Results 41 to 50 of about 3,817 (149)
I32E and V36K double mutation in beta2-sheet abrogates amyloid beta peptide toxicity.
Alzheimer's disease (AD) is the most common cause of dementia in the elderly, wherein, the accumulation of amyloid beta (Abeta) peptide as cytotoxic oligomers leads to neuropathologic changes. Transgenic mice with brain Abeta plaques immunized with aggregated Abeta have reduced amyloid burden and improved cognitive functions.
Sarada, Subramanian +2 more
openaire +1 more source
The paper will discuss the problem of pensioner poverty in Poland, its elimination, as well as the question of the impact of social policy measures on the Sustainable Development Goals (SDGs) called ‘no poverty’.
Palimąka Karolina, Wronka Klaudia
doaj +1 more source
Abstract To continue to support long‐term, ongoing science curriculum and instruction reform efforts in the United States, there is a significant need to be able to reliably measure teachers’ discourse‐rich, inquiry‐based instruction. In this external validation study, we present the Discourse in Inquiry Science Classrooms Version 2.0 (DiISC 2.0) as a ...
Elizabeth Lewis +6 more
wiley +1 more source
This paper examines the effect of financial inclusion on per capita household consumption expenditures in sub-Saharan Africa. It uses data from 28 countries over the period 2004–2022 and an endogenous threshold dynamic panel model for econometric ...
Ahmat-Tidjani Mahamat Ibrahim
doaj +1 more source
Abstract Since 2007, the European Union has devoted significant time and energy to the production and dissemination of new statistics designed to monitor social and environmental trends of various types. These initiatives have often been presented as part of a broader ‘beyond GDP agenda’, which challenges the centrality of economic growth, as measured ...
Christopher Holmes, Agnieszka Widuto
wiley +1 more source
Peptide Sequencing With Single Acid Resolution Using a Sub‐Nanometer Diameter Pore
To sequence a single molecule of Aβ1−42–sodium dodecyl sulfate (SDS), the aggregate is forced through a sub‐nanopore 0.4 nm in diameter spanning a 4.0 nm thick membrane. The figure is a visual molecular dynamics (VMD) snapshot depicting the translocation of Aβ1−42–SDS through the pore; only the peptide, the SDS, the Na+ (yellow/green) and Cl− (cyan ...
Apurba Paul +8 more
wiley +1 more source
A strategy utilizing high‐energy ion beam technology to engineer defects in layered double hydroxide (LDH) nanosheets enables the high loading of non‐noble metal Mo single atoms. The synergistic effect between oxygen vacancies and single atoms promotes a novel mechanism for lattice oxygen activation, thereby significantly enhancing the oxygen evolution
Shixin Wu +9 more
wiley +1 more source
ABSTRACT As new regulations emerge to address deforestation and unsustainable land use, their interaction with existing national frameworks remains uncertain. This study examines the (in)coherence between the European Union Regulation on deforestation‐free products (EUDR) and domestic deforestation and land use regulations in Brazil, Cameroon and Gabon.
R. F. Ziegert +5 more
wiley +1 more source
ThreadMonitor: Low‐Overhead Data Race Detection Using Intel Processor Trace
ABSTRACT Data races are among the most difficult multithreading bugs to find, due to their non‐deterministic nature. This and the increasing popularity of multithreaded programming have led to the need for practical automated data race detection. In this context, dynamic data race detectors have received more attention, compared to static tools, owing ...
Farzam Dorostkar +3 more
wiley +1 more source
Abstract Six sets of 48 maize (Zea mays L.) inbred lines, and their 96 single crosses generated using the North Carolina Mating Design II system, were evaluated for resistance to gray leaf spot (GLS). The aim of the study was to assess the implications of combining ability, heterotic effects, and potence ratio in breeding for GLS resistance in maize ...
James O. Nyanapah +4 more
wiley +1 more source

