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A Case of Risperidone-Induced Hypothermia

American Journal of Therapeutics, 2004
Risperidone is one of the second-generation antipsychotics (SGAs). Use of SGAs or so-called atypical antipsychotics is becoming more frequent because they are more efficacious and safer than typical antipsychotics. This is due to their ability to occupy some other receptors as well as dopamine type 2 (D(2)) receptors in the brain.
Mohammad, Razaq, Muneeb, Samma
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MODIFICATION OF DRUG-INDUCED HYPOTHERMIA

Canadian Journal of Physiology and Pharmacology, 1964
Male albino rats, acclimated to 23 °C, were exposed to 2 °C and hypothermia was induced by means of reserpine, chlorpromazine, or noradrenaline. Pretreatment with imipramine, iproniazid, pargyline, or l-triiodothyronine of rats receiving reserpine resulted in better maintenance of metabolic rate and body temperature, and decreased mortality compared ...
H F, LETTAU, E A, SELLERS, E, SCHOENBAUM
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Mastoparan induces hypothermia in mice

Experientia, 1991
The polypeptide mastoparan, isolated from the venom of the Oriental Hornet, Vespa orientalis, induces hypothermia in white mice 15 minutes after its intraperitoneal injection. The hypothermic effect is induced by mastoparan obtained from different hornet and wasp venoms.
P, Duvdevani, J S, Ishay, A, Schejter
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On the mechanism(s) of morphine-induced hypothermia

Journal of Psychopharmacology, 1994
The effects of morphine on core body temperature of mice in the presence or absence of catecholamine receptor antagonists were examined. Administration of different doses of morphine (20, 30 and 40 mg/kg) to mice caused a hypothermic effect. Pre-treatment of animals with the opioid receptor antagonist naloxone (1, 1.5 and 3 mg/kg), the D-2 receptor ...
M R, Zarrindast   +3 more
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Meperidine-induced hypothermia in the rat

Neuropharmacology, 1982
A dose of 40 mg/kg of meperidine (pethidine) caused a marked lowering of rectal temperature in restrained female rats at room temperature (22 degrees C). This decrease was not antagonized by injection of 1 mg/kg of naloxone, whereas hypothermia of equal magnitude induced by 20 mg/kg of morphine was reversed by 1 mg/kg of naloxone. Pretreatment with the
P, McCleary, J D, Leander
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Ethanol-induced Hypothermia in the Rat

Pharmacology, 1980
Ethanol (0.5-3.2g x kg-1 i.p.) caused a dose-dependent fall in body temperature in rats. A dose of 1.5g x kg-1 i.p. led to a fall of 1.6 +/- 0.20 degrees C over 60 min at an environmental temperature of 18 +/- 1 degrees C. There was no evidence of acute tolerance when the hypothermic response was elicited by the same dose of ethanol (0.7--20.0g x kg-1 ...
P, Lomax   +3 more
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Phenitrone and marihuana induced hypothermia

Experientia, 1971
Le phenitrone, souvent considere comme antagoniste specifique de la marihuana, n'a non seulement pas empeche la baisse de temperature corporelle cause par la tetrahydrocannabinol (THC), mais potentialise l'effet hypothermique de cette derniere. Il est possible que cette potentialisation est par suite du deplacement de la THC localisee dans les ...
P, Lomax, C, Campbell
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Cholecystokinin-induced hypothermia in the rat

Experientia, 1981
Cholecystokinin-octapeptide (CCK-8) was shown to cause hypothermia after intracerebroventricular administration in the rat, and the hypothermic effect of CCK-8 was antagonized by simultaneous injection of TRH.
G, Katsuura, R, Hirota, S, Itoh
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Induced Hypothermia is Not "Artificial Hibernation"

JAMA: The Journal of the American Medical Association, 1966
The bleakness and chill of autumn evenings forewarns of the coming hostile winter season. Instinctively, a vast segment of the animal kingdom, unable to migrate to a more optimum biologic climate, prepares itself for survival. Through a variety of incredible methods, learned by each surviving species during millenniums of wintering experience, they ...
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