Results 111 to 120 of about 18,313 (167)
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Transformation of the gene for hypoxanthine phosphoribosyltransferase

Somatic Cell Genetics, 1979
Purified DNA from wild-type Chinese ovary (CHO) cells has been used to transform three hypoxanthine phosphoribosyltransferase (HPRT) deficient murine cell mutants to the enzyme positive state. Transformants appeared at an overall frequency of 5 x 10(-8) colonies/treated cell and expressed CHO HPRT activity as determined by electrophoresis.
L H, Graf, G, Urlaub, L A, Chasin
openaire   +2 more sources

Hypoxanthine nucleotides and muscular contraction

Biochimica et Biophysica Acta, 1963
Abstract 1. 1. Experiments have been devised to test the suggestion of a number of investigators that the interconversion of adenine and hypoxanthine nucleotides may provid the energy for muscular contraction. 2. 2. Several methods for the assay of very small amounts of these nucleotides in muscle extracts have been examined.
D F, CAIN, M J, KUSHMERICK, R E, DAVIES
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Transport of hypoxanthine by human diploid skin fibroblasts deficient in hypoxanthine-guanine phosphoribosyltransferase

Experimental Cell Research, 1977
Summary Transport of purine bases and nucleosides by a variety of mammalian cell lines is generally accomplished by facilitated diffusion, a non-concentrative, saturable process. However, previous investigators have been unable to detect a saturable component for the transport of hypoxanthine by human fibroblasts deficient in hypoxanthine-guanine ...
E, Murphy, M J, Holland, R P, Cox
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An amperometric hypoxanthine biosensor based on Au@FeNPs for determination of hypoxanthine in meat samples

International Journal of Biological Macromolecules, 2013
A xanthine oxidase (XOD) from buttermilk was immobilized covalently onto boronic acid functionalized gold coated iron nanoparticles (Au@FeNPs) electrodeposited on pencil graphite (PG) electrode, via the boroester linkages, between free hydroxyl groups of boronic acid, α-COOH and -NH2 groups of enzyme.
Rooma, Devi   +3 more
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Tautomeric Polymorph of Hypoxanthine from a Tautomeric Amorphous Hypoxanthine Precursor

Crystal Growth & Design
Abstract The nonclassical crystallization processes via amorphous precursors are one of the important principles in the organic biomineralization of guanine. Hypoxanthine is the second component in guanine biominerals. Amorphous hypoxanthine was synthesized for the first time via a neat ball-milling method, and a novel hypoxanthine ...
Yingying He   +3 more
openaire   +1 more source

Hypoxanthine

Exercise and Sport Sciences Reviews, 2015
Cardiorespiratory and biochemical indicators typically used by contemporary elite athletes seem to have limited applicability. According to some recent studies, purine metabolism better reflects exercise response and muscle adaptation in this group.
Jacek, Zieliński, Krzysztof, Kusy
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Uptake of Hypoxanthine in Human Erythrocytes

1977
The concentration of oxypurines in the plasma is known to be rather low (10 – 40 μM) (6). Since the formation of purines is accomplished to a great extent by the liver (7, 8), a transport of purines by erythrocytes from liver to tissues with limited or no capacity of de novo purine synthesis has been postulated (1, 3).
M M, Müller, G, Falkner
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The Spectrum of Hypoxanthine-guanine Phosphoribosyltransferase Deficiency

QJM: An International Journal of Medicine, 1973
Abstract The spectrum of clinical manifestations of hypoxanthine-guanine phosphoribosyltransferase (HGPRTase) deficiency is presented by reference to eight patients from five kindred. These patients illustrate the range of associated neurological findings, together with the variety of presentation and complications due to the ...
Emmerson, B. T., Thompson, L.
openaire   +4 more sources

Bimetallic Fe/Ni metal organic framework-based hypoxanthine biosensor for early monitoring of freshness changes of aquatic products.

Food Chemistry
The timely detection of freshness changes of aquatic products is crucial. In this study, we have developed a reliable, cost-effective, and user-friendly method for rapidly detecting hypoxanthine using a xanthine oxidase (XOD)/nanozyme enzymatic cascade ...
Zhuoran Li   +5 more
semanticscholar   +1 more source

Electrochemical oxidation of hypoxanthine

Journal of Electroanalytical Chemistry and Interfacial Electrochemistry, 1981
Abstract The electrochemical oxidation of hypoxanthine (6-oxypurine) in aqueous solution has been studied. The evidence strongly supports the view that hypoxanthine is initially electrooxidized in a 2 e −2H + reaction to give 6,8-dioxypurine. The latter compound is more easily oxidized than hypoxanthine and is immediately further electrooxidized to ...
Arnold C. Conway   +2 more
openaire   +1 more source

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