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Role of Human Hypoxanthine Guanine Phosphoribosyltransferase in Nucleotide Interconversion
1980It is well established that human Hypoxanthine-Guanine Phospho-ribosyltransferase (HGPRT, EC 2.4.2.8) catalyzes the reactions: Open image in new window Open image in new ...
GIACOMELLO, Alessandro +1 more
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1974
Partial deficiency of HGPRT, a salvage enzyme of purine metabolism, has been demonstrated to be the primary abnormality causing purine overproduction in a small proportion of patients with gout (1–4). The quantitative deviation in the activity of this enzyme has been shown by Kelley et al.
O, Sperling, P, Boer, A, De Vries
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Partial deficiency of HGPRT, a salvage enzyme of purine metabolism, has been demonstrated to be the primary abnormality causing purine overproduction in a small proportion of patients with gout (1–4). The quantitative deviation in the activity of this enzyme has been shown by Kelley et al.
O, Sperling, P, Boer, A, De Vries
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Biochemical and Biophysical Research Communications, 1967
W N, Kelley +3 more
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W N, Kelley +3 more
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Hypoxanthine-guanine phosphoribosyltransferase (HGPRT)
RCSB Protein Data Bank, 2012openaire +1 more source
[Hypoxanthine-guanine phosphoribosyltransferase deficiency].
Ryoikibetsu shokogun shirizu, 1998Y, Arai, N, Sakuragawa
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The crystal structure of human hypoxanthine-guanine phosphoribosyltransferase with bound GMP
Cell, 1994Giovanna Scapin
exaly
Hypoxanthine-guanine phosphoribosyltransferase deficiency.
Bulletin on the rheumatic diseases, 1971L B, Sorensen, P, Pepe
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