Results 51 to 60 of about 343,763 (246)

Perinatal outcomes in normotensive versus hypertensive HELLP syndrome

open access: yesInternational Journal of Gynecology &Obstetrics, EarlyView.
Abstract Objective To compare maternal and neonatal outcomes between women with hemolysis, elevated liver enzymes, and low platelets (HELLP) syndrome with and without associated hypertension. Methods This was a retrospective cohort study at a tertiary university‐affiliated medical center including all singleton HELLP cases >24 weeks gestation (January ...
Matan Anteby   +4 more
wiley   +1 more source

Time of day/unit busyness at birth and perinatal hypoxia and or moderate to severe hypoxic ischemic encephalopathy a cohort study

open access: yesThe Journal of Maternal-Fetal & Neonatal Medicine
Objectives To investigate the potential link between nighttime births, unit busyness, and the incidence of perinatal hypoxia or moderate-to-severe hypoxic-ischemic encephalopathy.Methods Retrospective cohort study with nested case control study of all ...
Stephen Wood   +3 more
doaj   +1 more source

Compare Serum VCAM‐1, NSE, Procalcitonin in Predict Sepsis Induced Encephalopathy in Septic Patients

open access: yesJournal of Clinical Laboratory Analysis, EarlyView.
Serum VCAM‐1 is associated with septic encephalopathy in the first 7 days of sepsis. NSE and procalcitonin were not associated with septic encephalopathy. ABSTRACT Background Sepsis‐associated encephalopathy (SAE) is a common complication of severe sepsis. Increased concentration of Vascular Cell Adhesion Molecule 1 (VCAM‐1) is associated with SAE in a
Chun‐Fu Lin   +2 more
wiley   +1 more source

Role of mitochondria in neonatal hypoxic-ischemic encephalopathy [PDF]

open access: yes
Neonatal hypoxic-ischemic encephalopathy, an important cause of death as well as long-term disability in survivors, is caused by oxygen and glucose deprivation, and limited blood flow.
Lu, Cheng, Kong, Weijing
core   +1 more source

Role of Matrix Metalloproteinase-9 in Neonatal Hypoxic-Ischemic Encephalopathy [PDF]

open access: yes, 2019
BACKGROUND: Neonatal encephalopathy is a heterogeneous syndrome characterised by signs of central nervous system dysfunction in the newborn. Matrix metalloproteinase-9(MMP-9) increases the blood-brain barrier permeability, and their inhibitors can reduce
Salah, Mohab M.   +5 more
core   +1 more source

Trial of erythropoietin for hypoxic-ischemic encephalopathy in newborns [PDF]

open access: yes, 2022
BACKGROUND: Neonatal hypoxic-ischemic encephalopathy is an important cause of death as well as long-term disability in survivors. Erythropoietin has been hypothesized to have neuroprotective effects in infants with hypoxic-ischemic encephalopathy, but ...
Rao, Rakesh   +4 more
core   +1 more source

Hypoxic ischaemic encephalopathy

open access: yes, 2023
Neonatal encephalopathy (NE) is a heterogeneous clinical syndrome manifesting as impaired neurological dysfunction, including impaired consciousness or seizures, difficulty in initiating and maintaining breathing, loss of reflexes, and tonus in newborns ...
Toptan, Handan Hakyemez, Tunç, Gaffari
core   +1 more source

Hypothermia for newborns with hypoxic-ischemic encephalopathy [PDF]

open access: yesPaediatrics & Child Health, 2018
Therapeutic hypothermia is a standard of care for infants ≥36 weeks gestational age (GA) with moderate-to-severe hypoxic-ischemic encephalopathy. Because some studies included infants born at 35 weeks GA, hypothermia should be considered if they meet other criteria. Cooling for infants
Brigitte, Lemyre, Vann, Chau
openaire   +2 more sources

Comparison of Cranial Ultrasound and Amplitude‐Integrated Electroencephalography in Predicting Neurodevelopmental Outcomes in Neonates With Hypoxic–Ischemic Encephalopathy: A Systematic Review and Meta‐Analysis

open access: yesJournal of Clinical Ultrasound, EarlyView.
In neonates with hypoxic–ischemic encephalopathy (HIE), adverse neurodevelopmental outcomes (NDO) remain common. Amplitude‐integrated EEG demonstrates strong prognostic value for early prediction, while cranial ultrasound (cUS) provides complementary but less definitive information.
Meirong Shu   +6 more
wiley   +1 more source

Mast Cell-Microglia Crosstalk Drives Aberrant Synaptic Pruning Through PAR-2/MAPK/NF-κB Signaling in Neonatal Hypoxic-Ischemic Encephalopathy. [PDF]

open access: yesCNS Neurosci Ther
Following neonatal hypoxic–ischemic injury, hippocampal mast cell degranulation releases tryptase, which activates microglial PAR‐2 receptors to trigger p38 MAPK/NF‐κB signaling and drive aberrant synaptic engulfment. This pathological mast cell–microglia crosstalk leads to progressive synaptic loss and long‐term cognitive impairment.
Yang Y   +13 more
europepmc   +2 more sources

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