Changes in Pulmonary Arterial Wall Mechanical Properties and Lumenal Architecture with Induced Vascular Remodeling [PDF]
, 2004 To explore and quantify pulmonary arterial remodeling we used various methods including micro-CT, high-resolution 3-dimensional x-ray imaging, to examine the structure and function of intact pulmonary vessels in isolated rat lungs.
Dawson, Christopher A +3 more
core +1 more source
Involvement of E3 Ligases and Deubiquitinases in the Control of HIF-α Subunit Abundance
Cells, 2019 The ubiquitin and hypoxia-inducible factor (HIF) pathways are cellular processes involved in the regulation of a variety of cellular functions. Enzymes called ubiquitin E3 ligases perform protein ubiquitylation.
Kateryna Kubaichuk, Thomas Kietzmann
doaj +1 more source
Ventilatory Phenotypes among Four Strains of Adult Rats. [PDF]
, 2002 Our purpose in this study was to identify different ventilatory phenotypes among four different strains of rats. We examined 114 rats from three in-house, inbred strains and one outbred strain: Brown Norway (BN;n = 26), Dahl salt-sensitive (n = 24), Fawn-
Dwinell, Melinda R. +4 more
core +2 more sources
Decades of Delay: EPA Leadership Still Lacking in Protecting America's Great River [PDF]
, 2016 This report demonstrates the continuing failure of EPA's voluntary approach and the continuing and growing threats of unregulated nitrogen and phosphorus pollution.
Alicia Lloyd +13 more
core
Establishing National Ocean Service Priorities for Estuarine, Coastal, and Ocean Modeling: Capabilities, Gaps, and Preliminary Prioritization Factors [PDF]
, 2007 This report was developed to help establish National Ocean Service priorities and chart new directions for research and development of models for estuarine, coastal and ocean ecosystems based on user-driven requirements and supportive of sound coastal ...
Cloyd, Emily T. +3 more
core
Effects of Hyperbaric Hypoxia on Some Enzyme Systems in the Mammalian Liver [PDF]
, 1978 The metabolic effects of hypobaric hypoxic stress on the mammalian liver were studied. The lactate dehydrogenase (LDH) and succinate dehydrogenase (SDH) activity of mouse liver homogenates were measured after exposure to an equivalent altitude of 36,000 ...
Baeyens, Dennis A., Meier, M. J.
core +2 more sources
Coping styles in farmed fish: consequences for aquaculture [PDF]
, 2017 Individual differences in physiological and behavioural responses to stressors are increasingly recognised as adaptive variation and thus raw material for evolution and fish farming improvements including selective breeding. Such individual variation has
Begout, Marie-Laure +9 more
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Acute environmental hypoxia activates autophagy in human skeletal muscle (1167.2)
The FASEB Journal, 2014 Hypoxia‐induced muscle wasting is a phenomenon often described at high altitude, which has been attributed to an altered protein metabolism. We hypothesized that acute normobaric hypoxia would favour a negative net protein balance by repressing anabolic and activating proteolytic signaling pathways at rest and post‐exercise. Twenty‐
Louise Deldicque +5 more
openaire +1 more source
Anthropogenic eutrophication and stratification strength control hypoxia in the Yangtze Estuary
Communications Earth & EnvironmentMany large estuaries are threatened by intensifying hypoxia. However, due to the limited duration of available observations, uncertainties persist regarding the level of contemporary hypoxia intensity in a longer-term context and the relative ...
Hui Sheng +9 more
doaj +1 more source
The Cerebellum and SIDS: Disordered Breathing in a Mouse Model of Developmental Cerebellar Purkinje Cell Loss during Recovery from Hypercarbia. [PDF]
, 2016 The cerebellum assists coordination of somatomotor, respiratory, and autonomic actions. Purkinje cell alterations or loss appear in sudden infant death and sudden death in epilepsy victims, possibly contributing to the fatal event. We evaluated breathing
Calton, Michele A +4 more
core +2 more sources