Results 121 to 130 of about 18,313 (167)

Hypoxanthine transport in human erythrocytes

Biochimica et Biophysica Acta (BBA) - Biomembranes, 1967
Abstract Using rapid sampling by filtration, it has been possible to follow and describe the transport of hypoxanthine across the human red blood cell membrane. The dependence of the transport rate upon the concentration of hypoxanthine is complex, and suggests a two-component mechanism. The first is a “saturable carrier system” with a K m of 0.
openaire   +2 more sources

Hypoxanthine–guanine phosphoribosyltransferase: further evidence for the identity of the binding sites for hypoxanthine and guanine

Canadian Journal of Biochemistry, 1969
Isotope exchange between hypoxanthine and both inosinate and guanylate, and between guanine and the same two ribonucleotides, support the view that hypoxanthine and guanine bind to the same site on hypoxanthine-guanine phosphoribosyltransferase.
openaire   +2 more sources

Synthesis of potential inhibitors of hypoxanthine-guaine phosphoribosyltransferase for testing as antiprotozoal agents. 2. 1-Substituted hypoxanthines.

Journal of Medicinal Chemistry, 1980
James R. Piper, Anne G. Laseter, T. P. Johnston, John A. Montgomery   +3 more
semanticscholar   +1 more source

Inhibition of purine nucleoside phosphorylase by 9-(phosphonoalkyl)hypoxanthines.

Biochemical Pharmacology, 1986
Charles E. Nakamura, Shih H. Chu, J. D. Stoeckler, Robert E. Parks   +3 more
semanticscholar   +1 more source

Oxidation of hypoxanthines, bearing 8-aryl or 8-pyridyl substituents, by bovine milk xanthine oxidase.

Biochimica et Biophysica Acta, 1977
F. Bergmann, Leon Levene, Hanna Govrin
semanticscholar   +1 more source

Programmable A-to-Y base editing by fusing an adenine base editor with an N-methylpurine DNA glycosylase

Nature Biotechnology, 2023
Huawei Tong, Xuchen Wang, Yuanhua Liu, Nana Liu, Yun Li, Jiamin Luo, Q. Ma, Danni Wu, Jiyong Li, Chun-Long Xu, Hui Yang   +10 more
semanticscholar   +1 more source

Hypoxanthine

2021
openaire   +1 more source

Ribosyl derivatives of hypoxanthine

The Journal of Organic Chemistry, 1969
J A, Montgomery, H J, Thomas
openaire   +2 more sources

The structures of polyinosinic acid

Biophysik, 1973
Danielle Thiele, W. Guschlbauer
semanticscholar   +1 more source

Hypoxanthine: a marker for asphyxia.

Obstetrics and gynecology, 1988
It has been hypothesized that hypoxanthine concentrations in the blood of newborn infants are a marker of asphyxia. To test this hypothesis, we measured serum hypoxanthine levels in relationship to perinatal and neonatal asphyxia, and compared arterial hypoxanthine levels with arterial pH and base deficit.
J, Pietz, N, Guttenberg, L, Gluck
openaire   +1 more source