Results 201 to 210 of about 97,129 (264)

A Hydrodynamic Bioreactor for High‐Yield Production of Extracellular Vesicles from Stem Cell Spheroids with Defined Cargo Profiling

Advanced Science, EarlyView.
This study harnesses hydrodynamic flows to generate, confine and stimulate stem cell spheroids, enabling the large‐scale production of extracellular vesicles (EVs). This innovative method not only streamlines spheroid formation and subsequent EV release in a single, integrated process, but also ensures the generation of EVs with enhanced biological ...
Solène Lenoir, Elliot Thouvenot, Giacomo Gropplero, Léonie Dec, Damarys Loew, Clotilde Théry, Jose E Perez, Claire Wilhelm   +7 more
wiley   +1 more source

Euryhaline Atlantic stingray (<i>Hypanus sabinus</i>) exhibit elevated oxygen supply capacity in hyposaline water: implications for estuarine species resilience and conservation. [PDF]

Conserv Physiol
Emmons SM, Rummer JL, Kilborn JP, Pierce MA, Timpe AW, Simpfendorfer CA, Seibel BA.   +6 more
europepmc   +1 more source

Single‐Cell Insights Into Macrophage Subtypes in Pulmonary Infections

Advanced Science, EarlyView.
This review highlights the dynamic plasticity of macrophages during pulmonary infections and proposes an integrative framework defining six functional subtypes: Inflam‐Ms, Hub‐Ms, Reg‐Ms, Prolif‐Ms, Memory‐Ms, and Senesc‐Ms. Single‐cell omics delineate their distinct roles in homeostasis and infection, refining our understanding of macrophage ...
Zhaoheng Lin, Yuxiao Zheng, Yu Zhong, Hongyan Wang   +3 more
wiley   +1 more source

From basin to gulf: Conservation tillage improves soil health but exacerbates hypoxia. [PDF]

NPJ Sustain Agric
Liang K, Zhang X, McCarty GW, Zhao K, Gao F.   +4 more
europepmc   +1 more source

Looking for Resistance to Soft Rot Disease of Potatoes Facing Environmental Hypoxia [PDF]

Tomasz Maciąg, Edmund Kozieł, Katarzyna Otulak-Kozieł, Sylwia Jafra, Robert Czajkowski   +4 more
openalex   +1 more source

NQO1/p65/CXCL12 Axis‐Recruited Tregs Mediate Resistance to Anti‐PD‐1 Plus Lenvatinib Therapy in PIVKA‐II‐Positive Hepatocellular Carcinoma

Advanced Science, EarlyView.
High PIVKA‐II expression in HCC correlates with resistance to anti‐PD‐1 plus lenvatinib, driven by an immunosuppressive TME. NQO1/p65/CXCL12 axis recruits Tregs to promote resistance to anti‐PD‐1 plus lenvatinib in HCC with high PIVKA‐II expression.
Biao Gao, Yafei Wang, Zhuoya Sun, Haowen Tang, Yinbiao Cao, Hao Jiang, Wenwen Zhang, Yinzhe Xu, Bingyang Hu, Zhe Liu, Guankun Mao, Xuerui Li, Junfeng Li, Tao Wan, Bing Liu, Xiao Zhao, Shunchang Jiao, Chonghui Li, Shichun Lu   +18 more
wiley   +1 more source

Forecasting coastal hypoxia using a blend of mechanistic and artificial intelligence models. [PDF]

Sci Rep
Ou Y, Xue ZG, Mukhopadhyay S, Rajasekaran M, Wichman D.   +4 more
europepmc   +1 more source

A Comparison of Physiological Responses in Yellowtail to Fatal Environmental Hypoxia and Exposure to <i>Chattonella marina</i>

, 1997
Atsushi Ishimatsu, Hajime Maruta, Tatsuya Oda, M. Ozaki   +3 more
openalex   +2 more sources

Transcriptomics Guided Engineering of Exosome‐Encapsulated Bifunctional Nanosheets Targeting the Immune‐PI3K/Akt Axis for Osteoporosis Therapy

Advanced Science, EarlyView.
A multifunctional nanosheet–exosome hybrid system incorporating f‐CA(OH) nanosheets enriched with abundant surface vacancies are developed. These nanosheets fuse with natural exosomes, endowing them with nanozyme‐like catalytic capabilities while retaining their inherent biological functions.
Rongze Tang, Guanhong Liu, Congcong Wang, Minghao Chao, Guangyu Ma, Pengjin Wei, Siling Du, Junjie Li, Yufan Liu, Chaonan Jing, Guoquan Wu, Ming Guan, Hongliang Chen, Fenglei Gao   +13 more
wiley   +1 more source

The gut microbiota in high-altitude medicine: intersection of hypoxic adaptation and disease management. [PDF]

Front Microbiol
Chen Q, Huang D, Liu J, Jia N, Shen Z, Pei C, Chen C, Liu Y, Wang Y, Shi S, Yi R, He Y, Wang F, Wang Z.   +13 more
europepmc   +1 more source