Results 111 to 120 of about 44,950 (250)

Unveiling the Functional Role of KIF21B in Microglia Inflammatory Response

Glia, Volume 74, Issue 9, September 2026.
Microglia express KIF21B in both sexes. KIF21B binds to microglia cytoskeleton; inflammation alters such interaction promoting a phagocytic state in females. In male microglia KIF21B modulates migration. ABSTRACT Microglia are brain immune cells that maintain homeostasis and respond to injury, changing cell morphology to drive inflammation, migration ...
Danny Ganchala, Alvaro Bautista‐Abad, Daniel Pinto‐Benito, Julia Simon‐Areces, Daniela Grassi, Francesco Paolo Ulloa Severino, Maria‐Angeles Arevalo   +6 more
wiley   +1 more source

Identification of secondary microglial formation centers in the human fetal brain. [PDF]

J Exp Med
Song C, Chen X, Ji R, Liu Y, Han Y, Ye F, Zhang L, Li L, Gao L, He Q, Ma L, Saiyin H.   +11 more
europepmc   +1 more source

Conformational diversity in poly‐HAMP arrays and its implications for signal transduction

Protein Science, Volume 35, Issue 9, September 2026.
Abstract Prokaryotic transmembrane receptors are built around a helical coiled‐coil backbone, with sensory, modulatory, and effector domains arranged along its length. The modulatory HAMP domain forms a parallel four‐helix coiled coil integrated into this backbone, typically connecting transmembrane segments with downstream cytosolic domains.
Murray Coles, Carolin P. Ewers, Reinhard Albrecht, Mikel Martinez‐Goikoetxea, Malgorzata Orlowska, Jörg Martin, Andrei N. Lupas, Marcus D. Hartmann, Stanislaw Dunin‐Horkawicz   +8 more
wiley   +1 more source

Indole-3-acetic acid production is rare among gut bacteria and reflects OFOR-driven amino acid oxidation in acetogens. [PDF]

Gut Microbes
DeFeo ME, Liu Y, Zhou Z, Higginbottom SK, Dodd D.   +4 more
europepmc   +1 more source

Artificial Catch Bonds: From Molecular Design to Network Mechanics

ChemSystemsChem, Volume 8, Issue 5, September 2026.
Catch bonds strengthen rather than weaken under force. This review follows the discovery and development of our understanding of this counterintuitive phenomenon, from the molecular mechanisms that produce it to the design rules for engineering it in DNA, proteins, and polymers, and on to the collective network mechanics enabling materials that stiffen
Hengfeng Jiang, Micah Yang, Isaac T. S. Li   +2 more
wiley   +1 more source

Sex- and Region-Specific Glial Reactivity in Hyperthyroid Mice Lacks Correlation With the Noncognitive and Non-Depressive-Like Behavioral Alterations. [PDF]

Brain Behav
Xue Q, Lin Z, Wang Y, Lin X, Yang Y, Wang C, Ye Y, Miao W.   +7 more
europepmc   +1 more source

Increased expression of inflammasome signaling genes and proteins in selective brain regions in the intermediate stage of Alzheimer's disease

Brain Pathology, Volume 36, Issue 5, September 2026.
Neuritic plaques increase in the intermediate stage of Alzheimer's neuropathological change. The intermediate stage of Alzheimer's disease was investigated by transcriptomics and immunohistochemistry. This revealed that inflammasome sensors NLRP1, NLRP3, and AIM2 oligomerize with ASC speck to form the inflammasome complex and initiate the downstream ...
Juan Pablo de Rivero Vaccari, David A. Davis, Andrew P. Sawaya, Susanna P. Garamszegi, Xiaoyan Sun, Ayled Barreda, Helen M. Bramlett, Sakir Humayun Gultekin, W. Dalton Dietrich, Robert W. Keane, Regina T. Vontell   +10 more
wiley   +1 more source

Peripheral Sympathetic Sprouting Drives Neuropathic Pain via Spinal Microglial P2Y12 Activation in a Rat Spinal Nerve Ligation Model. [PDF]

J Pain Res
Yu T, Huang H, Li Z, Yan H.
europepmc   +1 more source

Humanising Web‐Based Learning for Academically Transitioning Students Through Their Voices

European Journal of Education, Volume 61, Issue 3, September 2026.
ABSTRACT Web‐based learning (WBL) has been widely used to support students' learning and has demonstrated its role in boosting students' academic success. Little research has focused on strategies that students can use to humanise this mode of learning, especially academically transitioning students.
Xiaodong Zhang
wiley   +1 more source

High-Frequency Adventitious Shoot Regeneration from Leaf Explants of <i>Jatropha curcas</i> L. [PDF]

Plants (Basel)
Liu B, Chen J, Zhang L, Lu MZ, Liao J, Zhang J.   +5 more
europepmc   +1 more source