Results 11 to 20 of about 4,813 (214)

The impact of PA/I38 substitutions and PA polymorphisms on the susceptibility of zoonotic influenza A viruses to baloxavir [PDF]

Archives of Virology
AbstractGenetic reassortment of avian, swine, and human influenza A viruses (IAVs) poses potential pandemic risks. Surveillance is important for influenza pandemic preparedness, but the susceptibility of zoonotic IAVs to the cap-dependent endonuclease inhibitor baloxavir acid (BXA) has not been thoroughly researched. Although an amino acid substitution
Takao Shishido, Hiroshi Kida, Keiichi Taniguchi   +2 more
exaly   +5 more sources

Treatment-Emergent Influenza Virus Polymerase Acidic Substitutions Independent of Those at I38 Associated With Reduced Baloxavir Susceptibility and Virus Rebound in Trials of Baloxavir Marboxil [PDF]

Journal of Infectious Diseases, 2020
AbstractInfluenza viruses harboring treatment-emergent I38F/M/N/T substitutions in the polymerase acidic (PA) endonuclease exhibited reduced susceptibility to baloxavir and were associated with virus rebound and variable clinical response in clinical trials.
William L, Ince, Fraser B, Smith, Julian J, O'Rear, Michael, Thomson   +3 more
exaly   +4 more sources

I38 Rheumatology in Interesting Times [PDF]

Rheumatology, 2016
Jane Dacre
exaly   +3 more sources

I38. BIOLOGICS AND SAFETY ISSUES GUIDELINE [PDF]

Rheumatology, 2017
C. Holroyd
exaly   +3 more sources

I38. Innate Lymphoid Cells and Stroma in Inflammation and Tissue Pathology [PDF]

Rheumatology, 2015
M. Coles
exaly   +3 more sources

Accuracy of data routinely collected by Australian hospitals for identifying infective endocarditis, causative organisms and clinical outcomes: a diagnostic accuracy study. [PDF]

Intern Med J
Abstract Background Infective endocarditis (IE) is a life‐threatening condition, and the surveillance of the incidence is important for monitoring disease trends. Administrative data routinely collected by hospitals offer a feasible and inexpensive method for surveillance of patients with IE, yet the accuracy of coding of IE, causative organisms and ...
Vaidya R, Kataria N, Zou J, Li Q, Khawaja S, Dang T, Smith S, Lau K, Denman R, Wee Y, Learmouth B, Janoschka B, Sedgwick J, Horvath R, Ranasinghe I.   +14 more
europepmc   +2 more sources

I38. From Bark to B Cells [PDF]

Rheumatology, 2014
R. Watts
openaire   +2 more sources

Rural pension policy in Brazil: performance, challenges, and reform proposals [PDF]

Brazilian Journal of Political Economy
This article analyzes the differential treatment provided by Brazil’s pension policy to rural workers, an issue heightened by the recent pension reforms.
Fabio Giambiagi, Rogério Nagamine Costanzi, Otávio José Guerci Sidone   +2 more
doaj   +3 more sources

The declining mental health of the young and the global disappearance of the unhappiness hump shape in age.

PLoS ONE
Across many studies subjective well-being has followed a U-shape in age, declining until people reach middle-age, only to rebound subsequently. Ill-being has followed a mirror-imaged hump-shape.
David G Blanchflower, Alex Bryson, Xiaowei Xu   +2 more
doaj   +2 more sources

An Analysis of the Public Distribution System in Rural Haryana, India

Studia Ekonomiczne i Regionalne, 2023
The present paper aims to analyze the functioning and coverage of the public distribution system in rural Haryana, India.
Devi Seema, Siwach Manoj
doaj   +1 more source