Results 151 to 160 of about 1,131,072 (401)

Ro 31‐8220 suppresses bladder cancer progression via enhancing autophagy in vitro and in vivo

FEBS Open Bio, EarlyView.
The pan‐protein kinase C inhibitor Ro‐31‐8220 demonstrates potent anti‐bladder cancer effects both in vitro and in vivo by suppressing migration/invasion, inducing apoptosis and crucially activating autophagy, where blocking autophagy with chloroquine reduces its cell‐killing efficacy, suggesting its promise as a novel therapeutic candidate requiring ...
Shengjun Fu, Yan Tao, Shan Wu, Yuwen Gong, Youli Zhao, Shaomin Niu, Hui Cheng, You Mu, Na Xu, Ying Wang, Jianzhong Lu, Shanhui Liu, Lanlan Li   +12 more
wiley   +1 more source

Asymmetric Dimethylarginine at Sea Level Is a Predictive Marker of Hypoxic Pulmonary Arterial Hypertension at High Altitude

Frontiers in Physiology, 2019
Background: Prolonged exposure to altitude-associated chronic hypoxia (CH) may cause high-altitude pulmonary hypertension (HAPH). Chronic intermittent hypobaric hypoxia (CIH) occurs in individuals who commute between sea level and high altitude.
Patricia Siques, Patricia Siques, Julio Brito, Julio Brito, Edzard Schwedhelm, Eduardo Pena, Eduardo Pena, Fabiola León-Velarde, Fabiola León-Velarde, Juan José De La Cruz, Rainer H. Böger, Rainer H. Böger, Juliane Hannemann, Juliane Hannemann   +13 more
doaj   +1 more source

STUDIES ON THE MECHANISM OF ERYTHROPOIETIC STIMULATION IN PARABIOTIC RATS DURING HYPOXIA [PDF]

, 1950
Kurt R. Reißmann
openalex   +1 more source

SARS‐CoV‐2 Is Linked to Brain Volume Loss in Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective The impact of SARS‐CoV‐2 infection on brain and spinal cord pathology in patients with multiple sclerosis (pwMS) remains unclear. We aimed to describe changes in brain lesion activity and brain and spinal cord volumes following SARS‐CoV‐2 infection.
Tomas Uher, Dominika Stastna, Ingrid Menkyova, Vaclav Capek, Jiri Lindner, Petra Nytrova, Jan Krasensky, Eliza Varju, Miguel D'haeseleer, Eva Kubala Havrdova, Dana Horakova, Manuela Vaneckova, Niels Bergsland   +12 more
wiley   +1 more source

Endurance Training in Normobaric Hypoxia Imposes Less Physical Stress for Geriatric Rehabilitation

Frontiers in Physiology, 2017
Rationale: Evidence suggests that training in hypoxia can be very effective even while requiring less physical effort. We therefore aimed to measure the effect of endurance training under hypoxic conditions on pulmonary and cardiovascular parameters in ...
Stephan Pramsohler, Martin Burtscher, Martin Faulhaber, Hannes Gatterer, Linda Rausch, Arn Eliasson, Nikolaus C. Netzer, Nikolaus C. Netzer, Nikolaus C. Netzer   +8 more
doaj   +1 more source

A depletable pool of adenosine in area CA1 of the rat hippocampus [PDF]

, 2001
Adenosine plays a major modulatory and neuroprotective role in the mammalian CNS. During cerebral metabolic stress, such as hypoxia or ischemia, the increase in extracellular adenosine inhibits excitatory synaptic transmission onto vulnerable neurons via
Caldwell, Darren, Dale, Nicholas, Frenguelli, Bruno G., Nuritova, Feruza, Pearson, Tim   +4 more
core   +1 more source

BLOOD FLOW THROUGH EACH LUNG IN MAN DURING UNILATERAL HYPOXIA 1 [PDF]

, 1955
A. P. Fishman, Aaron Himmelstein, H. W. Fritts, A. Cournand   +3 more
openalex   +1 more source

Discovery and Treatment of Action Potential‐Independent Myotonia in Hyperkalemic Periodic Paralysis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Hyperkalemic periodic paralysis (hyperKPP) is characterized by attacks of transient weakness. A subset of hyperKPP patients suffers from transient involuntary contraction of muscle (myotonia). The goal of this study was to determine mechanisms causing myotonia in hyperKPP.
Chris Dupont, Adam Deardorff, Murad Nawaz, Andrew A. Voss, Mark M. Rich   +4 more
wiley   +1 more source

The effect of hypoxia on the heart rate of the dog with special reference to the contribution of the carotid body chemoreceptors [PDF]

, 1959
M. de Burgh Daly, Mary J. Scott
openalex   +1 more source

Hypoxia

Current pediatrics, 2016
The discourse characterizes types, causes and key links of the pathogenesis of different types of hypoxia, their main manifestations and mechanisms of their development, disorders in the body under hypoxic conditions, principles of their elimination.
openaire   +3 more sources