Results 151 to 160 of about 579 (178)
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SLC23A3 is a renal hypoxanthine transporter
Nucleosides, Nucleotides & Nucleic Acids, 2022LLC-PK1 renal cells show Na+-dependent and Na+-independent hypoxanthine uptake. While the latter is inhibited by adenine, neither are inhibited by xanthine. In rats, intestinal Na+-dependent hypoxanthine transporter Slc23a4 is not expressed in the kidney, and its action is inhibited by xanthine.
Makoto Hosoyamada +5 more
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Electrochemical oxidation of hypoxanthine
Journal of Electroanalytical Chemistry and Interfacial Electrochemistry, 1981Abstract The electrochemical oxidation of hypoxanthine (6-oxypurine) in aqueous solution has been studied. The evidence strongly supports the view that hypoxanthine is initially electrooxidized in a 2 e −2H + reaction to give 6,8-dioxypurine. The latter compound is more easily oxidized than hypoxanthine and is immediately further electrooxidized to ...
Glenn Dryhurst +2 more
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Facilitated Purification of Hypoxanthine Phosphoribosyltransferase
Hoppe-Seyler´s Zeitschrift für physiologische Chemie, 1976Three major approaches to the complete purification of hypoxanthine phosphoribosyltransferase from human erythrocytes and rat brain are described. Preparative isoelectric focusing which has been used for the isolation of the human enzyme was not fully successful in the case of rat brain.
Marianne Huber +2 more
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Hypoxanthine in cerebrospinal fluid in children
Scandinavian Journal of Clinical and Laboratory Investigation, 1978In forty-five children the hypoxanthine concentration in cerebrospinal fluid (CSF) was measured (fifty-two samples). In newborn infants (nineteen patients) the hypoxanthine levels were higher in patients with clinical conditions associated with hypoxia (idiopathic respiratory distress syndrome, asphyxia, apneic attacks) than in patients without ...
Alf Meberg, Ola Didrik Saugstad
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Hypoxanthine nucleotides and muscular contraction
Biochimica et Biophysica Acta, 1963Abstract 1. 1. Experiments have been devised to test the suggestion of a number of investigators that the interconversion of adenine and hypoxanthine nucleotides may provid the energy for muscular contraction. 2. 2. Several methods for the assay of very small amounts of these nucleotides in muscle extracts have been examined.
Robert E. Davies +2 more
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Experimental Cell Research, 1977
Summary Transport of purine bases and nucleosides by a variety of mammalian cell lines is generally accomplished by facilitated diffusion, a non-concentrative, saturable process. However, previous investigators have been unable to detect a saturable component for the transport of hypoxanthine by human fibroblasts deficient in hypoxanthine-guanine ...
Rody P. Cox, M.J. Holland, Ellen Murphy
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Summary Transport of purine bases and nucleosides by a variety of mammalian cell lines is generally accomplished by facilitated diffusion, a non-concentrative, saturable process. However, previous investigators have been unable to detect a saturable component for the transport of hypoxanthine by human fibroblasts deficient in hypoxanthine-guanine ...
Rody P. Cox, M.J. Holland, Ellen Murphy
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Hypoxanthine Transport in Human Erythrocytes
1980De novo synthesis of purines does not appear to take place in mature human erythrocytes because the enzymes for the pathway are absent1. Therefore purine bases should be normally have to be supplied exogenously to erythrocytes.
GIACOMELLO, Alessandro +1 more
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Hypoxanthine transport in human erythrocytes
Biochimica et Biophysica Acta (BBA) - Biomembranes, 1967Abstract Using rapid sampling by filtration, it has been possible to follow and describe the transport of hypoxanthine across the human red blood cell membrane. The dependence of the transport rate upon the concentration of hypoxanthine is complex, and suggests a two-component mechanism. The first is a “saturable carrier system” with a K m of 0.
Ulrik V. Lassen, Ulrik V. Lassen
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Automated Analysis of Hypoxanthine
Journal of Food Science, 1965SUMMARYHypoxanthine concentration is a useful index of the quality of flesh foods. A rapid manual assay of the purine was automated by modifying commercially available proportioning and spectrophotometric equipment. Extracts are sampled serially and mixed with xanthine oxidase and buffer.
J. Murray, J. R. Burt, N. R. Jones
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International Journal of Biological Macromolecules, 2013
A xanthine oxidase (XOD) from buttermilk was immobilized covalently onto boronic acid functionalized gold coated iron nanoparticles (Au@FeNPs) electrodeposited on pencil graphite (PG) electrode, via the boroester linkages, between free hydroxyl groups of boronic acid, α-COOH and -NH2 groups of enzyme.
Rooma Devi +3 more
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A xanthine oxidase (XOD) from buttermilk was immobilized covalently onto boronic acid functionalized gold coated iron nanoparticles (Au@FeNPs) electrodeposited on pencil graphite (PG) electrode, via the boroester linkages, between free hydroxyl groups of boronic acid, α-COOH and -NH2 groups of enzyme.
Rooma Devi +3 more
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