Results 271 to 280 of about 649,237 (386)

Targeting Hypoxia‐Inducible Factor‐1&agr;/Pyruvate Dehydrogenase Kinase 1 Axis by Dichloroacetate Suppresses Bleomycin‐induced Pulmonary Fibrosis

American Journal of Respiratory Cell and Molecular Biology, 2017
Justin Goodwin, Hyunsung Choi, Meng-Hsiung Hsieh, Michael L. Neugent, Jung-Mo Ahn, Heather N. Hayenga, P. Singh, D. Shackelford, In-kyu Lee, V. Shulaev, S. Dhar, Norihiko Takeda, Jung-whan Kim   +12 more
semanticscholar   +1 more source

The Role of Hypoxia-Inducible Factor 1 Alpha in Acute-on-Chronic Liver Failure. [PDF]

Int J Mol Sci
Mücke MM, El Bali N, Schwarzkopf KM, Uschner FE, Kraus N, Eberle L, Mücke VT, Bein J, Beyer S, Wild PJ, Schierwagen R, Klein S, Zeuzem S, Welsch C, Trebicka J, Brieger A.   +15 more
europepmc   +1 more source

Unraveling Neurodevelopment: Synergistic Effects of Intrinsic Genetic Programs and Extrinsic Environmental Cues

Advanced Science, EarlyView.
Overview of the regulation of intrinsic and extrinsic signals during neurodevelopment. Intrinsic genetic signals from NSCs, in conjunction with cues from microglia and blood vessels, collaboratively regulate the proliferation of NSCs, their fate determination, synaptogenesis, synaptic pruning, neuronal survival, and death, as well as communication ...
Yanyan Wang, Shukui Zhang, Huiyang Jia, Fen Ji, Jianwei Jiao   +4 more
wiley   +1 more source

c-Myc Sensitization to Oxygen Deprivation-induced Cell Death Is Dependent on Bax/Bak, but Is Independent of p53 and Hypoxia-inducible Factor-1 [PDF]

, 2004
Joslyn K. Brunelle, Matthew T. Santore, G. R. Scott Budinger, Yueming Tang, Terrence A. Barrett, Wei‐Xing Zong, Eugene Kandel, Brian Keith, M. Celeste Simon, Craig B. Thompson, Nissim Hay, Navdeep S. Chandel   +11 more
openalex   +1 more source

Hypoxia-Inducible Factor 1-Alpha

Definitions, 2020

semanticscholar   +1 more source

Hypoxia-inducible factor 1-alpha and lactate dehydrogenase-A axis in metabolic changes and aggression in esophageal squamous-cell carcinoma.

World J Gastrointest Oncol
Chen X, Liu HY, Zhou WB, Zhang LL, Huang J, Bao DW.   +5 more
europepmc   +1 more source

Hypoxia inducible factor 1-alpha in the pathogenesis of abdominal aortic aneurysms in vivo: A narrative review. [PDF]

JVS Vasc Sci
Bruhn PJ, Jessen ML, Eiberg J, Ghulam Q.
europepmc   +1 more source

Metal–Organic Frameworks: Unlocking New Frontiers in Cardiovascular Diagnosis and Therapy

Advanced Science, EarlyView.
Metal–organic frameworks (MOFs), are composed of metal ions and bridging organic ligands, are recognized as an excellent platform for host‐gust chemistry. Its rich structural composition, modifiable sites, and multilevel pore distribution can provide delivery and release of signaling molecules, probes, and therapeutic drugs, which exhibit great medical
Qilu Wu, Yuxiao Feng, Mathilde Lepoitevin, Meng Yu, Christian Serre, Jun Ge, Yuan Huang   +6 more
wiley   +1 more source

Small Molecule-Mediated Anti-Cancer Therapy via Hypoxia Inducible Factor-1 Blockade [PDF]

, 2004
Gordon R. Macpherson, William D. Figg
openalex   +1 more source

Cannabidiol effectively prevents oxidative stress and stabilizes hypoxia-inducible factor-1 alpha (HIF-1α) in an animal model of global hypoxia. [PDF]

Sci Rep
Kletkiewicz H, Wojciechowski MS, Rogalska J.   +2 more
europepmc   +1 more source