Results 1 to 10 of about 16,203 (292)
Children, 2018 Hypotonic solutions have been used in pediatrics for maintenance of intravenous (IV) hydration. However, recent randomized control trials and cohort studies have raised significant concerns for association with hospital-acquired hyponatremia (HAH).
Spyridon A. Karageorgos +8 more
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Comparison of Serum Sodium Levels Following Intravenous Administration of Isotonic and Hypotonic Solutions in Young Children: A Randomized Controlled Trial [PDF]
Pediatric ReportsObjectives: This study evaluated changes in serum sodium (S Na) 24 h after the administration of isotonic versus hypotonic intravenous fluids (IVFs) and the incidences of dysnatremia and hyperchloremic metabolic acidosis.
Nisara Chongcharoen +3 more
doaj +2 more sources
From hypotonic maintenance fluid to severe hyponatremia: a case report
Journal of Medical Case Reports, 2021 Background The principles for maintenance intravenous fluid prescription in children were developed in the 1950s. These guidelines based on the use of hypotonic solutions have been challenged regularly for they seem to be associated with an increased ...
M. Denis +7 more
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Journal of Pharmacological Sciences, 2004 Contribution of inward rectifier K+ currents (IK1) and ATP-sensitive K+ currents (IKATP) to membrane potential changes of ventricular myocytes appearing during hypotonic challenge is unclear. We used here the whole cell patch clamp technique, voltage and
Ivan Kocic +2 more
doaj +2 more sources
Association Between Hyponatremia and Maintenance Intravenous Solutions in Critically Ill Children: A Retrospective Observational Study [PDF]
Frontiers in Pediatrics, 2021 Objetive: We sought to determine the association between maintenance intravenous solutions and the presence of hyponatremia in children in pediatric intensive care (PICU).Materials and Methods: An analytical observational study in children hospitalized ...
Jaime Fernández-Sarmiento +5 more
doaj +2 more sources
Avoiding hypotonic solutions in paediatrics: Keeping our patients safe. [PDF]
Paediatr Child Health, 2013 A previously healthy, fully immunized, 14 kg four-year-old girl presented to the local emergency department with a seven-day history of upper respiratory tract symptoms and 24 h of fever, irritability and decreased oral intake. Her temperature on presentation was 38.9°C, heart rate 120 beats/min, respiratory rate 25 breaths/min, and blood pressure 90 ...
Beck CE +6 more
europepmc +4 more sources
Memorias do Instituto Oswaldo Cruz, 1939 The writer reports experiments done with distilled water and hypotonic and hypertonic salt solutions of definite osmotic concentrations. The experiments were performed according to the Laewen-Trendelenburg technic using the vascular system of the frog's ...
Antonio Augusto Xavier
doaj +2 more sources
BMJ Paediatrics Open, 2019 Objective To compare the changes in serum sodium and acid/base status in patients receiving hypotonic and isotonic solutions.Design A randomised, controlled and double-blind clinical trial.Setting Department of Paediatrics in a tertiary general hospital (
Silvio Fabio Torres +5 more
doaj +2 more sources
PLoS ONE, 2020 BACKGROUND:In healthy children, an isotonic solution containing no glucose or a small amount of glucose (1-2%) has been recommended as an intraoperative maintenance fluid due to the potential risk of hyponatremia associated with hypotonic solutions ...
Mihyun Kim +5 more
doaj +2 more sources
Journal of Pharmacological Sciences, 2004 The aim of this study was to investigate the influence of hypotonic challenge on the effects of potassium channel openers (PCO), rilmakalim and pinacidil, on activation of the ATP-sensitive K+ current.
Ivan Kocić +2 more
doaj +2 more sources