Results 41 to 50 of about 1,864 (192)

Renal effects of uric acid: hyperuricemia and hypouricemia [PDF]

The Korean Journal of Internal Medicine, 2020
The prevalence of chronic kidney disease (CKD) is increasing worldwide. Although hyperuricemia has been associated with CKD in many studies, it remains controversial whether this is the cause or the result of decreased renal function.
Jung Hwan Park, Yong-Il Jo, Jong-Ho Lee
doaj   +1 more source

Xenotransplantation Literature Update: July–December 2025

Xenotransplantation, Volume 33, Issue 2, March/April 2026.
ABSTRACT The second half of 2025 marked a significant transition for xenotransplantation, shifting further from experimental feasibility to early clinical translation. Prolonged physiologic support from genetically engineered porcine kidneys and livers in human recipients provided unprecedented insight into organ compatibility, rejection dynamics, and ...
Kasra Shirini, Joseph M. Ladowski, Niket Harsh, Raphael P. H. Meier   +3 more
wiley   +1 more source

Acute Gout Flare After Carboplatin/5‐Fluorouracil for Locally Advanced Head and Neck Squamous Cell Carcinoma

Cancer Reports, Volume 9, Issue 2, February 2026.
ABSTRACT Background Head and neck squamous cell carcinoma (HNSCC) is the sixth most common cancer globally. For locally advanced cases when upfront surgery or radiation are not feasible, a platinum agent (carboplatin or cisplatin) with 5‐fluorouracil (carbo‐5FU) and immunotherapy is the standard of care.
Henry Zou, Anas Al Janadi, Zeyad Sako
wiley   +1 more source

The V‐Shaped Hamilton Receptors: A Paradigmatic Multipurpose Scaffold

ChemistryOpen, Volume 15, Issue 1, January 2026.
This manuscript explores the historical context and significance of molecular recognition in relation to Hamilton‐type receptors. It concludes with a discussion on future prospects for the development of novel functionalized Hamilton‐type receptors. It is hoped that this collection will offer new insights and directions for the supramolecular chemistry
Shafieq Ahmad Wagay, Rashid Ali
wiley   +1 more source

The Probable Cause of Hypouricemia; Xanthinuria

, 2019
Kalıtımsal hipoürisemiye genellikle ksantinüri ve herediter renal hipoürisemi yol açmaktadır. Hipoürisemi serum ürik asit seviyesinin 2mg/dl’den düşük olması olarak tanımlanmaktadır.
Ferhan CANDAN, Murat GÜLLÜ, Kazım ÖZTÜRK, Yılmaz CANIM, Öztürk, Kazım, Uçar, Edip, Güllü, Murat, Canım, Yılmaz, Can HÜZMELİ, CANIM, YILMAZ, Hüzmeli, Can, ÖZTÜRK, KAZIM, Edip UÇAR, Candan, Ferhan   +13 more
core   +1 more source

Controlled‐Release Nanoparticles for the Treatment of Childhood Refractory Epilepsy in Latin America

BioMed Research International, Volume 2026, Issue 1, 2026.
Childhood refractory epilepsy (CRE) remains a major therapeutic challenge in Latin America, where limited access to specialized care, persistent treatment gaps, and high rates of pharmacoresistance contribute to poor clinical outcomes. This review examines the potential of sol‐gel–derived silica and titania nanoparticles as controlled‐release platforms
Tessy López-Goerne, Abel Santamaria, Antonela Gonzalez-Bondani, Rafael Valiente, Francisco Osuna-Orozco, Natalia Beltrán-Peña, Dulce Gurgua   +6 more
wiley   +1 more source

DataSheet1_Identification of a dysfunctional exon-skipping splice variant in GLUT9/SLC2A9 causal for renal hypouricemia type 2.PDF

, 2023
Renal hypouricemia (RHUC) is a pathological condition characterized by extremely low serum urate and overexcretion of urate in the kidney; this inheritable disorder is classified into type 1 and type 2 based on causative genes encoding physiologically ...
Jaeho Yoon (211718), Yu Toyoda (2826734), Jana Bohatá (11108907), Anna Pallaiova (14434167), Velibor Tasic (191539), Jana Šaligová (14434170), Darryl Nousome (525651), Sung Kweon Cho (14434161), Victor A. David (14434164), Cheryl A. Winkler (7923875), Blanka Stibůrková (564063), Tappei Takada (2826728), Raul Cachau (14434173), Kateřina Pavelcová (9310184), Hiroshi Suzuki (8180)   +14 more
core   +1 more source

Hypouricemia in Chinese secondary hospital inpatients: a retrospective study on prevalence and determinants

European Journal of Medical Research
Purpose To investigate the prevalence of hypouricemia and explore its possible influencing factors in a secondary hospital. Patients and Methods This retrospective study included 17,541 adult inpatients at the Fusui County People’s Hospital (Guangxi ...
Quanxiang Li, Lijuan Gan, Lizhong Luo
doaj   +1 more source

Non-diabetic glycosuria as a diagnostic clue for acute tubulointerstitial nephritis in patients with azotemia

Renal Failure, 2020
Background Glycosuria is one of the manifestations of acute tubulointerstitial nephritis (ATIN), but may also be observed in other renal diseases. In this study, we investigated the value of non-diabetic glycosuria as a diagnostic clue for ATIN.
Taeyeon Lee, Won Seok Yang
doaj   +1 more source

Unraveling Fanconi Syndrome: Severe Proximal Tubulopathy, Osteomalacia in a 27‐Year‐Old Male on TDF‐Based HIV Regimen: A Case Report

Case Reports in Nephrology, Volume 2026, Issue 1, 2026.
This case report delves into the complex presentation of Fanconi syndrome (FS) associated with tenofovir disoproxil fumarate (TDF) use in a 27‐year‐old male diagnosed with HIV. The patient exhibited severe proximal tubulopathy and osteomalacia, emphasizing the need for vigilant monitoring in individuals on TDF‐based regimens.
Lavender Otom, Ben Lomatayo, Farida Kaittany, Priyanka Panwar, Ze’ev Korzets   +4 more
wiley   +1 more source