Results 141 to 150 of about 579 (178)

L-arginine metabolism inhibits arthritis and inflammatory bone loss. [PDF]

open access: yesAnn Rheum Dis
Cao S   +18 more
europepmc   +1 more source

Reversal of Pulmonary Hypertension in a Human-Like Model: Therapeutic Targeting of Endothelial DHFR. [PDF]

open access: yesCirc Res
Murugesan P   +8 more
europepmc   +1 more source

Plasma Hypoxanthine and Exercise

American Review of Respiratory Disease, 1987
During exercise, ATP is converted to ADP and AMP to supply energy for muscular contraction. It is then regenerated via various pathways of intermediary metabolism. However, with high levels of exercise, net ATP degradation in muscle occurs. In exercise and other clinical situations, adenine nucleotide degradation leads to an accumulation of degradative
Richard Simon   +3 more
openaire   +2 more sources

On the interaction of hypoxanthine with adenine

Experientia, 1967
Une conversion non-enzymatique d'hypoxanthine en adenine fut proposee sur la base d'observations spectrophotometriques obtenues de solutions contenant adenine et hypoxanthine dans 1–5M de phosphate d'ammonium. Les resultats fournis par les experiences sur la radioactivite ne confirme pas la conclusion emise parBowne2 que hypoxanthine et adenine ...
J. Ludowieg, J. D. Benmaman
openaire   +3 more sources

Transport of hypoxanthine in fibroblasts with normal and mutant hypoxanthine-guanine phosphoribosyltransferase

Biochemical Medicine, 1973
Abstract Hypoxanthine transport has been studied in cultured human fibroblasts with normal and mutant H-G PRT. Transport is dependent on cell density, the activity of H-G PRT, and de novo purine synthesis. Transport is decreased in control cultures at high density and in cell strains with a mutant H-G PRT.
Norma Herrick   +2 more
openaire   +3 more sources

Hypoxanthine Phosphoribosyltransferase and Hypoxanthine Uptake in Human Erythrocytes

Hoppe-Seyler´s Zeitschrift für physiologische Chemie, 1975
A system of hypoxanthine uptake and IMP retention was studied and characterized in human erythrocytes. It follows closely the system already described for rabbit erythrocytes[7]. IMP formation and retention are dependent on the activity of hypoxanthine phosphoribosyl-transferase and on intracellular availability of phosphoribosyl pyrophosphate (P-Rib ...
openaire   +3 more sources

Transformation of the gene for hypoxanthine phosphoribosyltransferase [PDF]

open access: possibleSomatic Cell Genetics, 1979
Purified DNA from wild-type Chinese ovary (CHO) cells has been used to transform three hypoxanthine phosphoribosyltransferase (HPRT) deficient murine cell mutants to the enzyme positive state. Transformants appeared at an overall frequency of 5 x 10(-8) colonies/treated cell and expressed CHO HPRT activity as determined by electrophoresis.
Lawrence A. Chasin   +2 more
openaire   +2 more sources

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