Results 161 to 170 of about 44,731 (245)

Kaempferol Attenuates Myocardial Ischemia–Reperfusion Injury by Suppressing Ferroptosis via the KEAP1–Nrf2–GPX4 Axis

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Myocardial ischemia/reperfusion (I/R) injury is characterized by cardiomyocyte death, excessive oxidative stress, inflammation, and ferroptosis, which collectively limit the efficacy of reperfusion therapy. In this study, we investigated whether kaempferol (KAE), a natural flavonol with antioxidative and antiinflammatory properties, could ...
Yan‐Bo Zhao, Ling‐Ling Sun, Xiao‐Hua Shen, Min Wang, Mei‐Hui Wang, Lu‐Lu Liu, Kai Zhang   +6 more
wiley   +1 more source

Mitochondrial Dynamic Proteins MiD49 and MiD51 as Novel Targets of Cardioprotection. [PDF]

Cells
Samangouei P, Crespo-Avilan GE, Hall AR, Hernandez-Resendiz S, Elder JM, Osellame LD, Tee NGZ, Katwadi K, Ong SB, Kwek XY, Beikoghli Kalkhoran S, Burke N, Yellon DM, Hausenloy DJ.   +13 more
europepmc   +1 more source

Endoscopic Suture Ligation and Sclerotherapy for Pharyngolaryngeal Venous Malformation

The Laryngoscope, EarlyView.
This study evaluated suture ligation combined with sclerotherapy in 53 patients with pharyngolaryngeal venous malformations. A single procedure achieved complete resolution in 79.25% of cases, with no serious complications or need for prophylactic tracheostomy.
Jiajun Tian, Juke Ma, Ahmad A. Hariri, Zhenghua Lv, Peng Cui, Wei Xu   +5 more
wiley   +1 more source

HIF1A transcriptionally activates CDKN1A to drive ferroptosis in skeletal muscle ischaemia-reperfusion injury. [PDF]

J Orthop Translat
Zhou M, Wang K, Jin Y, Liu J, Xue Y, Wang Y, Jia X, Liu H, Wang P, Li Z, Pan X, Ma Y, Rui Y.   +12 more
europepmc   +1 more source

Proteomics of Nitrotyrosine: Integrating Mass Spectrometry and Immunodetection in Redox‐Driven Pathology

Mass Spectrometry Reviews, EarlyView.
ABSTRACT Nitrooxidative stress, driven by excess reactive nitrogen species like peroxynitrite, contributes to the pathogenesis of many chronic diseases. Among its molecular footprints, 3‐nitrotyrosine (3NT) has emerged as a biologically relevant marker of protein nitration.
Brîndușa Alina Petre
wiley   +1 more source

Cardioprotective effects of prolyl hydroxylase inhibitors during reperfusion in myocardial infarction: A study using cardiosphere-derived cells. [PDF]

Exp Physiol
Salhöfer L, Hendgen-Cotta UB, Fandrey J, Schreiber T, Leu T.   +4 more
europepmc   +1 more source

Cardiac surgery-associated acute kidney injury. [PDF]

BJA Educ
Oosterom-Eijmael MJP, Hermanns H, Lankadeva YR, Hulst AH.   +3 more
europepmc   +1 more source

CLEC14A correlates with neutrophil infiltration in hepatocellular carcinoma and mediates neutrophil recruitment across liver endothelial cells

The Journal of Pathology, EarlyView.
Abstract Hepatocellular carcinoma (HCC) is a leading cause of cancer‐related deaths globally, and cases are predicted to rise dramatically over the next few years. Overcoming the immune microenvironment in HCC remains a challenge, and innate immune populations such as tumour‐associated neutrophils can potentially impair the success of immunotherapy ...
Joanne M O'Rourke, Dean Kavanagh, Ayla O'Keeffe, Kylie Savoye, Kaiyi Yang, Daniel A Patten, Catherine E Willoughby, Josep M Llovet, Georgiana Neag, Helen L Reeves, Peter W Hewett, Neena Kalia, Tahir Shah, Yuk Ting Ma, Kelly Hunter, Joe Flint, Jack L McMurray, Owen Cain, Fabian Spill, Derek A Mann, Amy J Naylor, Victoria Heath, Christopher J Weston, Roy Bicknell, Shishir Shetty   +24 more
wiley   +1 more source

Investigating the roles of macrophage age and circulating extracellular vesicles in cytoprotection of hypoxic renal tubular cell stress. [PDF]

BMC Mol Cell Biol
Livkisa D, Lundy DJ, Lee TL, Szomolay B, Liao CT.   +4 more
europepmc   +1 more source

Fetal Brain Abnormalities Following Laser Surgery for Twin‐to‐Twin Transfusion Syndrome: Imaging Patterns and Evolution

Prenatal Diagnosis, EarlyView.
ABSTRACT Introduction Severe brain injury has been reported following fetoscopic laser ablation (FLA) for twin‐to‐twin transfusion syndrome (TTTS), but imaging patterns and temporal evolution remain poorly defined. This study aimed to characterize the progression of severe brain injury after FLA. Methods We conducted a retrospective case series of TTTS
Yada Kunpalin, Elka Miller, Ingrid Larsen, Kamini Raghuram, Catherine Windrim, Nimrah Abbasi, Greg Ryan, Tim Van Mieghem, Shiri Shinar   +8 more
wiley   +1 more source