Grading the severity of hypoxic-ischemic encephalopathy in newborn EEG using a convolutional neural network [PDF]
Electroencephalography (EEG) is a valuable clinical tool for grading injury caused by lack of blood and oxygen to the brain during birth. This study presents a novel end-to-end architecture, using a deep convolutional neural network, that learns hierarchical representations within raw EEG data.
arxiv
PD149163 induces hypothermia to protect against brain injury in acute cerebral ischemic rats
Therapeutic hypothermia is a promising strategy for acute cerebral ischemia via physical or pharmacological methods. In this study, we pharmacologically induced hypothermia on Sprague Dawley rats by intraperitoneally injecting PD149163.
Teng-Fei Xue+7 more
doaj +1 more source
The Effect of Selective Hypothermia on Stroke Volume [PDF]
Hypothermia is a well-established neuroprotectant. Selective hypothermia to the ischemic area may eliminate side effects while improving induction time. We studied the effect of selective hypothermia on stroke volumes in adult domestic swine.
Mattingly, Thomas K
core +1 more source
Systemic hypothermia increases PAI-1 expression and accelerates microvascular thrombus formation in endotoxemic mice [PDF]
INTRODUCTION: Hypothermia during sepsis significantly impairs patient outcome in clinical practice. Severe sepsis is closely linked to activation of the coagulation system, resulting in microthrombosis and subsequent organ failure.
Klar, Ernst+3 more
core +2 more sources
The cold shock protein RBM3 can mediate mild hypothermia-related protection in neurodegeneration such as Alzheimer's disease. However, it remains unclear whether RBM3 and mild hypothermia provide same protection in model of Parkinson's disease (PD), the ...
Hai-Jie Yang+8 more
doaj +1 more source
Hypothermia protects the brain from transient global ischemia/reperfusion by attenuating endoplasmic reticulum response-induced apoptosis through CHOP. [PDF]
Endoplasmic reticulum (ER) stress has been implicated in the pathology of cerebral ischemia. Apoptotic cell death occurs during prolonged period of stress or when the adaptive response fails.
Xiaojie Liu+7 more
doaj +1 more source
An Empirical Study on Refactoring-Inducing Pull Requests [PDF]
Background: Pull-based development has shaped the practice of Modern Code Review (MCR), in which reviewers can contribute code improvements, such as refactorings, through comments and commits in Pull Requests (PRs). Past MCR studies uniformly treat all PRs, regardless of whether they induce refactoring or not.
arxiv
As a result of vitamin A abuse, excessive retinoic acid can induce apoptosis in neural cells. Mild-hypothermia and cold-inducible protein RBM3 protect neural cells from apoptosis.
Shuang-Ping Ma+12 more
doaj
Blood loss in primary total knee arthroplasty-body temperature is not a significant risk factor-a prospective, consecutive, observational cohort study [PDF]
BACKGROUND: Hypothermia related to anaesthesia and operating theatre environment is associated with increased blood loss in a number of surgical disciplines, including total hip arthroplasty.
Beller, Elaine+5 more
core +2 more sources
Nursing Frequency, Nursing Time, and Nursing Intervention Priorities depending on Neonatal Therapeutic Hypothermia Methods [PDF]
Purpose: This study compared nursing frequency, nursing time, and nursing intervention priorities depending on the method of neonatal induced hypothermia. Methods: We observed 15 neonatal subjects receiving therapeutic hypothermia for 3 days each.
Dong Yeon Kim+3 more
doaj +1 more source