Results 71 to 80 of about 579 (178)

Antioxidant supplementation blunts the proteome response to 3 weeks of sprint interval training preferentially in human type 2 muscle fibres

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Sprint interval training (SIT) is a popular time‐efficient type of endurance training. Healthy young men performed nine SIT sessions (4–6 × 30 s all‐out cycling sprints) over 3 weeks while being supplemented with antioxidants (high doses of vitamins C and E) or placebo. Muscle biopsies taken before and after the first SIT session
Victoria L. Wyckelsma   +12 more
wiley   +1 more source

Purine Chemistry in the Early RNA World at the Origins of Life: From RNA and Nucleobases Lesions to Current Key Metabolic Routes

open access: yesChemBioChem, Volume 26, Issue 11, June 3, 2025.
In the nascent processes of the beginnings and evolution of life, nucleobases and especially purines, ribonucleos(t)ides and primitive RNAs have been continuously modified. A RNA‐peptide world and key metabolic pathways probably have emerged from the corresponding chemical modifications resulting from adenine deamination, purine alkylation and ...
Jean‐Luc Décout   +1 more
wiley   +1 more source

Exploring the Healing Potential of Aqueous Extract of Baccaurea ramiflora Leaves in Inflammation: A Cytokine and Prostaglandin Modulator

open access: yesFood Science &Nutrition, Volume 13, Issue 6, June 2025.
This study demonstrates that the aqueous extract of Baccaurea ramiflora leaves (BrLAE) possesses significant antioxidant and anti‐inflammatory properties. BrLAE treatment effectively reduced CFA‐induced paw edema, improved hematological and biochemical parameters, and downregulated pro‐inflammatory gene expression in Wistar rats.
Muhammad Nasir Hayat Malik   +11 more
wiley   +1 more source

Sex‐specific associations of Roseburia with uric acid metabolism and hyperuricemia risk in females

open access: yesiMetaOmics, Volume 2, Issue 2, June 2025.
Researchers recruited 623 participants, including 270 females, and used 16S rDNA sequencing to investigate gender differences in hyperuricemia. In healthy females, Roseburia was enriched, positively correlating with estrogen and negatively with uric acid, suggesting it is a potential biomarker affecting uric acid levels in females.
Zhihan Yang   +8 more
wiley   +1 more source

A Retrospective Look at the Impact of Binding Site Environment on the Optimization of TRPA1 Antagonists. [PDF]

open access: yesACS Med Chem Lett, 2021
Villemure E   +9 more
europepmc   +1 more source

The Role of Metabolic Testing in the Diagnostic Evaluation of Adult NORSE: A Retrospective, Single‐Centre Study

open access: yesEuropean Journal of Neurology, Volume 32, Issue 6, June 2025.
ABSTRACT Background New‐onset refractory status epilepticus (NORSE) is a diagnostically challenging and severe epileptic presentation in which aetiology is an important predictor of outcome. This retrospective study aimed to investigate the utility of metabolic screening to determine the underlying cause in 42 patients with suspected NORSE, admitted to
Jennifer Kilmer   +6 more
wiley   +1 more source

Anti-inflammatory potential of Penicillium brefeldianum endophytic fungus supported with phytochemical profiling. [PDF]

open access: yesMicrob Cell Fact, 2023
Saleh A   +9 more
europepmc   +1 more source

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