Results 181 to 190 of about 3,614,670 (301)

Reduced cardiovascular mortality at moderate altitude: a putative role of physical activity and body mass

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Benefits of performing physical exercise at moderate altitude. At moderate altitude, increased resting metabolic rate and physical exertion promote physical fitness and exercise tolerance, whereas hypoxia suppresses appetite and elicits adaptations that increase tissue O2 delivery while augmenting O2‐independent ATP production ...
Robert T. Mallet   +6 more
wiley   +1 more source

Guanabenz induced hypothermia in a poisoned elderly female.

open access: yes, 1994
Guanabenz (Wytensin Wyeth-Ayerst Laboratories, Philadelphia, PA) is a centrally acting alpha 2 adrenergic agonist. Guanabenz shares structural and pharmacologic properties with the more commonly known sympatholytic agent clonidine.
Perrone, J   +3 more
core  

Scaling temporal resolution from mice to humans: Challenges and innovations in preclinical imaging of translational models

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Temporal scaling physiology differs significantly between mice and humans. Mice have higher metabolism, heart and respiratory rate, as well as faster blood flow rates, brain activity and physiological dynamics over time. These differences influence the temporal resolution needed in preclinical imaging of mouse models to ...
Sara Gargiulo, Matteo Gramanzini
wiley   +1 more source

Assessment of faecal calprotectin in neonatal calf diarrhoea using a human ELISA kit: Associations with faecal score and serum biochemical markers

open access: yesVeterinary Record Open, Volume 13, Issue 2, December 2026.
Abstract Background Diarrhoea in newborn calves, which occurs in the first month of life and is caused by various pathogens, poses a significant threat to livestock industries. Therefore, timely diagnosis of enteritis in calves can be advantageous. Objective This study aimed to determine the efficacy of faecal calprotectin as a biomarker indicating ...
Narges Lotfalizadeh   +3 more
wiley   +1 more source

Hypothalamic Neurochemical and Microglial Suppression in Long‐Standing Human Hibernation‐Like Syndrome

open access: yesNeuropathology and Applied Neurobiology, Volume 52, Issue 6, December 2026.
A rare case of a human hibernation‐like syndrome was associated with preserved hypothalamic anatomy but profound suppression of neuroendocrine and circadian neuropeptide systems. Marked reductions in synaptic and microglial immunoreactivity suggest a suppressed hypothalamic neuron–glial network, despite preserved astrocytic markers, myelination and ...
Wei Jiang   +4 more
wiley   +1 more source

Progenitor Timing Shapes NG2‐Glia Fate and Oligodendrocyte Differentiation

open access: yesGlia, Volume 74, Issue 11, November 2026.
Developmental timing defines NG2‐glia and oligodendrocyte fate. E16 NG2‐progenitors produce large, more dispersed NG2‐glia clones. P0 progenitors show a bias toward oligodendrocyte differentiation. Temporal windows establish long‐term cortical glial heterogeneity.
Ana Cristina Ojalvo‐Sanz   +2 more
wiley   +1 more source

The Potential for Absolute Temperature Imaging Based on Brain Metabolites Using an FID‐Shifting Approach in Gradient Echo Planar Spectroscopic Imaging (GREPSI)

open access: yesMagnetic Resonance in Medicine, Volume 96, Issue 5, Page 2044-2057, November 2026.
ABSTRACT Purpose To implement and evaluate an efficient method for absolute temperature measurement using a gradient echo implementation of the echo planar spectroscopic imaging (EPSI) sequence. Methods The gradient echo EPSI sequence (GREPSI) utilizes an oscillating readout gradient together with continuous signal readout after slab selective ...
Dennis L. Parker   +5 more
wiley   +1 more source

A Novel MR Elastography Device for Preclinical Applications From Spheroids to Rodents: Design, Validation, and Performance Evaluation

open access: yesNMR in Biomedicine, Volume 39, Issue 11, November 2026.
MR elastography (MRE) noninvasively assesses tissue biomechanics, but preclinical research suffers from diverse hardware solutions, hindering reproducibility and comparability. This study introduces a versatile preclinical MRE device for imaging rodents, ex vivo samples, and spheroids/organoids.
Gabrielle Mangin   +14 more
wiley   +1 more source

Environmental and systems‐based safety in the obstetric operating room: A narrative review

open access: yesPregnancy, Volume 2, Issue 6, November 2026.
Abstract Cesarean delivery requires an operating room (OR) that supports maternal surgery and anesthesia while preparing for fetal‐to‐newborn transition and, when needed, concurrent maternal and neonatal resuscitation. This narrative review applies a human factors framework to noise, information displays, medication and equipment organization, layout ...
Zoya Amer   +3 more
wiley   +1 more source

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