Results 31 to 40 of about 3,535 (212)

Infantile Spasms: An Update on Pre-Clinical Models and EEG Mechanisms

open access: yesChildren, 2020
Infantile spasms (IS) is an epileptic encephalopathy with unique clinical and electrographic features, which affects children in the middle of the first year of life. The pathophysiology of IS remains incompletely understood, despite the heterogeneity of
Remi Janicot   +2 more
doaj   +1 more source

Interpretation of electroencephalography in infants

open access: yesЭпилепсия и пароксизмальные состояния, 2020
Aim: Based on published reports and our own observations, we aimed to assign the graphical elements of EEG into normal and abnormal groups and then identify up to five main graphic elements in each group to facilitate visual analysis and interpretation ...
A. G. Koshchavtsev, S. V. Grechanyi
doaj   +1 more source

Clinical Features and Treatment Efficacy in Mutation-Related Epileptic Encephalopathy in the Infant [PDF]

open access: yesAnnals of Child Neurology, 2019
Purpose Mutations in the cyclin-dependent kinase-like 5 (CDKL5) gene are associated with epileptic encephalopathy and severe cognitive impairment. We aim to characterize the association between this gene and treatment efficacy. Methods We retrospectively
Chung Mo Koo   +6 more
doaj   +1 more source

ACTH Efficacy in Symptomatic Infantile Spasms

open access: yesPediatric Neurology Briefs, 1994
A retrospective evaluation of 26 case records of patients with diagnoses of symptomatic infantile spasms and classic hypsarrhythmia is reported from the Division of Pediatric Neurology, University of Minnesota Medical School, Minneapolis, MN.
J Gordon Millichap
doaj   +1 more source

Inter‐rater reliability and clinical utility of the BASED score in infantile epileptic spasms syndrome

open access: yesEpileptic Disorders, EarlyView.
Abstract Objective Hypsarrhythmia is the classical EEG pattern of children with infantile epileptic spasms syndrome (IESS). Multifocal spikes, slow waves of large amplitude, and chaoticity are its main characteristics, but these lack clear definitions, and the interrater reliability (IRR) is poor.
T. P. Cramer   +4 more
wiley   +1 more source

West Syndrome Remission Following Acute Viral Infection

open access: yesPediatric Neurology Briefs, 2011
Researchers at Nihon University School of Medicine, Tokyo, Japan, report 11 children with intractable epilepsy (West syndrome in 6 and myoclonic seizures in 5) who showed clinical and electrographic improvement following acute viral infection.
J Gordon Millichap
doaj   +1 more source

Brain Magnetic Resonance Imaging Findings in Infantile Spasms

open access: yesNeurology International, 2022
Background: Infantile spasms are an age-specific epileptic disorder. They occur in infancy and early childhood. They can be caused by multiple etiologies. Structural abnormalities represent an important cause of infantile spasms. Brain magnetic resonance
Osama Y. Muthaffar
doaj   +1 more source

West Syndrome in an Infant with Complete Corpus Callosal Agenesis

open access: yesArchives of Medicine and Health Sciences
West syndrome is a severe form of epilepsy with onset in infancy and early childhood. The characteristic triad described includes infantile spasms (IS), an abnormal electroencephalogram (EEG) pattern referred to as hypsarrhythmia, and developmental ...
S. Sheetal   +3 more
doaj   +1 more source

ACTH vs Vigabatrin in Infantile Spasms

open access: yesPediatric Neurology Briefs, 1999
The comparative efficacy and safety of ACTH (110 IU/m2 once daily for 15 days) and vigabatrin (100-150 mg/kg/daily in bid doses) was evaluated by a retrospective analysis of medical records of 42 infants (21 in each group) with infantile spasms and ...
J Gordon Millichap
doaj   +1 more source

The impact of hypsarrhythmia on infantile spasms treatment response: Observational cohort study from the National Infantile Spasms Consortium

open access: yesEpilepsia, 2017
The multicenter National Infantile Spasms Consortium prospective cohort was used to compare outcomes and phenotypic features of patients with infantile spasms with and without hypsarrhythmia.
S. Demarest   +21 more
semanticscholar   +1 more source

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