Results 51 to 60 of about 23,030,725 (282)

Folding and Unfolding of Exogenous G-Rich Oligonucleotides in Live Cells by Fluorescence Lifetime Imaging Microscopy of o-BMVC Fluorescent Probe

Molecules, 2021
Guanine-rich oligonucleotides (GROs) can self-associate to form G-quadruplex (G4) structures that have been extensively studied in vitro. To translate the G4 study from in vitro to in live cells, here fluorescence lifetime imaging microscopy (FLIM) of an
Ting-Yuan Tseng, Chiung-Lin Wang, Wei-Chun Huang, Ta-Chau Chang   +3 more
doaj   +1 more source

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

FEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell, Thomas Walther, Egbert Hoiczyk   +2 more
wiley   +1 more source

AGN feedback on molecular gas reservoirs in quasars at z ~ 2.4 [PDF]

Astronomy & Astrophysics, 2017
We present new ALMA observations aimed at mapping molecular gas reservoirs through the CO(3-2) transition in three quasars at $z\simeq2.4$, LBQS 0109+0213, 2QZ J002830.4-281706, and [HB89] 0329-385. Previous [OIII]5007 observations of these quasars showed evidence for ionised outflows quenching star formation in their host galaxies.
Carniani, S., Marconi, A., Maiolino, R., Feruglio, C., Brusa, M., Cresci, G., Cano-Díaz, M., Cicone, C., Balmaverde, B., Fiore, F., Ferrara, A., Gallerani, S., La Franca, F., Mainieri, V., Mannucci, F., Netzer, H., Piconcelli, E., Sani, E., Schneider, R., Shemmer, O., Testi, L.   +20 more
openaire   +5 more sources

Probing large-scale ionizing background fluctuation with Lyman α forest and galaxy cross-correlation at z = 2.4

Monthly Notices of the Royal Astronomical Society, 2023
ABSTRACT The amplitude of the metagalactic ultraviolet background (UVB) at large scales is impacted by two factors. First, it naturally attenuates at scales larger than mean-free path of UVB photons due to the absorption by neutral intergalactic medium.
Heyang Long, Christopher M Hirata
openaire   +2 more sources

Chiral separation of chloroalkanes with the chromatographic column onboard Martian rovers

FEBS Letters, EarlyView.
Computer image of the Rosalind Franklin Rover of ESA's ExoMars mission. ExoMars is scheduled to land on planet Mars in Oxia Planum in 2029. This area represents an interesting spot to look for biosignatures. Investigations of ExoMars include measurement on molecular chirality. We show that chiral chloroalkanes, that have been identified on Mars, can be
Asma Merzougui, Agnes Banreti, Armelle L. Ernst, Guillaume Leseigneur, Uwe J. Meierhenrich   +4 more
wiley   +1 more source

El País Valenciano de Joan Fuster i la descripció del territori: producció textual, traducció i recontextualització [PDF]

, 2016
Joan Fuster (1922-1992) és considerat l'assagista català més important del segle XX. La seva obra constitueix una de les aportacions intel·lectuals més suggestives produïdes al País Valencià i des del País Valencià, amb una projecció no menyspreable ...
Pérez i Grau, Daniel
core   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

Vitamin D Receptor Gene Variants Susceptible to Osteoporosis in Arab Post-Menopausal Women

Current Issues in Molecular Biology, 2021
Post-menopausal osteoporosis (PMO) is a multifactorial bone disorder in elderly women. Various vitamin D receptor (VDR) gene variants have been studied and associated with osteoporosis in other populations, but not in a homogenous Arab ethnic group ...
Mohammed. G. A. Ansari, Abdul Khader Mohammed, Kaiser A. Wani, Syed D. Hussain, Abdullah M. Alnaami, Saba Abdi, Naji J. Aljohani, Nasser M. Al-Daghri   +7 more
doaj   +1 more source

Searching for the shadows of giants – II. The effect of local ionization on the Ly α absorption signatures of protoclusters at redshift z ∼ 2.4

Monthly Notices of the Royal Astronomical Society, 2021
ABSTRACT Local variations in the intergalactic medium (IGM) neutral hydrogen fraction will affect the Ly α absorption signature of protoclusters identified in tomographic surveys. Using the IllustrisTNG simulations, we investigate how the AGN proximity effect and hot, collisionally ionized gas arising from gravitational infall and black ...
Joel S A Miller, James S Bolton, Nina A Hatch   +2 more
openaire   +2 more sources

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source