Late Presentation of Hypoxic Injury of Brain in an Infant
Perinatal asphyxia is one of the leading causes of hypoxic-ischemic encephalopathy. In a developing country like Nepal, home delivery is the leading cause of perinatal asphyxia. Neuroimaging remains the diagnostic modality of choice.
Pradeep Raj Regmi +4 more
doaj +1 more source
Metabolic Changes Following Perinatal Asphyxia: Role of Astrocytes and Their Interaction with Neurons [PDF]
Perinatal Asphyxia (PA) represents an important cause of severe neurological deficits including delayed mental and motor development, epilepsy, major cognitive deficits and blindness.
Barreto, George E. +5 more
core +1 more source
Ultrasonographic Evaluation of the Neonatal Brain in Cases of Birth Asphyxia [PDF]
Introduction: Hypoxic ischemic encephalopathy (HIE) is a common condition in newborns as a result of birth asphyxia. Affected neonates display a number of clinical features by which the condition may be suspected.
Susmita Giri +2 more
doaj +1 more source
Early changes in brain structure correlate with language outcomes in children with neonatal encephalopathy. [PDF]
Global patterns of brain injury correlate with motor, cognitive, and language outcomes in survivors of neonatal encephalopathy (NE). However, it is still unclear whether local changes in brain structure predict specific deficits.
Barkovich, A James +9 more
core +2 more sources
MicroRNA-210 Suppresses Junction Proteins and Disrupts Blood-Brain Barrier Integrity in Neonatal Rat Hypoxic-Ischemic Brain Injury. [PDF]
Cerebral edema, primarily caused by disruption of the blood-brain barrier (BBB), is one of the serious complications associated with brain injury in neonatal hypoxic-ischemic encephalopathy (HIE).
Dasgupta, Chiranjib +4 more
core +2 more sources
[INLINE:1] Neonatal hypoxic-ischemic encephalopathy is often associated with permanent cerebral palsy, neurosensory impairments, and cognitive deficits, and there is no effective treatment for complications related to hypoxic-ischemic encephalopathy. The
Lulu Xue +10 more
doaj +1 more source
Metabolomics application in maternal-fetal medicine [PDF]
Metabolomics in maternal-fetal medicine is still an "embryonic" science. However, there is already an increasing interest in metabolome of normal and complicated pregnancies, and neonatal outcomes. Tissues used for metabolomics interrogations of pregnant
Atzori, L +4 more
core +4 more sources
Barrier mechanisms in neonatal stroke. [PDF]
Clinical data continue to reveal that the incidence of perinatal stroke is high, similar to that in the elderly. Perinatal stroke leads to significant morbidity and severe long-term neurological and cognitive deficits, including cerebral palsy ...
Chip, Sophorn +2 more
core +2 more sources
Hypothermia for hypoxic–ischemic encephalopathy [PDF]
Moderate to severe hypoxic-ischemic injury in newborn infants, manifested as encephalopathy immediately or within hours after birth, is associated with a high risk of either death or a lifetime with disability. In recent multicenter clinical trials, hypothermia initiated within the first 6 postnatal hours has emerged as a therapy that reduces the risk ...
C Michael, Cotten, Seetha, Shankaran
openaire +2 more sources
Effects of therapeutic hypothermia on white matter injury from murine neonatal hypoxia-ischemia. [PDF]
BackgroundTherapeutic hypothermia (TH) is the standard of care for neonates with hypoxic-ischemic encephalopathy, but it is not fully protective in the clinical setting.
Ferriero, Donna M +4 more
core +2 more sources

