Results 121 to 130 of about 530 (169)
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Pediatrics, 1991
The study by Rognum and Saugstad concerning elevated hypoxanthine levels in the vitreous humor of victims of Sudden Infant Death Syndrome (SIDS) made a laudable attempt to correct for postmortem increases in this marker of hypoxia, but I am concerned that the authors have not sufficiently recognized some characteristics of SIDS that could have ...
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The study by Rognum and Saugstad concerning elevated hypoxanthine levels in the vitreous humor of victims of Sudden Infant Death Syndrome (SIDS) made a laudable attempt to correct for postmortem increases in this marker of hypoxia, but I am concerned that the authors have not sufficiently recognized some characteristics of SIDS that could have ...
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Transformation of the gene for hypoxanthine phosphoribosyltransferase
Somatic Cell Genetics, 1979Purified DNA from wild-type Chinese ovary (CHO) cells has been used to transform three hypoxanthine phosphoribosyltransferase (HPRT) deficient murine cell mutants to the enzyme positive state. Transformants appeared at an overall frequency of 5 x 10(-8) colonies/treated cell and expressed CHO HPRT activity as determined by electrophoresis.
L H, Graf, G, Urlaub, L A, Chasin
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Hypoxanthine nucleotides and muscular contraction
Biochimica et Biophysica Acta, 1963Abstract 1. 1. Experiments have been devised to test the suggestion of a number of investigators that the interconversion of adenine and hypoxanthine nucleotides may provid the energy for muscular contraction. 2. 2. Several methods for the assay of very small amounts of these nucleotides in muscle extracts have been examined.
D F, CAIN, M J, KUSHMERICK, R E, DAVIES
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Experimental Cell Research, 1977
Summary Transport of purine bases and nucleosides by a variety of mammalian cell lines is generally accomplished by facilitated diffusion, a non-concentrative, saturable process. However, previous investigators have been unable to detect a saturable component for the transport of hypoxanthine by human fibroblasts deficient in hypoxanthine-guanine ...
E, Murphy, M J, Holland, R P, Cox
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Summary Transport of purine bases and nucleosides by a variety of mammalian cell lines is generally accomplished by facilitated diffusion, a non-concentrative, saturable process. However, previous investigators have been unable to detect a saturable component for the transport of hypoxanthine by human fibroblasts deficient in hypoxanthine-guanine ...
E, Murphy, M J, Holland, R P, Cox
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International Journal of Biological Macromolecules, 2013
A xanthine oxidase (XOD) from buttermilk was immobilized covalently onto boronic acid functionalized gold coated iron nanoparticles (Au@FeNPs) electrodeposited on pencil graphite (PG) electrode, via the boroester linkages, between free hydroxyl groups of boronic acid, α-COOH and -NH2 groups of enzyme.
Rooma, Devi +3 more
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A xanthine oxidase (XOD) from buttermilk was immobilized covalently onto boronic acid functionalized gold coated iron nanoparticles (Au@FeNPs) electrodeposited on pencil graphite (PG) electrode, via the boroester linkages, between free hydroxyl groups of boronic acid, α-COOH and -NH2 groups of enzyme.
Rooma, Devi +3 more
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Exercise and Sport Sciences Reviews, 2015
Cardiorespiratory and biochemical indicators typically used by contemporary elite athletes seem to have limited applicability. According to some recent studies, purine metabolism better reflects exercise response and muscle adaptation in this group.
Jacek, Zieliński, Krzysztof, Kusy
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Cardiorespiratory and biochemical indicators typically used by contemporary elite athletes seem to have limited applicability. According to some recent studies, purine metabolism better reflects exercise response and muscle adaptation in this group.
Jacek, Zieliński, Krzysztof, Kusy
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Uptake of Hypoxanthine in Human Erythrocytes
1977The concentration of oxypurines in the plasma is known to be rather low (10 – 40 μM) (6). Since the formation of purines is accomplished to a great extent by the liver (7, 8), a transport of purines by erythrocytes from liver to tissues with limited or no capacity of de novo purine synthesis has been postulated (1, 3).
M M, Müller, G, Falkner
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The Spectrum of Hypoxanthine-guanine Phosphoribosyltransferase Deficiency
QJM: An International Journal of Medicine, 1973The spectrum of clinical manifestations of hypoxanthine-guanine phosphoribosyltransferase (HGPRTase) deficiency is presented by reference to eight patients from five kindred. These patients illustrate the range of associated neurological findings, together with the variety of presentation and complications due to the associated over-production of urate.
Emmerson, B. T., Thompson, L.
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Electrochemical oxidation of hypoxanthine
Journal of Electroanalytical Chemistry and Interfacial Electrochemistry, 1981Abstract The electrochemical oxidation of hypoxanthine (6-oxypurine) in aqueous solution has been studied. The evidence strongly supports the view that hypoxanthine is initially electrooxidized in a 2 e −2H + reaction to give 6,8-dioxypurine. The latter compound is more easily oxidized than hypoxanthine and is immediately further electrooxidized to ...
Arnold C. Conway +2 more
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Hypoxanthine transport in human erythrocytes
Biochimica et Biophysica Acta (BBA) - Biomembranes, 1967Abstract Using rapid sampling by filtration, it has been possible to follow and describe the transport of hypoxanthine across the human red blood cell membrane. The dependence of the transport rate upon the concentration of hypoxanthine is complex, and suggests a two-component mechanism. The first is a “saturable carrier system” with a K m of 0.
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