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Electrochemical reduction of alloxan, methyl- and dimethyl alloxan in aqueous and acetonitrile solutions. [PDF]
Hansen, Barbara Helen,
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L-arginine metabolism inhibits arthritis and inflammatory bone loss. [PDF]
Cao S+18 more
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Reversal of Pulmonary Hypertension in a Human-Like Model: Therapeutic Targeting of Endothelial DHFR. [PDF]
Murugesan P+8 more
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Synthesis and preliminary biological evaluation of furo- and oxazolopyrimidines [PDF]
De Coen, Laurens
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Plasma Hypoxanthine and Exercise
American Review of Respiratory Disease, 1987During exercise, ATP is converted to ADP and AMP to supply energy for muscular contraction. It is then regenerated via various pathways of intermediary metabolism. However, with high levels of exercise, net ATP degradation in muscle occurs. In exercise and other clinical situations, adenine nucleotide degradation leads to an accumulation of degradative
Richard Simon+3 more
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On the interaction of hypoxanthine with adenine
Experientia, 1967Une conversion non-enzymatique d'hypoxanthine en adenine fut proposee sur la base d'observations spectrophotometriques obtenues de solutions contenant adenine et hypoxanthine dans 1–5M de phosphate d'ammonium. Les resultats fournis par les experiences sur la radioactivite ne confirme pas la conclusion emise parBowne2 que hypoxanthine et adenine ...
J. Ludowieg, J. D. Benmaman
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Biochemical Medicine, 1973
Abstract Hypoxanthine transport has been studied in cultured human fibroblasts with normal and mutant H-G PRT. Transport is dependent on cell density, the activity of H-G PRT, and de novo purine synthesis. Transport is decreased in control cultures at high density and in cell strains with a mutant H-G PRT.
Norma Herrick+2 more
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Abstract Hypoxanthine transport has been studied in cultured human fibroblasts with normal and mutant H-G PRT. Transport is dependent on cell density, the activity of H-G PRT, and de novo purine synthesis. Transport is decreased in control cultures at high density and in cell strains with a mutant H-G PRT.
Norma Herrick+2 more
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Hypoxanthine Phosphoribosyltransferase and Hypoxanthine Uptake in Human Erythrocytes
Hoppe-Seyler´s Zeitschrift für physiologische Chemie, 1975A system of hypoxanthine uptake and IMP retention was studied and characterized in human erythrocytes. It follows closely the system already described for rabbit erythrocytes[7]. IMP formation and retention are dependent on the activity of hypoxanthine phosphoribosyl-transferase and on intracellular availability of phosphoribosyl pyrophosphate (P-Rib ...
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Transformation of the gene for hypoxanthine phosphoribosyltransferase [PDF]
Purified DNA from wild-type Chinese ovary (CHO) cells has been used to transform three hypoxanthine phosphoribosyltransferase (HPRT) deficient murine cell mutants to the enzyme positive state. Transformants appeared at an overall frequency of 5 x 10(-8) colonies/treated cell and expressed CHO HPRT activity as determined by electrophoresis.
Lawrence A. Chasin+2 more
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