Results 11 to 20 of about 198,205 (343)
Effects of Environmental and Pathological Hypoxia on Male Fertility [PDF]
Frontiers in Cell and Developmental Biology, 2021 Male infertility is a widespread health problem affecting approximately 6%–8% of the male population, and hypoxia may be a causative factor. In mammals, two types of hypoxia are known, including environmental and pathological hypoxia.
Zhibin Li +14 more
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Hypoxia diminishes the detoxification of the environmental mutagen benzo[a]pyrene [PDF]
Mutagenesis, 2014 Hypoxia promotes genetic instability and is therefore an important factor in carcinogenesis. We have previously shown that activation of the hypoxia responsive transcription factor HIFα can enhance the mutagenic phenotype induced by the environmental mutagen benzo[a]pyrene (BaP).
Marten A. Schults +5 more
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Biogeochemical and environmental drivers of coastal hypoxia
Journal of Marine Systems, 2014 AbstractRecent reports have demonstrated that hypoxia is widespread in the coastal zone of the Baltic Sea. Here we evaluate the long-term trends of dissolved oxygen in bottom waters and of the drivers of coastal hypoxia. Eleven of the 33 sites evaluated had increasing trends of bottom water dissolved oxygen, but only the Stockholm Archipelago presents ...
Ángela M. Caballero-Alfonso +2 more
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Deaths from Environmental Hypoxia and Raised Carbon Dioxide [PDF]
Academic Forensic Pathology, 2018 This paper reviews deaths in which there is an environment that is low in oxygen and/or has elevated levels of carbon dioxide. These deaths present problems to autopsy pathologists, as the autopsy is typically negative and postmortem toxicology cannot be used to detect the effects of hypoxia and raised levels of carbon dioxide. Deaths from hypoxia and
Christopher M. Milroy
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Lead Intoxication Under Environmental Hypoxia Impairs Oral Health [PDF]
Journal of Toxicology and Environmental Health, Part A, 2014 We have reported that chronic lead intoxication under hypoxic environment induces alveolar bone loss that can lead to periodontal damage with the subsequent loss of teeth. The aim of the present study was to assess the modification of oral inflammatory parameters involved in the pathogenesis of periodontitis in the same experimental model.
Antonela Romina Terrizzi +4 more
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The Influence of Environmental Hypoxia on Hemostasis—A Systematic Review [PDF]
Frontiers in Cardiovascular Medicine, 2022 Humans have been ascending to high altitudes for centuries, with a growing number of professional- and leisure-related sojourns occurring in this millennium. A multitude of scientific reports on hemostatic disorders at high altitude suggest that hypoxia is an independent risk factor.
Benedikt Treml +4 more
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Skin Hypoxia: A Promoting Environmental Factor in Melanomagenesis [PDF]
Cell Cycle, 2006 Melanomagenesis is a complex phenomenon in which environmental, genetic and host factors play a role. Sun burns in early childhood are a known risk factor in melanoma development. Alteration of prosurvival genes such as Ras and Akt and loss of function of the p16(INK4a)-CDK4/6-pRb and p14(ARF)-HDM2-p53 pathways are strongly associated with human ...
Barbara Bedogni, Marianne Broome Powell
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Caudwell Xtreme Everest: A prospective study of the effects of environmental hypoxia on cognitive functioning [PDF]
PLOS ONE, 2017 BACKGROUND: The neuropsychological consequences of exposure to environmental hypobaric hypoxia (EHH) remain unclear. We thus investigated them in a large group of healthy volunteers who trekked to Mount Everest base camp (5,300 m). METHODS: A neuropsychological (NP) test battery assessing memory, language, attention, and executive function was ...
Konstadina Griva +16 more
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Regulation of myogenesis by environmental hypoxia [PDF]
Journal of Cell Science, 2016 ABSTRACT In aerobic organisms, oxygen is a critical factor for tissue and organ morphogenesis from embryonic development throughout the adult life. It regulates various intracellular pathways involved in cellular metabolism, proliferation, cell survival and fate.
Magdalena Hidalgo +6 more
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Vasopressin and oxytocin release during prolonged environmental hypoxia in the rat [PDF]
Thorax, 1997 The mechanism causing peripheral oedema in hypoxaemic chronic obstructive pulmonary disease has not been established. Vasopressin, a powerful antidiuretic hormone involved in salt and water homeostasis, is released in response to acute hypoxia. However, the effect of prolonged hypoxaemia on hypothalamic and pituitary release of the magnocellular ...
Haluk Keleştimur +3 more
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