Results 111 to 120 of about 13,983 (221)

DNA Repair and Mutagenesis of ADP-Ribosylated DNA by Pierisin

Toxins
Pierisin is a DNA-targeting ADP-ribosyltransferase found in cabbage white butterfly (Pieris rapae). Pierisin transfers an ADP-ribosyl moiety to the 2-amino group of the guanine residue in DNA, yielding N2-(ADP-ribos-1-yl)-2′-deoxyguanosine (N2-ADPR-dG ...
Masanobu Kawanishi, Takashi Yagi, Yukari Totsuka, Keiji Wakabayashi   +3 more
doaj   +1 more source

New Targets for an Old Drug: A Chemical Proteomics Approach to Unraveling the Molecular Mechanism of Action of Methotrexate [PDF]

, 2004
Christopher M. Hosfield, Kelly Boutillier, Leroi Desouza, Leticia M. Toledo-Sherman, Linda Liao, Linda McBroom-Cerajewski, Michael F. Moran, Paul Taylor, Shane Climie   +8 more
core   +1 more source

Hypoxanthine-Guanine Phosphoribosyltransferase [PDF]

, 2020
openaire   +1 more source

Evaluation of purine-nucleoside degrading ability and in vivo uric acid lowering of Streptococcus thermophilus IDCC 2201, a novel antiuricemia strain.

PLoS ONE
This study evaluated 15 lactic acid bacteria with a focus on their ability to degrade inosine and hypo-xanthine-which are the intermediates in purine metabolism-for the management of hyperuricemia and gout.
Dayoung Kim, Jin Seok Moon, Ji Eun Kim, Ye-Ji Jang, Han Sol Choi, Ikhoon Oh   +5 more
doaj   +1 more source

Calcium Homeostasis in Escherichia coli: Characterization of Mutants and Genome Expression of MG1655 [PDF]

, 2014
While the role of calcium ions as secondary messengers has been well described in eukaryotic cells, little is known about calcium homeostasis in bacteria at the physiological and molecular levels.
Arif, Muhammad, Howard, Josh, Tisa, Louis S.   +2 more
core   +1 more source

Human Hypoxanthine-Guanine Phosphoribosyltransferase

Journal of Biological Chemistry, 1971
William J. Arnold, William N. Kelley
openaire   +1 more source

Molecular analysis of somatic mutations at the HPRT locus in lymphocytes of human population exposed to chronic high background natural radiation

Scientific Reports
Populations residing in high-level natural radiation areas (HLNRA) along the monazite-rich coastal belt of Kerala, India, are chronically exposed to low-dose ionizing radiation, with lifetime cumulative doses exceeding 1000 mGy.
Anila Gopinathan, Vinay Jain, Deepak Sharma, P. R. Vivek Kumar   +3 more
doaj   +1 more source

Study of HPRT gene expression using gene targeting and transgenic mice [PDF]

, 1989
(HPRT - Hypoxanthine-guanine Phosphoribosyltransferase)Available from British Library Document Supply Centre- DSC:D79294 / BLDSC - British Library Document Supply CentreSIGLEGBUnited ...
Thompson, Simon
core  

Crystal structures and inhibition of Trypanosoma brucei hypoxanthine-guanine phosphoribosyltransferase. [PDF]

Sci Rep, 2016
Terán D, Hocková D, Česnek M, Zíková A, Naesens L, Keough DT, Guddat LW.   +6 more
europepmc   +1 more source

Mutagenicity testing for chemical risk assessment: update of the WHO/IPCS Harmonized Scheme [PDF]

, 2017
Since the publication of the International Programme on Chemical Safety (IPCS) Harmonized Scheme for Mutagenicity Testing, there have been a number of publications addressing test strategies for mutagenicity.
Anderson, Diana, Anwar, Wagida A., Cimino, Michael C., Dobrev, Ivan, Douglas, George R., Eastmond, David A., Hartwig, Andrea, Nohmi, Takehiko, Phillips, David H., Vickers, Carolyn   +9 more
core