Results 271 to 280 of about 1,301,346 (361)

Rational Design of Inner Ear Drug Delivery Systems

Advanced Science, EarlyView.
Hearing loss is a common disease affecting many people, and inner ear lesions are one of the most important causes. This review focuses on the treatment of inner ear hearing loss by drug delivery systems. It includes the current methods and technologies developed, and it predicts possible directions.
Xiayidan Maimaitikelimu, Zhiyan Xuan, Haoyu Ren, Keng Chen, Hui Zhang, Huan Wang   +5 more
wiley   +1 more source

Therapeutic Targeting of Hypoxia-Inducible Factors in Cancer. [PDF]

Int J Mol Sci
Musleh Ud Din S, Streit SG, Huynh BT, Hana C, Abraham AN, Hussein A.   +5 more
europepmc   +1 more source

Hypoxia-Inducible Factors and Burn-Associated Acute Kidney Injury-A New Paradigm? [PDF]

Int J Mol Sci, 2022
Enescu DM, Parasca SV, Badoiu SC, Miricescu D, Ripszky Totan A, Stanescu-Spinu II, Greabu M, Jinga V.   +7 more
europepmc   +1 more source

Characterization of a Hypoxia-inducible Factor (HIF-1α) from Rainbow Trout [PDF]

, 2001
Arto Soitamo, Christina M.I. Råbergh, Max Gassmann, Lea Sistonen, Mikko Nikinmaa   +4 more
openalex   +1 more source

Hypoxia-inducible factors regulate tumorigenic capacity of glioma stem cells.

Cancer Cell, 2009
Zhizhong Li, S. Bao, Qiulian Wu, Hui Wang, C. Eyler, S. Sathornsumetee, Q. Shi, Yiting Cao, J. Lathia, R. McLendon, A. Hjelmeland, J. Rich   +11 more
semanticscholar   +1 more source

Acod1 Promotes PAD4 Ubiquitination via UBR5 Alkylation to Modulate NETosis and Exert Protective Effects in Sepsis

Advanced Science, EarlyView.
In this study, Acod1 knockout in CLP mice significantly increases peripheral blood NET levels, exacerbating inflammation, organ damage, and reducing survival. Further research shows that UBR5 interacts with PAD4, a key NET formation protein. Acod1/itaconate (ITA) enhances the enzymatic activity of UBR5 by alkylating the Cys2768 site, promoting the K48 ...
Huifan Liu, Guoqing Jing, Shujuan Wu, Min Yuan, Yingyue Dong, Xue Chen, Huimin Zhou, Hailong Gong, Jing Zuo, Xiaojing Wu, Xuemin Song   +10 more
wiley   +1 more source

Understanding the Significance of Hypoxia-Inducible Factors (HIFs) in Glioblastoma: A Systematic Review. [PDF]

Cancers (Basel)
Begagić E, Bečulić H, Džidić-Krivić A, Kadić Vukas S, Hadžić S, Mekić-Abazović A, Šegalo S, Papić E, Muchai Echengi E, Pugonja R, Kasapović T, Kavgić D, Nuhović A, Juković-Bihorac F, Đuričić S, Pojskić M.   +15 more
europepmc   +1 more source

Hypoxia-inducible factors, mTOR, and astrin constitute an integrative regulatory network in colon cancer cells. [PDF]

Biochem Biophys Rep, 2022
Saint-Martin A, Morquecho-León MA, Castañeda-Patlán MC, Robles-Flores M.   +3 more
europepmc   +1 more source

Hypoxia-Induced Transcriptional Activation of Vascular Endothelial Growth Factor Is Inhibited by Serum

, 2000
Gisela D’Angelo, Annie Ladoux, Christian Frelin   +2 more
openalex   +2 more sources

Hepatocyte growth factor signalling stimulates hypoxia inducible factor-1 (HIF-1) activity in HepG2 hepatoma cells [PDF]

, 2001
Lorenza Tacchini
openalex   +1 more source