Results 151 to 160 of about 649,237 (386)
Ekspresi Relatif MRNA Hypoxia Inducible Factor-1? Pada Sel Glioma Penderita [PDF]
, 2013 Glioma merupakan tumor otak primer yang cukup sering ditemukan di Indonesia di antara keganasan otak lainnya. Penderita glioma mempunyai angka harapan hidup yang rendah dikarenakan seringnya mengalami resistansi terapi.
Hardiany, N. S. (Novi) +2 more
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Advanced Functional Materials, EarlyView.A hydrogel for intra‐articular injection for the treatment of rheumatoid arthritis (RA) is formulated and comprehensively studied. After administration, the hydrogel induces a metabolic reprogramming of immunometabolism of macrophages to trigger fatty acid oxidation subsequently inducing polarization of anti‐inflammatory M2 macrophages. This results in
Yutong Song +8 more
wiley +1 more source
Progress toward overcoming hypoxia-induced resistance to solid tumor therapy
Cancer Management and Research, 2015 Sergey V Karakashev, Mauricio J Reginato Department of Biochemistry and Molecular Biology, Drexel University College of Medicine, Philadelphia, PA, USA Abstract: Hypoxic tumors are associated with poor clinical outcome for multiple types of human cancer.
Karakashev SV, Reginato MJ
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Age-dependent Defect in Vascular Endothelial Growth Factor Expression Is Associated with Reduced Hypoxia-inducible Factor 1 Activity [PDF]
, 2000 Alain Rivard +7 more
openalex +1 more source
A Vertically‐Stacked Optoelectronic Sensor for Localized Hemodynamics Monitoring
Advanced Functional Materials, EarlyView.This work introduces a hemodynamics monitoring sensor that features vertically stacked microLEDs and a heterogeneously integrated photodetector. The vertically stacked microLEDs enable localized measurements, and by designing the interoptode distance according to the depth of the target region, this vertically stacked optoelectronic sensor is ...
Taeyeon Lee +9 more
wiley +1 more source
Hypoxia-inducible factor-1 mediates the biological effects of oxygen on human trophoblast differentiation through TGFβ3 [PDF]
, 2000 Isabella Caniggia +6 more
openalex +1 more source
Advanced Healthcare Materials, EarlyView.A kirigami‐inspired breathable smart contact lens is reported for wireless monitoring of corneal hypoxia and microenvironment. The ultrathin (55 µm) and flexible sensing device enables digitalized, in situ and precise monitoring of dissolved oxygen, humidity, and temperature (R2 >0.98).
Jiaxue Zhu +11 more
wiley +1 more source
Guoji laonian yixue zazhiDiabetes mellitus(DM) stands as a multifaceted metabolic disorder marked by heightened blood glucose levels and an elusive pathogenesis.Hypoxia-inducible factor-1(HIF-1) emerges as a pivotal transcription factor triggered within hypoxic environments.Its ...
Jing Cai +4 more
doaj +1 more source
Advanced Healthcare Materials, Volume 14, Issue 7, March 14, 2025.BX‐001N, a polyethylene glycol‐conjugated bilirubin 3α nanoparticle, is the first GMP‐grade, synthetic bilirubin‐based nanomedicine. It effectively attenuates acute renal injury, facilitates subacute renal recovery, and suppresses chronic fibrosis after renal ischemia/reperfusion injury via anti‐oxidant and immune‐modulating activity.
Ji‐Jing Yan +13 more
wiley +1 more source
Hypoxia-Inducible Factor 1-Related Diseases and Prospective Therapeutic Tools
Journal of Pharmacological Sciences, 2004 Hypoxia-inducible factor 1 (HIF-1) is a transcription factor that functions as a master regulator of oxygen homeostasis. HIF-1 regulates the expressions of the proteins that increase oxygen delivery, which enables cells to survive in oxygen-deficient ...
Jong-Wan Park +2 more
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