Results 61 to 70 of about 40,558 (303)

The Usefulness of Serum Brain Damage Biomarkers in Detection and Evaluation of Hypoxic Ischemic Encephalopathy in Calves with Perinatal Asphyxia

open access: yesAnimals, 2022
The purpose of the present study was to determine hypoxic brain damage in calves with perinatal asphyxia using brain-specific damage biomarkers. Ten healthy and 25 calves with perinatal asphyxia were enrolled in the study.
Mahmut Ok   +10 more
doaj   +1 more source

Pediatric Neuropalliative Medicine Clinic: Five‐Year Data Characterizing a Novel Model of Outpatient Care

open access: yesAnnals of the Child Neurology Society, EarlyView.
ABSTRACT Objective Pediatric neuropalliative medicine (PNPM) is a recently developed area of subspecialty neurology practice focused on supporting the complex emotional, psychological, and physical aspects of caring for a child with serious neurological disease.
Lauren Treat   +2 more
wiley   +1 more source

Postasphyxial Hypoxic-Ischemic Encephalopathy

open access: yesPediatric Neurology Briefs, 1997
Models of association between risk factors and severe adverse outcome within 4 hours of birth were determined in 178 infants with postasphyxiai hypoxic-ischemic encephalopathy (PA-HIE) admitted consecutively between 1985 and 1992 to the regional referral
J Gordon Millichap
doaj   +1 more source

Early changes in pro-inflammatory cytokine levels in neonates with encephalopathy are associated with remote epilepsy. [PDF]

open access: yes, 2019
BackgroundNeonatal seizures are associated with adverse neurologic sequelae including epilepsy in childhood. Here we aim to determine whether levels of cytokines in neonates with brain injury are associated with acute symptomatic seizures or remote ...
Barkovich, A James   +6 more
core  

Role of Antioxidants in Neonatal Hypoxic–Ischemic Brain Injury: New Therapeutic Approaches [PDF]

open access: yes, 2017
Hypoxic-ischemic brain damage is an alarming health and economic problem in spite of the advances in neonatal care. It can cause mortality or detrimental neurological disorders such as cerebral palsy, motor impairment and cognitive deficits in neonates ...
Arteaga Cabeza, Olatz   +5 more
core   +3 more sources

Evolution of the European Medicines Agency clinical guidelines for epilepsy drug development between 2010 and 2025: A comparative analysis by the ILAE Task Force on Regulatory Affairs

open access: yesEpilepsia, EarlyView.
Abstract Objective The latest European Medicines Agency (EMA) guideline on the clinical investigation of medicines to treat epileptic disorders was adopted by the EMA Committee for Medicinal Products for Human Use in 2025. We compared this guideline with the previous version (2010), highlighting areas where significant revisions were introduced ...
Stéphane Auvin   +7 more
wiley   +1 more source

Restricted diffusion in the corpus callosum: A neuroradiological marker in hypoxic–ischemic encephalopathy

open access: yesIndian Journal of Radiology and Imaging, 2016
Background: Restricted diffusion within the splenium of the corpus callosum has been described by other authors in various conditions, however, restricted diffusion in the entire corpus callosum or isolated involvement of the splenium, genu, or body has ...
Alok Kale, Priscilla Joshi, A Kelkar
doaj   +1 more source

Advantages of Bayesian monitoring methods in deciding whether and when to stop a clinical trial: an example of a neonatal cooling trial. [PDF]

open access: yes, 2016
BackgroundDecisions to stop randomized trials are often based on traditional P value thresholds and are often unconvincing to clinicians. To familiarize clinical investigators with the application and advantages of Bayesian monitoring methods, we ...
Bell, Edward F   +6 more
core  

Brain injury due to persistent hyperinsulinemic hypoglycemia of infancy [PDF]

open access: yes, 2007
A
De Visschere, Pieter   +3 more
core   +2 more sources

Long‐term safety of early discontinuation of antiseizure medication after resolution of acute provoked neonatal seizures

open access: yesEpilepsia, EarlyView.
Abstract Objective To assess long‐term safety of antiseizure medication (ASM) discontinuation after resolution of acute provoked neonatal seizures and prior to hospital discharge. Methods Prospective, observational, comparative effectiveness cohort study of neonates with acute provoked seizures born from July 2015 to March 2018, and followed until ...
Hannah C. Glass   +16 more
wiley   +1 more source

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