Results 131 to 140 of about 229,207 (357)
Hypoxia Inducible Factor 1 (HIF-1) DNA-Binding Activity is Present in Retinal Pigment Cells. A Possible Role for HIF-1 in the Retinopathy of Prematurity.• 1062 [PDF]
, 1998 Ashima Madan +2 more
openalex +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Background and Purpose White matter hyperintensities (WMH) are a core neuroimaging marker of cerebral small vessel disease (CSVD). Sleep apnoea (SA) is a recognized vascular risk factor, but its associations with regional WMH burden, short‐interval WMH change and cognitive performance in population‐based cohorts remain incompletely defined. We
Peng Cheng +4 more
wiley +1 more source
Structural and functional analysis of hypoxia-inducible factor 1
Kidney International, 1997 Hypoxia-inducible factor 1 (HIF-1) is a basic helix-loop-helix protein that activates transcription of hypoxia-inducible genes, including those encoding: erythropoietin, vascular endothelial growth factor, heme oxygenase-1, inducible nitric oxide synthase, and the glycolytic enzymes aldolase A, enolase 1, lactate dehydrogenase A, phosphofructokinase I,
Semenza, Gregg L. +9 more
openaire +2 more sources
Advanced Functional Materials, EarlyView.Bio‐based and (semi‐)synthetic zwitterion‐modified novel materials and fully synthetic next‐generation alternatives show the importance of material design for different biomedical applications. The zwitterionic character affects the physiochemical behavior of the material and deepens the understanding of chemical interaction mechanisms within the ...
Theresa M. Lutz +3 more
wiley +1 more source
Ets-1 participates in and facilitates developmental expression of hypoxia-induced mitogenic factor in mouse lung [PDF]
, 2006 Bo Li
openalex +1 more source
Advanced Functional Materials, EarlyView.A swelling‐programmed micropatterned hydrogel guides adherent cells through a controlled transition from cell–matrix anchoring to cadherin‐mediated cell–cell compaction, enabling rapid assembly of high‐viability spheroids with defined size and morphology.
Han Gyeol Nam +8 more
wiley +1 more source
Hypoxia-inducible factor 1 protects neurons from Sarm1-mediated neurodegeneration
Cell ReportsSummary: The sterile alpha and TIR motif-containing 1 (Sarm1) NAD+ hydrolase drives neurodegeneration, but how Sarm1 activity is regulated remains poorly defined.
Paul Meraner +5 more
doaj +1 more source
Advanced Functional Materials, EarlyView.We present a tissue‐stimulator platform for seamless electrode integration with pancreatic tissue, applying uniform electrical stimulation through optimized design with biohybrid 3D printing. Advantageous effects of electrical stimulation on β‐cell function were observed, including enhanced calcium signaling, islet morphology, and maturation.
Jihwan Kim +7 more
wiley +1 more source
Hypoxia‐inducible factor‐1 improves inotropic responses of cardiac myocytes in ageing heart without affecting mitochondrial activity [PDF]
, 2010 Tao Tan +3 more
openalex +1 more source
Ultrasmall Platinum Nanoparticles for Radiation‐Enhanced Cancer Therapy
Advanced Functional Materials, EarlyView.This work proposes a nanomedicine‐based strategy to enhance X‐ray radiotherapy for cancer treatment. Ultrasmall Pt‐NPs exhibit catalase‐like activity that may contribute to modulation of the tumor microenvironment and amplify interactions between radiation and biological matter, leading to increased DNA damage.
Miguel Encinas‐Gimenez +8 more
wiley +1 more source