Results 101 to 110 of about 202,089 (261)

Blood pressure effects of SGLT2 inhibitors and GLP‐1 receptor agonists: Mechanisms, trial evidence and Real‐world data

British Journal of Clinical Pharmacology, EarlyView.
SGLT2 inhibitors and GLP‐1 receptor agonists modestly lower blood pressure across diverse patient populations, including those without diabetes. These effects appear largely independent of glycaemic control and offer additive value in high‐risk patients with overlapping comorbidities.
Andrej Belančić, Yusuf Ziya Sener, Marijana Vučković, Joseph Edgar Blais, Almir Fajkić, Emina Sher, Mislav Radić, Josipa Radić   +7 more
wiley   +1 more source

Location of the hypothalamus

, 2016
A 3-D animation that shows the location of the hypothalamus in a mouse's brainComponente Curricular::Ensino Médio::BiologiaComponente Curricular::Educação Superior::Ciências da Saúde ...
Howard Hughes Medical Institute (HHMI)
core   +1 more source

Hypertension in obesity: A focus on individualized pharmacotherapy and the role of body composition, on behalf of the European Society of Hypertension Working Group on Diabetes and Metabolic Risk Factors and Working Group on Lifestyle, Cardiovascular Pharmacotherapy and Adherence

British Journal of Clinical Pharmacology, EarlyView.
Hypertension in obesity represents a major global health challenge, closely linked to the global epidemics of obesity, type 2 diabetes and metabolic dysfunction. Excess adiposity contributes to elevated blood pressure through multiple, interrelated mechanisms, including activation of the renin–angiotensin–aldosterone system, sympathetic nervous system ...
Christina Antza, Andrej Belancic, Jens Jordan, Alberto Esteban, Anna Oliveras, Ryan McNally, Panagiota Anyfanti, Jorie Versmissen, María S. Fernández‐Alfonso, Vasilios Kotsis, Thomas Weber, Alexandre Persu, Reinhold Kreutz   +12 more
wiley   +1 more source

Hypothalamic Neurochemical and Microglial Suppression in Long-Standing Human Hibernation-Like Syndrome. [PDF]

Neuropathol Appl Neurobiol
Jiang W, Kalsbeek A, Hut RA, Swaab DF, Yi CX.   +4 more
europepmc   +1 more source

The transmitters of the hypothalamus

, 1978
P. Skett, D. Ganten, L. Ferland, P. Eneroth, T. Hökfelt, O. Johansson, K. Andersson, S. I. Said, V. Mutt, K. Fuxe, J.-A. Gustafsson, Skett, P, Eneroth, P, Ferland, L, Ganten, D, Johansson, O, Gustafsson, J-A, Said, SI, Hökfelt, T, Andersson, K, Fuxe, K   +20 more
core   +1 more source

Histamine and the mechanisms of nausea and vomiting: Translating the uncertain pharmacology of cyclizine

British Journal of Clinical Pharmacology, EarlyView.
Abstract Cyclizine is a long‐established, short‐acting drug, registered for preventing motion sickness, post‐operative nausea and vomiting (PONV) and ‘vomiting of known cause’. The latter is not defined but may include pregnancy and patients receiving palliative care, historically accepted without large, controlled trials.
Gareth J. Sanger, Paul L. R. Andrews
wiley   +1 more source

Regulation of PACAP gene expression by ovarian sex steroids and kisspeptin: Study using hypothalamic cell lines and an <i>in vivo</i> female rat model. [PDF]

Biochem Biophys Rep
Tumurbaatar T, Oride A, Cairang Z, Okada H, Kanasaki H.   +4 more
europepmc   +1 more source

Neurovascular coupling in bone regeneration: Mechanisms, advanced biomaterials and challenges

BMEMat, EarlyView.
This figure illustrates various material strategies for neurovascularized bone regeneration, including electroactive scaffolds, ion‐loaded materials, drug delivery systems, surface modifications, cells/cell products, growth factors, and peptides. These approaches aim to synergistically promote the regeneration of neural, vascular, and bone tissues ...
Yixin Ma, Nan Jiang, Liyuan Chen, He Zhang, Xinjia Cai, Karan Gulati, Danqing He, Zhigang Cai, Yan Liu   +8 more
wiley   +1 more source

Functional analysis of adrenocorticotropic-hormone-producing pituitary cells derived from human pluripotent stem cells in murine and primate models of hypopituitarism. [PDF]

Stem Cell Res Ther
Kondo T, Suga H, Watari K, Taga S, Sakakibara M, Soen M, Kawamoto I, Nishida K, Emoto R, Shiraki Y, Hiroo S, Miwata T, Hirose T, Nagata Y, Takeuchi K, Nakano T, Ikeda A, Kuwahara A, Enomoto A, Tsuchiya H, Arima H, Saito R.   +21 more
europepmc   +1 more source

How developmental stressors affect mitochondrial respiratory function: a systematic review and meta‐analysis

Biological Reviews, EarlyView.
ABSTRACT The environmental conditions organisms experience during early development can have powerful and sustained effects on morphology, physiology, behaviour, and performance. Such developmental effects can influence reproductive success, survival, and life‐history strategies and can be transmitted across generations (i.e.
Ondi L. Crino, Christopher R. Friesen, Geoffrey E. Hill, Dalton C. Leibold, Pablo Recio, Karine Salin, Kristoffer H. Wild, Daniel W.A. Noble   +7 more
wiley   +1 more source