Results 21 to 30 of about 683 (144)
Epileptic Encephalopathies, CDKL5 Mutations, and Infantile Spasms
Pediatric Neurology Briefs, 2012 Researchers at the Mayo Clinic, Rochester, MN performed retrospective chart reviews of 6 children with epilepsy and CDKL5 mutations.
J Gordon Millichap
doaj +1 more source
Developmental Outcome of West Syndrome
Pediatric Neurology Briefs, 2007 Medical records of 32 patients with cryptogenic West syndrome were reviewed for factors correlating with developmental outcome in a study at Saitama Children’s Medical Center, and the Jikei University School of Medicine, Tokyo, Japan.
J Gordon Millichap
doaj +1 more source
X-Linked Mental Retardation and Epilepsy Syndrome
Pediatric Neurology Briefs, 2002 A kindred of 7 affected male infants with an X-linked mental retardation and epilepsy syndrome (XMRE), distinct from X-linked West and other mental retardation-epilepsy syndromes, is reported from the University of Michigan, Ann Arbor, MI.
J Gordon Millichap
doaj +1 more source
Improving the inter-rater agreement of hypsarrhythmia using a simplified EEG grading scale for children with infantile spasms [PDF]
, 2015 BackgroundThere is poor inter-rater agreement in determining the presence or absence of hypsarrhythmia among patients with infantile spasms. Yet, remission of hypsarrhythmia has been used as a clinical and research outcome measure. Two important features
Islam, Monica P. +7 more
core +1 more source
Frontiers in PharmacologyBackgroundInfantile epileptic spasm syndrome (IESS), a rare age-specific epileptic encephalopathy, exhibits limited therapeutic efficacy, with approximately 50% of patients showing resistance to adrenocorticotropic hormone (ACTH) monotherapy.
Ka-Na Lin +9 more
doaj +1 more source
Hypsarrhythmia paroxysm index: A tool for early prediction of infantile spasms
, 2021 Recurrence of infantile spasms (ISs) is common subsequent to treatment with adrenocorticotropic hormone (ACTH) for West syndrome, and prolonged hypsarrhythmia results in psychomotor deterioration.
Altunel, Attila +2 more
core +1 more source
, 2022 Purpose The present study would like to investigate the effect of hypsarrhythmia paroxysms on neurological examination findings. Material and Method This study enrolled 48 children with normal cranial magnetic resonance imaging (cMRI) findings who were ...
Attila Altunel +9 more
core +1 more source
Infantile Spasms: An Update on Pre-Clinical Models and EEG Mechanisms
Children, 2020 Infantile spasms (IS) is an epileptic encephalopathy with unique clinical and electrographic features, which affects children in the middle of the first year of life. The pathophysiology of IS remains incompletely understood, despite the heterogeneity of
Remi Janicot +2 more
doaj +1 more source
Interpretation of electroencephalography in infants
Эпилепсия и пароксизмальные состояния, 2020 Aim: Based on published reports and our own observations, we aimed to assign the graphical elements of EEG into normal and abnormal groups and then identify up to five main graphic elements in each group to facilitate visual analysis and interpretation ...
A. G. Koshchavtsev, S. V. Grechanyi
doaj +1 more source
Clinical Features and Treatment Efficacy in Mutation-Related Epileptic Encephalopathy in the Infant [PDF]
Annals of Child Neurology, 2019 Purpose Mutations in the cyclin-dependent kinase-like 5 (CDKL5) gene are associated with epileptic encephalopathy and severe cognitive impairment. We aim to characterize the association between this gene and treatment efficacy. Methods We retrospectively
Chung Mo Koo +6 more
doaj +1 more source