Results 171 to 180 of about 6,405,584 (270)

Evaluation of Transport Time on Stress Biomarkers in Pigs

open access: yesVeterinary Medicine and Science, Volume 11, Issue 5, September 2025.
The results of the study demonstrate that neither a transportation time of 1 h and 45 min (Group 1) nor a transportation time of 8 h (Group 2) has a negative impact on the animals. Serum cortisol was relatively unchanged, both between pre‐ and post‐transportation samples, as well as between groups. ABSTRACT Transportation of pigs may be associated with
Sarah Currie   +4 more
wiley   +1 more source

A Pilot Study to Evaluate the Effect of the Huiyangjiuzhen Acupuncture Technique on Dogs Recovering From Tiletamine–Zolazepam–Dexmedetomidine‐Induced Anaesthesia

open access: yesVeterinary Medicine and Science, Volume 11, Issue 5, September 2025.
Huiyangjiuzhen acupuncture technique (HAT) significantly improves the quality of recovery in dogs anaesthetised with tiletamine–zolazepam–dexmedetomidine. ABSTRACT Background Anaesthesia‐associated complications are problematic in veterinary practice; acupuncture can facilitate post‐anaesthesia recovery in dogs.
Yushuang Jian   +11 more
wiley   +1 more source

Treatment of Early‐Onset Specified and Unspecified Bipolar Disorders: A Systematic Review and Strategies for Identifying and Managing a Thermally Dysregulated Subtype in Children

open access: yesActa Psychiatrica Scandinavica, Volume 152, Issue 3, Page 156-179, September 2025.
ABSTRACT Introduction Bipolar disorder (BD), characterized by extreme mood shifts between mania and depression, can manifest in childhood, and pose treatment challenges. Treatment for full‐criteria BD I or II in children has been partially described in the literature, but major uncertainties exist regarding non‐classic presentations, which were ...
Demitri F. Papolos   +2 more
wiley   +1 more source

The effects of sleep deprivation on susceptibility to parasitic infection in Drosophila nigrospiracula

open access: yesPhysiological Entomology, Volume 50, Issue 3, Page 290-296, September 2025.
Sleep is important for cellular/humoral and behavioural immunity. In Drosophila mite systems, sleep deprivation reduced behavioural resistance against ectoparasitic infection. Sleep‐deprived flies exhibited lower endurance (negative geotaxis assay) and endurance is a reliable indicator of behavioural resistance against ectoparasites.
Holly Tang   +5 more
wiley   +1 more source

Novel 4,5‐Dihydrothiazole‐Phenylpiperazine Derivatives: Synthesis, Docking Studies and Pharmacological Evaluation as Serotonergic Agents

open access: yesChemMedChem, Volume 20, Issue 15, August 2, 2025.
The synthesis of a new series of 4,5‐dihydrothiazol‐2‐ylphenylpiperazine derivatives as serotoninergic ligands is described and tested for their affinity toward 5‐HT1A, 5‐HT2A,and 5‐HT2C and selected for further in vivo assays to determine their functional activity. The pharmacological studies highlight that among the developed derivatives, FG‐7 and FG‐
Giorgia Andreozzi   +18 more
wiley   +1 more source

AAVR Expression is Essential for AAV Vector Transduction in Sensory Hair Cells

open access: yesAdvanced Science, Volume 12, Issue 29, August 7, 2025.
Decreased sensitivity to AAV vector transduction in the outer hair cells (OHCs) of adult mice is primarily attributed to reduction of AAVR (Kiaa0319l; Au040320). Knockout of AAVR reduces AAV vector transduction efficiency in both inner hair cells (IHCs) and OHCs in neonatal mice.
Fan Wu   +8 more
wiley   +1 more source

Single Administration of AAV‐mAtp6v1b2 Gene Therapy Rescues Hearing and Vestibular Disorders Caused by Atp6v1b2‐Induced Lysosomal Dysfunction in Hair Cells

open access: yesAdvanced Science, Volume 12, Issue 29, August 7, 2025.
Wei et al. establish a hair cell‐specific conditional knockout mouse model (Atp6v1b2fl/fl;Atoh1Cre/+), and demonstrate the importance of Atp6v1b2 for hair cell through maintaining the survival of lysosomes. A single administration of AAV‐ie‐Eh3‐mAtp6v1b2 through scala media at P0‐P2 realizes function compensation and restores hearing and balance ...
Gege Wei   +15 more
wiley   +1 more source

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