Results 191 to 200 of about 717,375 (275)

A Secular Increase in the Incidence of Islet Autoimmunity Among Colorado Children With Moderate-Risk HLA Genotypes. [PDF]

Diabetes Care
Hohsfield KR, Dong F, Waugh K, Steck AK, Buckner T, Johnson RK, Carry PM, Frohnert B, Rewers M, Norris JM.   +9 more
europepmc   +1 more source

Reversible, Chemically Gated FRET via Ligand‐Activated Acceptors

Advanced Science, EarlyView.
Fluorogen binding turns the compact FAST tag into a tunable FRET acceptor, with ligand chemistry programming spectral overlap and excited‐state lifetimes. Fluorescence‐lifetime imaging reads out energy transfer through the shortened donor lifetime, while simply adding or washing out the dye switches FRET on and off, reversibly mapping the supramodular ...
Nivedita Singh, Smruti Ranjan Nayak, Sanjay Kumar Mohanty, Aishwarya Hanumantharaju, Amala Shaju, Mini Jose, Aravind Penmatsa, Deepak Nair   +7 more
wiley   +1 more source

HLA class I expression and tumor immune infiltration together shape colon cancer immune contexture. [PDF]

Neoplasia
Zhu H, van Nieuwkerk R, van der Kroft S, van Vlierberghe RLP, IJsselsteijn ME, Zuo W, Hviid TVF, Tollenaar RAEM, Vahrmeijer AL, Bedognetti D, Hendrickx WRL, Roelands J, Kuppen PJK.   +12 more
europepmc   +1 more source

Nascent Extracellular Matrix Converts Biomaterial Cues into Cell Fate Decisions

Advanced Science, EarlyView.
This study uncovers a tri‐directional interplay among cells, hydrogels, and their nascent extracellular matrix. Hydrogel norbornene modification alters CD44‐mediated cell–hydrogel interactions, which shape nascent matrix deposition, composition, and spatial organization.
Joshua Y. Liu, Ziqian Yang, Arina E. Velieva, Eleanor M. Plaster, Mingyue Fan, Donia W. Ahmed, Avinava Roy, Pamela Duran, Pamela Panovich, Alexandra S. Piotrowski‐Daspit, Carlos A. Aguilar, Megan L. Killian, Claudia Loebel   +12 more
wiley   +1 more source

Targeted anti-CCP testing to identify people at risk of rheumatoid arthritis in primary care: an early economic evaluation. [PDF]

Rheumatol Adv Pract
Smith AF, Shinkins B, Hensor EMA, Wilson M, Anderson AM, Stack R, Emery P, Mankia K, Siddle HJ.   +8 more
europepmc   +1 more source

Cómo la IA en extracción de metales acelera la economía limpia

El artículo explora cómo la inteligencia artificial (IA) está revolucionando la extracción de metales para la economía limpia. Empresas como Earth AI utilizan IA para predecir la ubicación de depósitos minerales, reduciendo costos y tiempo en la ...
GĚRENS
core  

A Scalable Droplet Microfluidic Platform That Overcomes Large‐Cell Constraints for Long‐Term Plant Cell Culture and Embryogenesis Analysis

Advanced Science, EarlyView.
This work presents a large‐cell‐compatible droplet microfluidic platform that overcomes long‐standing barriers in plant cell culture by enabling high‐fidelity encapsulation, novel multilayer 3D droplet incubation for scalable long‐term culture, and support for the full developmental progression of large plant cells.
Arman Mirmiran, Fangchi Shao, Gregory Datto, Tathansh Joshi, Elizabeth Chatt, Yashar Bashirzadeh, Dan Stessman, Lai Wei, Kuangwen Hsieh, Hena Guo, Tza‐Huei Wang   +10 more
wiley   +1 more source

Galactokinase 1 Positively Regulates Mitochondrial Respiration by Phosphorylating TIMM13 as a Protein Kinase

Advanced Science, EarlyView.
GALK1 acts as a protein kinase beyond the phosphorylation of galactose. GALK1 phosphorylates TIMM13 at Y73 in the cytoplasm. This phosphorylation prevents premature oxidative folding of TIMM13 and ensures its entrance into the intermembrane space of mitochondrion, positively regulating mitochondrial respiration.
Chang Woo Ko, Dongyoon Shin, Junho Park, June Huh, Youngsoo Kim, Jong‐Wan Park   +5 more
wiley   +1 more source

Direct Graft Copolymerization of Cellulose Acetate Membrane with Bio-Based Itaconic Acid for Pollutant Removal from Wastewater. [PDF]

Membranes (Basel)
Abdel-Naby AS, Abo-Ghonaim SS, Alharthi SN, Alhaddad HH, Mu'azu ND.   +4 more
europepmc   +1 more source

Computational and Data‐Driven Strategies for Lignocellulosic Biomass Valorization: From Multiscale Modeling to Digitalized Biorefinery Design

Advanced Science, EarlyView.
This Review critically connects structural recalcitrance, molecular modeling, solvent and catalyst design, pyrolysis, machine learning, reactor simulation, and FAIR digital infrastructure. Emphasis is placed on experimentally validated information transfer across scales, uncertainty and applicability domains, and the recycle, durability, techno ...
Abdullahi Bello Umar, Jiaxian Zheng, Xiangfeng Lin, Hongwu Liao, Haoqian Xu, Yufei Huang, Zaharaddeen Nasiru Garba, Adamu Uzairu, Weiwei Zhao, Zhanhui Yuan   +9 more
wiley   +1 more source