Results 31 to 40 of about 4,147,965 (342)

The hypoxic transcription factor KlMga2 mediates the response to oxidative stress and influences longevity in the yeast Kluyveromyces lactis [PDF]

open access: yes, 2019
Hypoxia is defined as the decline of oxygen availability, depending on environmental supply and cellular consumption rate. The decrease in O2 results in reduction of available energy in facultative aerobes.
Bianchi, Michele M   +7 more
core   +1 more source

Distinct Mechanisms Underlie Developmental Plasticity and Adult Acclimation of Thermogenic Capacity in High-Altitude Deer Mice

open access: yesFrontiers in Physiology, 2021
Developmental plasticity can elicit phenotypic adjustments that help organisms cope with environmental change, but the relationship between developmental plasticity and plasticity in adult life (e.g., acclimation) remains unresolved. We sought to examine
Catherine M. Ivy   +3 more
doaj   +1 more source

The steroid hormone ecdysone regulates growth rate in response to oxygen availability

open access: yesScientific Reports, 2022
In almost all animals, physiologically low oxygen (hypoxia) during development slows growth and reduces adult body size. The developmental mechanisms that determine growth under hypoxic conditions are, however, poorly understood.
George P. Kapali   +4 more
doaj   +1 more source

Tumor Hypoxia Regulates Immune Escape/Invasion: Influence on Angiogenesis and Potential Impact of Hypoxic Biomarkers on Cancer Therapies

open access: yesFrontiers in Immunology, 2021
The environmental and metabolic pressures in the tumor microenvironment (TME) play a key role in molding tumor development by impacting the stromal and immune cell fractions, TME composition and activation.
R. Abou Khouzam   +7 more
semanticscholar   +1 more source

Molecular and biochemical responses of hypoxia exposure in Atlantic croaker collected from hypoxic regions in the northern Gulf of Mexico.

open access: yesPLoS ONE, 2017
A major impact of global climate change has been the marked increase worldwide in the incidence of coastal hypoxia (dissolved oxygen ...
Md Saydur Rahman, Peter Thomas
doaj   +1 more source

The Effect of Hypoxia and Hypoxia-Associated Pathways in the Regulation of Antitumor Response: Friends or Foes?

open access: yesFrontiers in Immunology, 2022
Hypoxia is an environmental stressor that is instigated by low oxygen availability. It fuels the progression of solid tumors by driving tumor plasticity, heterogeneity, stemness and genomic instability.
R. Abou Khouzam   +7 more
semanticscholar   +1 more source

An Inexpensive Open-Source Chamber for Controlled Hypoxia/Hyperoxia Exposure

open access: yesFrontiers in Physiology, 2022
Understanding hypoxia/hyperoxia exposure requires either a high-altitude research facility or a chamber in which gas concentrations are precisely and reproducibly controlled.
Tyler C. Hillman   +3 more
doaj   +1 more source

Hypoxia and Inflammation: Insights From High-Altitude Physiology

open access: yesFrontiers in Physiology, 2021
The key regulators of the transcriptional response to hypoxia and inflammation (hypoxia inducible factor, HIF, and nuclear factor-kappa B, NF-κB, respectively) are evolutionarily conserved and share significant crosstalk. Tissues often experience hypoxia
Kathy Pham   +2 more
doaj   +1 more source

Effects of hypoxia on benthic macrofauna and bioturbation in the Estuary and Gulf of St. Lawrence, Canada [PDF]

open access: yes, 2010
The bottom water in the 4300 m deep Lower St. Lawrence Estuary (LSLE) is persistently hypoxic in contrast to the normoxic bottom waters in the Gulf of St. Lawrence (GSL). We photographed the seabed at 11 stations in the Estuary and Gulf of St.
Archambault, Philippe   +4 more
core   +4 more sources

The Influence of Body Size and Hemoglobin Multiplicity on Critical Oxygen Threshold in Red Drum (Sciaenops ocellatus) [PDF]

open access: yes, 2016
Hypoxia is common in marine environments and fishes use a suite of cardiorespiratory adjustments to defend aerobic metabolism, including reducing standard metabolic rate (SMR), the minimum metabolic rate needed to sustain life at a specified temperature,
Pan, Yihang
core   +1 more source

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