Results 71 to 80 of about 153,410 (301)

Correlation Knowledge to Hypothermic Handling Practices in Students

South East Asia Nursing Research, 2021
Hypothermia is a decrease in core body temperature to
Dewi Sinta Windya Kustina
doaj   +1 more source

Progress and Application of Multifunctional Hydrogel in Radioactive Skin Injury

Advanced Materials Interfaces, EarlyView.
This review examines healing challenges in radiation‐wound injuries, where ionizing radiation impairs immune and tissue repair processes. Hydrogels, with their biocompatibility, antimicrobial properties, and drug delivery capabilities, present a transformative solution. It compares hydrogel efficacy in radiation‐induced versus common wounds, highlights
Xinyue Cui, Jingyi Wang, Xinyi Xu, Xiqian Cao, Yingtang Zhou, Jiaming Guo   +5 more
wiley   +1 more source

Cold blood perfusion for selective hypothermia in acute ischemic stroke

Brain Circulation, 2019
Hypothermia is the most reliably effective neuroprotectant, and yet systemic complications limit application. A large body of animal data suggests that hypothermia is effective for focal cerebral ischemia, namely acute ischemic stroke.
Thomas K Mattingly, Stephen P Lownie
doaj   +1 more source

Hypothermia for newborns with hypoxic-ischemic encephalopathy.

Paediatrics & child health, 2018
Therapeutic hypothermia is a standard of care for infants ≥36 weeks gestational age (GA) with moderate-to-severe hypoxic-ischemic encephalopathy. Because some studies included infants born at 35 weeks GA, hypothermia should be considered if they meet ...
B. Lemyre, Vann Chau
semanticscholar   +1 more source

Intrinsically Soft Implantable Electronics for Long‐term Biosensing Applications

Advanced Sensor Research, EarlyView.
Intrinsically soft implantable biosensors address the mechanical mismatch of conventional rigid implants, improving biocompatibility and stability. This review explores soft encapsulation matrices, stretchable conductors, implantation strategies, and chronic fixation techniques.
Su Hyeon Lee, Hyo Jin Lee, Sohye Lee, Dae‐Hyeong Kim, Hye Jin Kim, Sung‐Hyuk Sunwoo   +5 more
wiley   +1 more source

AAVR Expression is Essential for AAV Vector Transduction in Sensory Hair Cells

Advanced Science, EarlyView.
Decreased sensitivity to AAV vector transduction in the outer hair cells (OHCs) of adult mice is primarily attributed to reduction of AAVR (Kiaa0319l; Au040320). Knockout of AAVR reduces AAV vector transduction efficiency in both inner hair cells (IHCs) and OHCs in neonatal mice.
Fan Wu, Guisheng Chen, Rui Hu, Peiwen Liu, Jintao Lou, Wenji Zhao, Zuhong He, Suhua Sha, Yiqing Zheng   +8 more
wiley   +1 more source

Natural product P57 induces hypothermia through targeting pyridoxal kinase

Nature Communications, 2023
Induction of hypothermia during hibernation/torpor enables certain mammals to survive under extreme environmental conditions. However, pharmacological induction of hypothermia in most mammals remains a huge challenge.
Ruina Wang, Lei Xiao, Jianbo Pan, Guangsen Bao, Yunmei Zhu, Di Zhu, Jun Wang, Chengfeng Pei, Qinfeng Ma, Xian Fu, Ziruoyu Wang, Mengdi Zhu, Guoxiang Wang, Ling Gong, Qiuping Tong, Min Jiang, Junchi Hu, Miao He, Yun Wang, Tiejun Li, Chunmin Liang, Wei Li, Chunmei Xia, Zengxia Li, Dengke K. Ma, Minjia Tan, Jun Yan Liu, Wei Jiang, Cheng Luo, Biao Yu, Yongjun Dang   +30 more
doaj   +1 more source

Protection against cardiac ischemia-reperfusion injury by hypothermia and by inhibition of succinate accumulation and oxidation is additive

Basic Research in Cardiology, 2019
Hypothermia induced at the onset of ischemia is a potent experimental cardioprotective strategy for myocardial infarction. The aim of our study was to determine whether the beneficial effects of hypothermia may be due to decreasing mitochondria-mediated ...
M. Kohlhauer, V. Pell, N. Burger, A. Spiroski, A. Gruszczyk, J. Mulvey, Amin Mottahedin, Amin Mottahedin, Amin Mottahedin, Ana S. H. Costa, C. Frezza, B. Ghaleh, Michael P. Murphy, Michael P. Murphy, R. Tissier, T. Krieg   +15 more
semanticscholar   +1 more source

Single Administration of AAV‐mAtp6v1b2 Gene Therapy Rescues Hearing and Vestibular Disorders Caused by Atp6v1b2‐Induced Lysosomal Dysfunction in Hair Cells

Advanced Science, EarlyView.
Wei et al. establish a hair cell‐specific conditional knockout mouse model (Atp6v1b2fl/fl;Atoh1Cre/+), and demonstrate the importance of Atp6v1b2 for hair cell through maintaining the survival of lysosomes. A single administration of AAV‐ie‐Eh3‐mAtp6v1b2 through scala media at P0‐P2 realizes function compensation and restores hearing and balance ...
Gege Wei, Shiwei Qiu, Xue Gao, Lu Zheng, Yijin Chen, Ying Ma, Haifeng Feng, Jinyuan Yang, Guojie Dong, Huiyi Nie, Weihao Zhao, Xiaoge Li, Guangqin Wang, Wei Xiong, Pu Dai, Yongyi Yuan   +15 more
wiley   +1 more source

Outcomes of Hypothermia in Addition to Decompressive Hemicraniectomy in Treatment of Malignant Middle Cerebral Artery Stroke: A Randomized Clinical Trial

JAMA Neurology, 2019
Importance Moderate hypothermia in addition to early decompressive hemicraniectomy has been suggested to further reduce mortality and improve functional outcome in patients with malignant middle cerebral artery (MCA) stroke.
H. Neugebauer, H. Schneider, J. Bösel, C. Hobohm, S. Poli, R. Kollmar, J. Sobesky, S. Wolf, Miriam Bauer, S. Tittel, J. Beyersmann, J. Woitzik, Peter U. Heuschmann, E. Jüttler   +13 more
semanticscholar   +1 more source