Results 151 to 160 of about 927,905 (356)

Photoactivated Proximity Protein Labeling Reveals Enhanced Tumor Retention of a D‐Peptide‐Ruthenium Prodrug Conjugate

Advanced Healthcare Materials, EarlyView.
Six stereoisomeric ruthenium‐peptide conjugates were synthesized and characterized, which showed high potential in photoactivated chemotherapy (PACT) and proximity protein labeling. Abstract Amino acid chirality is known to influence the biological properties of peptide‐containing prodrugs.
Liyan Zhang, Peiyuan Wang, Hildert Bronkhorst, Yurii Husiev, Ludovic Bretin, Maarten N. van Ginkel, Wen Sun, Sylvestre Bonnet   +7 more
wiley   +1 more source

Hemodynamic Changes in Fetal Lamb in Utero in Response to Asphyxia, Hypoxia, and Hypercapnia [PDF]

, 1962
N.S. Assali, L. W. Holm, Nalini Sehgal
openalex   +1 more source

Microscopically Adaptable Bioink Guide Cell Compartmentalization toward Morphogenesis of a Functional Vasculature‐Like System

Advanced Healthcare Materials, EarlyView.
Contractile vasculatures are fabricated through a one‐step bioprinting strategy. The adaptable microenvironment provided by ECM‐mimicking bioink triggers cell sorting and compartmentalization of endothelial cells and vascular smooth muscle cells toward a histological configuration by focal adhesion kinase‐mediated upregulation of cell adhesion and ...
Jun Chen, Yuqiong Wu, Jiarong Huang, Junjin Jie, Chan Huang, Di Zhang, Yuxin Huang, Rui Mao, Ming Zhao, Lin‐Ping Wu   +9 more
wiley   +1 more source

Conditions governing the pulmonary vascular response to ventilation hypoxia and hypoxaemia in the dog [PDF]

, 1968
I. de Burgh Daly, C. C. Michel, D. J. Ramsay, B. A. Waaler   +3 more
openalex   +1 more source

Engineering Volumetric Tissue Analogs via Assembly of Endothelial Cell‐Covered Spheroidal Microtissues

Advanced Healthcare Materials, EarlyView.
An engineering strategy to fabricate highly vascularized volumetric tissues with capillary networks is developed. Endothelial cell‐covered spheroidal microtissues with high structural integrity are efficiently produced using bioprinting technology. These spheroidal microtissues are then assembled and cultured under perfusion conditions, resulting in ...
Hyeongkwon Oh, Jae‐Hun Kim, Sunwoo Lee, Jin‐Hyung Shim, Won‐Soo Yun, Songwan Jin   +5 more
wiley   +1 more source

Dynamic Characteristics of the Cardiovascular Autonomic Effects during Severe Arterial Hypoxia in the Unanesthetized Rabbit [PDF]

, 1969
Paul Körner, John B. Uther
openalex   +1 more source

A Modular Perfusion Bioreactor Platform for Simulating Bone Regeneration and Fracture Healing: Integrating Mechanical Loading and Dual Perfusion for Advanced In Vitro Models

Advanced Healthcare Materials, EarlyView.
A modular bioreactor platform was developed in order to replicate bone homeostasis and pathology, thereby integrating mechanical loading, dynamic perfusion, and a 3D‐printed microfluidic chamber. With precise control of environmental parameters and dual perfusion for composite tissue models, the system enhances physiological relevance for studying bone
Moritz Pfeiffenberger, Alexandra Damerau, Johannes Plank, Adel Ahmed, Mario Thiele, Jan Saam, Paula Hoff, Timo Gaber, Frank Buttgereit   +8 more
wiley   +1 more source

Salidroside suppresses gastric cancer progression via miR-1343-3p-mediated repression of ACOT11 and disruption of fatty acid metabolism

Frontiers in Oncology
ObjectiveSalidroside, a bioactive compound derived from Rhodiola, has been demonstrated to upregulate the tumor suppressor miR-1343-3p, leading to suppression of gastric cancer growth.
Zhendong Zhang, Zhendong Zhang, Mingyuan Cao, Mingyuan Cao, Yuxin Du, Yuxin Du, Pingyi Wang, Pingyi Wang, Xinrui Hou, Xinrui Hou, Xiaoping Wang, Xiaoping Wang   +11 more
doaj   +1 more source

Differences in Cardiac Hypertrophy in Exercise and in Hypoxia [PDF]

, 1965
Edward J. Van Liere, BARBARA BAUGH KRAMES, D. Northup   +2 more
openalex   +1 more source

Preventing hypoxia [PDF]

European Journal of Anaesthesiology, 2016
Zilberman, Paul Norbert, Biro, Peter
openaire   +2 more sources