Results 121 to 130 of about 302,233 (277)

Multivariate Analysis of Hematological Stress Biomarkers and Welfare Domains in Organic and Intensive Pig Farming in Italy: A Pilot Study

open access: yesAnimal Research and One Health, EarlyView.
Intensive or organic farming systems may expose pigs to management or environmental challenges. Our preliminary results concluded that organic farming might enhance adaptive immune function, showing that improvements in welfare can translate into measurable immunological benefits, based on the correlation between welfare assessment and physiological ...
Dorotea Ippolito   +15 more
wiley   +1 more source

Glucocorticoid Alleviates Stress-induced Hypothalamic Nerve Injury by Inhibiting the GSDMD-dependent Pyroptosis Pathway

open access: yesJournal of Integrative Neuroscience
Background: Excessive stress leads to stress injury but the underlying mechanism is not completely understood and current preventive protocols are inadequate.
Shanyong Yi   +6 more
doaj   +1 more source

Expression of three GnRH receptors in specific tissues in male and female sea lampreys Petromyzon marinus at three distinct life stages [PDF]

open access: yes, 2013
Two recently cloned gonadotropin-releasing hormone (GnRH) receptors (lamprey GnRH-R-2 and lamprey GnRH-R-3) along with lamprey (l) GnRH-R-1 were shown to share similar structural features and amino acid motifs common to other vertebrate receptors.
Daukss, Dana M.   +3 more
core   +1 more source

SpartanAnatomy.org: Evaluating a new interactive neuroradiology tool for early medical education

open access: yesAnatomical Sciences Education, EarlyView.
Abstract Teaching neuroanatomy through the lens of magnetic resonance imaging (MRI) offers medical students a strong foundation for success. However, many existing MRI learning resources lack interactivity and user‐friendliness, require payment, or include an overwhelming number of labeled structures.
Halie Kerver   +3 more
wiley   +1 more source

Adverse Childhood Experiences in Autistic and Neurotypical Girls

open access: yesAutism Research, EarlyView.
ABSTRACT Adverse childhood experiences (ACEs) are potentially traumatic, life‐altering events that occur in childhood with long‐term negative physical and/or mental health outcomes. Previous research, while limited and largely focused on males, suggests children with autism spectrum disorder (ASD) are at higher risk of experiencing ACEs than typically ...
Jon Ebert   +4 more
wiley   +1 more source

The long-term impact of obesity in pregnancy on offspring hypothalamic feeding pathways

open access: yesRoyal Society Open Science
An accumulating body of evidence shows that offspring exposure to maternal obesity in the peri-natal period causes an increased risk to develop obesity later in life.
Pit Shan Chong, Laura Dearden
doaj   +1 more source

Blood pressure effects of SGLT2 inhibitors and GLP‐1 receptor agonists: Mechanisms, trial evidence and Real‐world data

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
SGLT2 inhibitors and GLP‐1 receptor agonists modestly lower blood pressure across diverse patient populations, including those without diabetes. These effects appear largely independent of glycaemic control and offer additive value in high‐risk patients with overlapping comorbidities.
Andrej Belančić   +7 more
wiley   +1 more source

Gene Expression of Feed Intake-Regulating Peptides in the Gut–Brain Axis of Laying Hens Housed Under Two Different Egg Production Systems

open access: yesAnimals
Intensive farming methods have improved productivity, but public concerns have arisen regarding the welfare of production animals, particularly laying hens, and consumers demand higher animal welfare standards in all animal production systems. This study
Kelly Johanna Lozano-Villegas   +3 more
doaj   +1 more source

Serotonin 5‐HT7 receptor signaling in neuropsychiatric disorders

open access: yesBulletin of the Korean Chemical Society, EarlyView.
5‐HT7R recruits Gs, G12, and β‐arrestin signaling to regulate neuronal plasticity, circuit function, and kinase‐linked intracellular responses. This review summarizes how these pathway‐selective modules contribute to autism spectrum disorder, depression, and schizophrenia, highlighting 5‐HT7R as a pathway‐informed therapeutic target. Abstract Serotonin
Eunseo Park, Hyunah Choo
wiley   +1 more source

Amygdala–hypothalamus–brainstem circuits underlying cardiovascular responses associated with the limits of high-intensity endurance exercise

open access: yesFrontiers in Physiology
In athletic competitions, athletes continually challenge the limits of human performance. Exercise limitation refers to a state in which fatigue accumulates during prolonged activity, preventing the maintenance of the required power output despite ...
Ko Yamanaka   +7 more
doaj   +1 more source

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