Results 231 to 240 of about 97,129 (264)

Carbon Monoxide Nanomodulator Reverses Ischemia‐Reperfusion Injury in Stroke: A Novel Dual‐Channel Therapy Mode of Co‐driving Neuroprotection and Neurogenesis

Advanced Science, EarlyView.
This work develops a biomimetic and reactive oxygen species‐activated carbon monoxide (CO) nanogenerator to penetrate blood‐brain barrier, arrive in stroke‐affected regions, and release CO in a controlled manner for an innovative dual‐channel therapy strategy via co‐driving neuroprotection and neurogenesis.
Xuegang Niu, Bin Gao, Hongyi Huang, Zesheng Li, Yibin Zhang, Quanlei Liu, Chao Zhang, Yang Dai, Jinkun Xu, Mingshan Liu, Yuanyuan Zhang, Yihe Wang, Penghu Wei, Yuanxiang Lin, Yongzhi Shan, Yumin Luo, Dezhi Kang, Guoguang Zhao   +17 more
wiley   +1 more source

Effects of fractional inspired O₂ on the O₂ pathway during submaximal and maximal exercise in male endurance athletes. [PDF]

Physiol Rep
Lehtonen E, Gagnon DD, Rissanen AE, Mikkola T, Peltonen JE.   +4 more
europepmc   +1 more source

Engineering Osteoimmune Responses with Functionalized Orthopedic Implants for Post‐Operative Osteosarcoma Treatment

Advanced Science, EarlyView.
Osteosarcoma is the most common primary bone tumor with limited treatment options and a terrible prognosis. This review provides a comprehensive summary of the recent development of osteoimmunomodulatory implants for post‐operative osteosarcoma treatment, of which the potential utility in evoking durable anti‐osteosarcoma immunity and accelerating bone
Yilong Dong, Lingshuang Wang, Hui Zhang, Menghuan Li, Zhong Luo, Yan Hu, Chunyuan Cai   +6 more
wiley   +1 more source

Metabolic alterations in erythrocytes associated with long-term hypoxia at high altitude. [PDF]

BMC Genomics
Yu T, Tan C, Zhou C, Hu L, Wang X, Ran Q, Xiao Y, Xiang L, Jiang Y, Li X, Xue P, Chen M, Chen L, Li Z.   +13 more
europepmc   +1 more source

Pulmonary‐Targeted Nanoparticles Interrupt the Malignant Mechanical and Biochemical Signaling Crosstalk for Idiopathic Pulmonary Fibrosis Therapy

Advanced Science, EarlyView.
Idiopathic pulmonary fibrosis (IPF) progression is driven by TGF‐β induced biochemical signals and mechanical signals from increased ECM stiffness. Pulmonary‐targeted VB‐RT NPs not only eliminate excessive ROS and penetrate the dense ECM collagen barrier via NO release, but also simultaneously interrupt the persistent malignant between mechanical and ...
Xue‐Na Li, Ya‐Ping Lin, Xi‐Xi Ma, Yue‐Fei Fang, Hui Wang, Chun‐Hui Cui, Chen Zhang, Jin‐You Piao, Jee‐Heon Jeong, Xian Wu Cheng, Lei Xing, Hu‐Lin Jiang   +11 more
wiley   +1 more source

Effect of 2-h hypoxic exposure on resting hepcidin levels in young adults. [PDF]

Physiol Rep
Lin CA, Naruse M, Tomiishi C, Matsudo H, Badenhorst CE, Goto K.   +5 more
europepmc   +1 more source

Effects of the interaction of environmental factors (hypoxia and ammonia) on fish

, 2013
Timothy M. Parker
openalex   +1 more source

Genetic and environmental influences in autism: guiding the future of tailored early detection and intervention. [PDF]

J Clin Invest
Bey AL, Soderling S, Dawson G.
europepmc   +1 more source

Whole methylomes reveal high-altitude-associated methylation at hypoxia and pigmentation genes in South American Indigenous populations. [PDF]

Environ Epigenet
Pryor Y, Rambaldi Migliore N, Alava DR, Di Gerlando R, Tineo DHT, Gusmão L, González-Andrade F, Achilli A, Lindo J.   +8 more
europepmc   +1 more source

Coastal Hypoxia in the Indian Ocean: Unraveling Drivers of Spatio-Temporal Variability. [PDF]

Glob Chang Biol
Yang F, Resplandy L, Zhao Y, Ditkovsky S.   +3 more
europepmc   +1 more source