive alterations. Changes in energy metabolism, neuroendocrine function, body weight, euglycemia, appetite function, and circadian ...
Wei-na Cong, Huan Cai, Rui Wang, Caitlin M Daimon, Stuart Maudsley, Kerstin Raber, Fabio Canneva, Stephan von Hörsten, Bronwen Martin   +8 more
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Geoffrey Wingfield Harris (1913-1971), padre de la neuroendocrinología

Revista Colombiana de Endocrinología, Diabetes y Metabolismo, 2023
Background: The purpose of this narrative review is to highlight the work of Geoffrey W. Harris on the relationship between the hypothalamus and the pituitary gland, particularly the hypothalamic-pituitary-ovarian axis.
Alfredo Jacome-Roca
doaj   +1 more source

Hypothalamic AMP-Activated Protein Kinase as a Whole-Body Energy Sensor and Regulator [PDF]

Endocrinology and Metabolism
5´-Adenosine monophosphate (AMP)-activated protein kinase (AMPK), a cellular energy sensor, is an essential enzyme that helps cells maintain stable energy levels during metabolic stress. The hypothalamus is pivotal in regulating energy balance within the
Se Hee Min, Do Kyeong Song, Chan Hee Lee, Eun Roh, Min-Seon Kim   +4 more
doaj   +1 more source

Diet-Induced Obesity Elicits Macrophage Infiltration and Reduction in Spine Density in the Hypothalami of Male but Not Female Mice

Frontiers in Immunology, 2018
Increasing prevalence in obesity has become a significant public concern. C57BL/6J mice are prone to diet-induced obesity (DIO) when fed high-fat diet (HFD), and develop chronic inflammation and metabolic syndrome, making them a good model to analyze ...
Nancy M. Lainez, Carrie R. Jonak, Meera G. Nair, Iryna M. Ethell, Emma H. Wilson, Monica J. Carson, Djurdjica Coss   +6 more
doaj   +1 more source