Results 61 to 70 of about 343,763 (246)

Data‐Driven Insights into Hyperkinetic Disorders in Neurodevelopmental Syndromes and Epileptic Encephalopathies

Movement Disorders Clinical Practice, EarlyView.
Abstract Background Childhood‐onset hyperkinetic movement disorders occur in a range of genetic conditions. Recently, there has been an increase in recognition of hyperkinetic movement disorders, mainly dystonia, chorea and dyskinesia, with monogenic conditions associated with neurodevelopmental delay (NDD) and also with developmental and epileptic ...
Hugo Morales‐Briceño, Shekeeb S. Mohammad, Rajeshwar Reddy Angiti, Velda Han, Michel Tchan, Russell C. Dale, Victor S.C. Fung   +6 more
wiley   +1 more source

Inflammatory responses in hypoxic ischemic encephalopathy [PDF]

Acta Pharmacologica Sinica, 2013
Inflammation plays a critical role in mediating brain injury induced by neonatal hypoxic ischemic encephalopathy (HIE). The mechanisms underlying inflammatory responses to ischemia may be shared by neonatal and adult brains; however, HIE exhibits a unique inflammation phenotype that results from the immaturity of the neonatal immune system. This review
Liu, Fudong, Mccullough, Louise D
openaire   +2 more sources

Repurposing antimicrobial agents for neuroprotection: Mechanisms, clinical potential, and challenges

Neuroprotection, EarlyView.
Antimicrobial agents exert neuroprotective effects through modulation of interconnected pathways. Tetracyclines, macrolides, antimalarial agents, sulfones, and antiparasitic agents suppress neuroinflammation, oxidative stress, and apoptosis while preserving mitochondrial function and neurotransmission.
Mohammad Amin Manavi, Mohammadreza Salehi, Razieh Mohammad Jafari, Ramin Goudarzi, Saman Khosravi, Ahmad Reza Dehpour   +5 more
wiley   +1 more source

Restricted diffusion in the corpus callosum: A neuroradiological marker in hypoxic–ischemic encephalopathy

Indian Journal of Radiology and Imaging, 2016
Background: Restricted diffusion within the splenium of the corpus callosum has been described by other authors in various conditions, however, restricted diffusion in the entire corpus callosum or isolated involvement of the splenium, genu, or body has ...
Alok Kale, Priscilla Joshi, A Kelkar
doaj   +1 more source

Potential biomarkers for hypoxic–ischemic encephalopathy [PDF]

Seminars in Fetal and Neonatal Medicine, 2010
Cerebral hypothermia reduces brain injury and improves behavioral recovery after hypoxia-ischemia (HI) at birth. However, using current enrolment criteria many infants are not helped, and conversely, a significant proportion of control infants survive without disability. In order to further improve treatment we need better biomarkers of injury. A 'true'
L, Bennet, L, Booth, A J, Gunn
openaire   +2 more sources

Chronic high‐altitude exposure and intracerebral hemorrhage: A novel perspective from the vascular‐immune‐neuronal network

Neuroprotection, EarlyView.
Long‐term chronic high‐altitude hypobaric hypoxia increases susceptibility to ICH, particularly among migrant populations lacking EPAS1/SENP1 adaptive genetic variants relative to high‐altitude indigenous residents. Persistent hypoxia initiates blood–brain barrier (BBB) breakdown, aberrant glial and immune activation, and progressive neuronal injury ...
Rongsu Huang, Linjie Wei, Mingxi Li, Bo Wu, Rongjian Ouyang, Gang Zhu, Yujie Chen   +6 more
wiley   +1 more source

Outcome Factors in Hypoxic Ischemic Encephalopathy

, 2002
The predictive value of history, examination, Glasgow Coma Scale (GCS) scores, EEG and sensory evoked potentials (SEP) in the prognosis of children with acute hypoxic-ischemic encephalopathy (HIE) was evaluated at the University Hospital of Lille ...
J Gordon Millichap
core   +1 more source

The Performance of Selective Screening Ultrasound to Detect the Small‐for‐Gestational‐Age Foetus: A Prospective Cohort Study Nested Within the DESiGN Randomised Control Trial

BJOG: An International Journal of Obstetrics &Gynaecology, EarlyView.
ABSTRACT Objective Evidence on the performance of foetal growth ultrasound parameters to detect the Small‐for‐Gestational‐Age (SGA) foetus for a selective cohort is limited. We report the performance of estimated foetal weight under the 10th percentile (EFW < 10th) at the last selective screening ultrasound to detect SGA based on gestational age of ...
Charles Arcus, James Elhindi, Chivon Winsloe, Andrew Copas, Sophie Relph, Annette Briley, Kirstie Coxon, Mark Johnson, Asma Khalil, Deborah A. Lawlor, Christoph Lees, Neil Marlow, Louise Page, Andrew Shennan, Jane Sandall, Tanya Nippita, Matias C. Vieira, Dharmintra Pasupathy   +17 more
wiley   +1 more source

Hypoxic-Ischemic Encephalopathy and Infantile Spasms

, 2014
Investigators at UCSF, British Columbia, and Toronto studied the pattern and areas of brain injury on MRI at third day of life of children with infantile spasms following neonatal hypoxic-ischemic encephalopathy (H-IE)
J Gordon Millichap
core   +1 more source

The BLISS cluster randomised controlled trial of the effect of 'active dissemination of information' on standards of care for premature babies in England (BEADI) study protocol [ISRCTN89683698]. [PDF]

, 2007
BACKGROUND: Gaps between research knowledge and practice have been consistently reported. Traditional ways of communicating information have limited impact on practice changes.
Clemens, Felicity, Weindling Michael, Houston, Rosie, Weindling, Michael, Clemens, F, Elbourne, Diana, Edward Peck, Davidson, Deborah, Lavis, John, Acolet Dominique, Acolet, Dominique, Felicity Clemens, Lavis John, Acolet, D, Houston, R, Elbourne, D, Peck, Edward, Dominique Acolet, Deborah Davidson, Diana Elbourne, Lavis, J, Jelphs, Kim, Houston Rosie, John Lavis, Rosie Houston, Davidson Deborah, Elbourne Diana, Weindling, M, Clemens Felicity, Jelphs Kim, Peck Edward, Michael Weindling, Kim Jelphs   +32 more
core   +1 more source