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Mechanistic Study of Hypoxia-Mediated Regulation of Osteoblast Senescence via ATP6V1A-Dependent Modulation of Metabolic Remodeling. [PDF]
Xiao H +8 more
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Mitochondrial oxidative stress under hypoxia promotes gastric mucosal injury in portal hypertensive gastropathy. [PDF]
Luo J, Xie K, Ou X, Tan S.
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Morphofunctional Features of the Immune System Response to Sublethal Hypoxic Load in Hypoxia-Tolerant and Hypoxia-Susceptible Animals. [PDF]
Kirillova M +4 more
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Hypoxia. 5. Hypoxia and hematopoiesis
American Journal of Physiology-Cell Physiology, 2011Our understanding of organismal responses to hypoxia has stemmed from studies of erythropoietin regulation by hypoxia that led to the discovery of the master regulator of the hypoxic response, i.e., hypoxia-inducible factor (HIF). This is a transcription factor that is now known to induce the expression of a battery of genes in response to hypoxia ...
Donghoon, Yoon +2 more
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Science, 2019
In a remote Andean mining town, scientists are studying how life at extremely low oxygen levels ravages the body.
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In a remote Andean mining town, scientists are studying how life at extremely low oxygen levels ravages the body.
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Hypoxia-inducible factors, hypoxia, and tumor angiogenesis
Current Opinion in Hematology, 2006The transcription factor hypoxia-inducible factor is activated by low oxygen to promote the expression of target genes that allow cellular, tissue, and organismal adaptation to low oxygen. Hypoxia-inducible factor is activated not only by hypoxia but also as a consequence of genetic mutations in a variety of tumors.
Michaela, Gruber, M Celeste, Simon
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